Article
Veterinary Sciences
Sarah Humphreys, Philip H. H. Kass, K. Gary Magdesian, Erin Goodrich, Emily Berryhill
Summary: The study aimed to assess the seasonal variation of ACTH in donkeys throughout a year. The results showed that ACTH concentrations in donkeys peaked in the fall and were lowest in the winter and spring. Donkey ACTH concentrations were significantly higher than the reference ranges for horses. Species-specific reference ranges are necessary for accurate interpretation of endocrinopathy screenings in donkeys.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Environmental Sciences
Zorimar Rivera-Nunez, Megan Hansel, Camila Capurro, Danielle Kozlosky, Christina Wang, Cathleen L. Doherty, Brian Buckley, Pamela Ohman-Strickland, Richard K. Miller, Thomas G. O'Connor, Lauren M. Aleksunes, Emily S. Barrett
Summary: This study found that cadmium exposure during pregnancy may lead to lower testosterone levels in pregnant women, while estrogen levels remain unchanged. This effect may be stronger in pregnancies carrying female fetuses. Further research is needed to understand how alterations in gestational testosterone activity may impact pregnancy and child health.
Article
Endocrinology & Metabolism
Ying Meng, Loralei L. Thornburg, Kathleen M. Hoeger, Zorimar Rivera- Nunez, Amber Kautz, Adam T. Evans, Christina Wang, Richard K. Miller, Susan W. Groth, Thomas G. O'Connor, Emily S. Barrett
Summary: This study aimed to assess the relationships between early-pregnancy sex steroid hormones and the subsequent development of hyperglycemia during pregnancy, as well as the associations between sex steroid hormone levels and gestational diabetes diagnosis. The results showed that total testosterone, free testosterone, and estrone in early pregnancy were positively associated with glucose levels and gestational diabetes in mid-late pregnancy. These hormones may serve as early predictors of gestational diabetes along with other risk factors.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, Research & Experimental
Yelda A. Leal, Minkyo Song, Jovanny Zabaleta, Gilberto Medina-Escobedo, Patrick Caron, Aurelio Lopez-Colombo, Chantal Guillemette, M. Constanza Camargo
Summary: The study suggests that higher levels of circulating DHEA may be associated with a lower risk of noncardia gastric cancer, while estradiol and testosterone levels were not significantly linked to gastric cancer. Further longitudinal studies are needed to explore the temporality of this association and the mechanisms of disease pathogenesis.
ARCHIVES OF MEDICAL RESEARCH
(2021)
Article
Obstetrics & Gynecology
Megan C. Hansel, Hannah R. Murphy, Jessica Brunner, Christina Wang, Richard K. Miller, Thomas G. O'Connor, Emily S. Barrett, Zorimar Rivera-Nunez
Summary: The study found that neighborhood stressors were associated with higher levels of maternal testosterone, which may have implications for maternal and child health.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Multidisciplinary Sciences
Jose O. Valdebenito, Naerhulan Halimubieke, Adam Z. Lendvai, Jordi Figuerola, Gotz Eichhorn, Tamas Szekely
Summary: The study found that immune system in birds exhibit both sex differences and seasonal variations, with males showing higher immune responses and abilities during the breeding season. The study also revealed that sex differences in immune status are more pronounced during the breeding period compared to the non-breeding period.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Ingeborg E. van Zeggeren, Anita Boelen, Diederik van de Beek, Annemieke C. Heijboer, Alexander P. J. Vlaar, Matthijs C. Brouwer
Summary: In patients with severe COVID-19, lower levels of total and free testosterone were associated with mortality in men, while lower SHBG levels were associated with mortality in both men and women. Estradiol levels did not show a significant difference between deceased and surviving patients.
Article
Physiology
Juliana Antero, Steven Golovkine, Louis Niffoi, Alice Meignie, Tom Chassard, Quentin Delarochelambert, Martine Duclos, Carole Maitre, Hugo Maciejewski, Allison Diry, Jean-Francois Toussaint
Summary: This study investigated the impact of menstrual cycle and hormonal contraception on training, performance, and wellness in elite rowers. The results showed that rowers with a natural cycle and those on hormonal contraception had higher performance evaluations during specific phases, but experienced more menstrual symptoms during certain phases. It is crucial to consider menstrual cycle and hormonal contraception data in the monitoring of female athletes' wellness and training, as these factors can affect their perception and performance.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Endocrinology & Metabolism
Christian A. Unger, Marion C. Hope, Ahmed K. Aladhami, William E. Cotham, Cassidy E. Socia, Barton C. Rice, Deborah J. Clegg, Kandy T. Velazquez, Holly A. Lavoie, Fiona Hollis, Reilly T. Enos
Summary: Serum sex steroid levels fluctuate throughout the reproductive cycle, and there are differences between sex steroid tissue content and circulating content. This study investigated the dynamic fluctuations in serum and tissue steroid content during the estrous cycle in mice, and found significant differences in absolute amounts of steroid levels between tissues.
Article
Behavioral Sciences
Diana Armbruster, Clemens Kirschbaum, Alexander Strobel
Summary: Gender and endocrine status have significant effects on moral judgments, with men showing stronger utilitarian tendencies and free cycling women showing stronger deontological tendencies. Testosterone levels are correlated with moral judgments, but the specific associations vary depending on gender and oral contraceptive use.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Review
Critical Care Medicine
Meng Qi Zhang, Kimberly F. Macala, Alison Fox-Robichaud, Asher A. Mendelson, Manoj M. Lalu
Summary: The importance of considering sex and gender in biomedical research is increasingly recognized, particularly in the fields of clinical and preclinical sepsis. Clinical studies are limited by observational data and confounding factors, while preclinical studies offer a unique opportunity to study sex differences. Females may exhibit more favorable outcomes in these studies.
Article
Multidisciplinary Sciences
Cathy Wyse, Grace O'Malley, Andrew N. Coogan, Sam McConkey, Daniel J. Smith
Summary: Seasonal and daytime variability in immune parameters were observed in a large population, independent of lifestyle and environmental factors. These findings suggest that season and time of day should be considered in studies of immunoprophylaxis and disease transmission.
Article
Biochemistry & Molecular Biology
Hendrik Stuelb, Malte Bachmann, Sina Gonther, Heiko Muehl
Summary: This study investigates the role of IL-22 in female mice with acetaminophen-induced liver injury, demonstrating that testosterone and dihydrotestosterone can reduce IL-22 production in female splenocytes. The findings suggest a potential explanation for the increased IL-22 in female mice and splenocytes during inflammatory activation, and highlight the immunosuppressive effects of androgens in males.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Cell Biology
Dominika Borzyszkowska, Mirela Niedzielska, Mateusz Kozlowski, Agnieszka Brodowska, Adam Przepiera, Kinga Malczyk-Matysiak, Aneta Cymbaluk-Ploska, Elzbieta Sowinska-Przepiera
Summary: This study evaluated the hormonal profile of acne vulgaris patients before and after treatment. The results showed a correlation between testosterone, androstendione, and cortisol concentrations and acne severity. Acne in adult women may indicate androgen excess syndrome. Contraceptive therapy is an effective treatment for acne.
Review
Urology & Nephrology
Joel Neugarten, Ladan Golestaneh
Summary: Female sex provides renoprotection in chronic progressive kidney disease, but there is sexual dimorphism in the development of ischemic and nephrotoxic acute kidney injury (AKI). Animal studies demonstrate that female sex helps protect the kidneys against injury, but in humans, female sex is considered an independent risk factor for AKI.
SEMINARS IN NEPHROLOGY
(2022)
Article
Neurosciences
Yoanna A. Kurnianingsih, Sam K. Y. Sim, Michael W. L. Chee, O'Dhaniel A. Mullette-Gillman
FRONTIERS IN HUMAN NEUROSCIENCE
(2015)
Article
Neurosciences
Yoanna A. Kurnianingsih, O'Dhaniel A. Mullette-Gillman
FRONTIERS IN NEUROSCIENCE
(2015)
Article
Neurosciences
O'Dhaniel A. Mullette-Gillman, Yoanna A. Kurnianingsih, Jean C. J. Liu
FRONTIERS IN NEUROSCIENCE
(2015)
Article
Neurosciences
Julian Lim, Paul M. Ho, O'Dhaniel A. Mullette-Gillman
FRONTIERS IN NEUROSCIENCE
(2015)
Article
Neurosciences
O'Dhaniel A. Mullette-Gillman, Jacqueline M. Detwiler, Amy Winecoff, Ian Dobbins, Scott A. Huettel
Article
Neurosciences
Yu-Feng Huang, Chun Siong Soon, O'Dhaniel A. Mullette-Gillman, Po-Jang Hsieh
Article
Multidisciplinary Sciences
Fumihiko Taya, Swati Gupta, Ilya Farber, O'Dhaniel A. Mullette-Gillman
Article
Multidisciplinary Sciences
O'Dhaniel A. Mullette-Gillman, Ruth L. F. Leong, Yoanna A. Kurnianingsih
Correction
Multidisciplinary Sciences
O. A. Mullette-Gillman, R. L. F. Leong, Y. A. Kurnianingsih
Article
Multidisciplinary Sciences
Julian Lim, Yoanna A. Kurnianingsih, How Hwee Ong, O'Dhaniel A. Mullette-Gillman
SCIENTIFIC REPORTS
(2017)
Article
Genetics & Heredity
Cara R. Damiano, Joseph Aloi, Kaitlyn Dunlap, Caley J. Burrus, Maya G. Mosner, Rachel V. Kozink, Ralph Edward McLaurin, O'Dhaniel A. Mullette-Gillman, Ronald McKell Carter, Scott A. Huettel, Francis Joseph McClernon, Allison Ashley-Koch, Gabriel S. Dichter
Article
Psychology, Multidisciplinary
How Hwee Ong, O'Dhaniel A. Mullette-Gillman, Kenneth Kwok, Julian Lim
FRONTIERS IN PSYCHOLOGY
(2014)
Article
Psychology, Multidisciplinary
Steven J. Stanton, O'Dhaniel A. Mullette-Gillman, R. Edward McLaurin, Cynthia M. Kuhn, Kevin S. LaBar, Michael L. Platt, Scott A. Huettel
PSYCHOLOGICAL SCIENCE
(2011)
Meeting Abstract
Neurosciences
Lihong Wang, Brandi Newell, O'Dhaniel A. Mullette-Gillman, Kishore M. Gadde, Cynthia M. Kuhn, Gregory McCarthy, Scott A. Huettel
BIOLOGICAL PSYCHIATRY
(2010)
Article
Psychology, Biological
Umit Yilmaz, Kevser Tanbek
Summary: This study investigated the effects of intracerebroventricular administration of Spexin on the hypothalamus-pituitary-thyroid axis and energy expenditure in rats. The results showed that Spexin reduced food consumption and body weight, increased thyroid hormones, and enhanced energy metabolism.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Kuei-Yu Chien, Yun-Ju Chen, Kuo-Jen Hsu, Chiao-Nan Chen
Summary: This study investigated the effects of a high-protein diet and high-intensity interval training on appetite and weight loss in obese middle-aged individuals. The results showed that consuming a high-protein drink and following a high-protein diet after exercise can reduce post-exercise appetite and the frequency of late-night snacking.
PHYSIOLOGY & BEHAVIOR
(2024)
Review
Psychology, Biological
Melissa Alves Braga Oliveira, Ana Carolina Odebrecht Vergne de Abreu, Debora Barroggi Constantino, Andre C. Tonon, Antoni Diez-Noguera, Fernanda Gaspar Amaral, Maria Paz Hidalgo
Summary: Biological processes in living organisms exhibit strong rhythmicity and are regulated by internal timing systems. Understanding the influence of biological rhythms is crucial for experimental design and reporting.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Yanqun Cao, Hao Chen, Yinna Tan, Xu-Dong Yu, Chuli Xiao, Yin Li, James Reilly, Zhiming He, Xinhua Shu
Summary: There is evidence to suggest that chronic stress impacts neurochemical homeostasis and contributes to mental disorders. This study investigates the therapeutic potential of p-coumaric acid (p-CA), a natural compound found in vegetables and fruits, against stress-associated mental disorders. The findings suggest that p-CA could alleviate cognitive deficits and depression-like behavior in mice exposed to chronic restraint stress (CRS) by regulating the PKA-CREB-BDNF signaling pathway.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Mai O. Spaulding, Jessica R. Hoffman, Grace C. Madu, Magen N. Lord, Caroline Soares Iizuka, Kevin P. Myers, Emily E. Noble
Summary: Food insecurity is associated with obesity and disordered eating behaviors. Studying a rodent model, researchers found that adolescent food insecurity may increase susceptibility to obesity and altered eating behaviors during adulthood.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
K. Oberman, B. L. van Leeuwen, M. Nabben, J. E. Villafranca, R. G. Schoemaker
Summary: The present study investigated the post-operative complications and therapeutic potential of J147 in male Zucker rats, and found that J147 treatment had positive effects on behavioral and metabolic parameters, but did not affect neuroinflammation. The results suggest that a combination of acute and chronic J147 treatment may be optimal for treatment.
PHYSIOLOGY & BEHAVIOR
(2024)
Review
Psychology, Biological
Mathieu Cournoyer, Alice Maldera, Alexandre-Charles Gauthier, Fabien Dal Maso, Marie-Eve Mathieu
Summary: This article provides a comprehensive view of the literature on the effect of different odors on physical activity through a systematic review. It was found that pleasant odors have a positive impact on participants' physical activity. However, better methodological consistency is needed in studies to produce more meaningful results.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Gabriel R. Gilmore, Jeff Dyche
Summary: This study examined sleep, sleep/wake regularity, and cognition in college students diagnosed with depression and using serotonergic antidepressants, comparing them to those without a depression diagnosis. The results showed that students using antidepressants had slightly longer wake after sleep onset and lower sleep efficiency, but these differences were likely not noticed by the participants. There were no differences in sleep regularity or cognition between the two groups.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Erica A. Cross, Kim L. Huhman, H. Elliott Albers
Summary: Social stress plays a significant role in the development of neuropsychiatric disorders and can lead to behavioral deficits such as social withdrawal. This study investigates the impact of social stress on social reward in Syrian hamsters. The results show that subordinate and socially defeated males have reduced motivation for social interactions compared to dominant males. Additionally, winning males exhibit greater activation in the mesolimbic dopamine system compared to losers. In females, there were no differences in social entries between winners and losers, but winning females display more activation in the NAc shell.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Daniel A. R. Cabral, Maria L. M. Rego, Eduardo B. Fontes, Vagner D. O. Tavares
Summary: This study examined the association between body mass index (BMI) and negative emotional states (NES) in men with substance use disorders (SUD) undergoing treatment. The findings showed a positive correlation between BMI and stress, anxiety, and depression. These results suggest that reducing body fat accumulation may contribute to improving mental health in individuals with SUD during recovery.
PHYSIOLOGY & BEHAVIOR
(2024)
Review
Psychology, Biological
Elizabeth Agbor Epse Muluh, Jessica C. McCormack, Yunfan Mo, Michael Garratt, Mei Peng
Summary: This PROSPERO pre-registered systematic review and meta-analysis evaluated the olfactory and gustatory changes in pregnant individuals. The meta-analysis revealed that pregnant individuals performed poorer in odour identification, rated olfactory stimuli to be more intense during the second and third trimester, and had increased pleasantness for sweet taste in the first trimester. No major difference was observed in terms of gustatory functions between pregnant and non-pregnant subjects.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Renee Spiteri Douglas, Mackenzie R. Hartley, J. Renee Yang, Tamara B. Franklin
Summary: The expression of Hdac2 in the hippocampus is associated with social status, while the expression of closely related genes Hdac1 and HDAC2 protein is not associated with social rank in the hippocampus.
PHYSIOLOGY & BEHAVIOR
(2024)