Review
Endocrinology & Metabolism
Vinithra Ponnusamy, Gowtham Subramanian, Karthi Muthuswamy, Deepankumar Shanmugamprema, Vasanth Krishnan, Thirunavukkarasu Velusamy, Selvakumar Subramaniam
Summary: The present review examines the importance of taste sensation in making nutritionally important decisions and its relationship with altered taste sensitivity and genetic polymorphisms in obesity.
Review
Chemistry, Multidisciplinary
Michael Schaefer, Eileen Garbow
Summary: This review explores the psychological effects of sweet taste and its connections to social perceptions and behaviors, as well as its potential role in overweight and obesity. Future research should focus on how sweet taste preference influences eating behaviors to gain a comprehensive understanding of the obesity epidemic.
APPLIED SCIENCES-BASEL
(2021)
Article
Nutrition & Dietetics
Monia Cecati, Arianna Vignini, Francesca Borroni, Sofia Pugnaloni, Sonila Alia, Jacopo Sabbatinelli, Giulia Nicolai, Marina Taus, Andrea Santarelli, Mara Fabri, Laura Mazzanti, Monica Emanuelli
Summary: This study confirmed that genetic variations may account for inter-individual taste perception differences. Individuals carrying specific SNPs were less sensitive to sweet taste recognition, and overall taste recognition was influenced by age and BMI.
Review
Medicine, General & Internal
Gabriela Ribeiro, Albino J. Oliveira-Maia
Summary: Studies suggest that individuals with obesity may have decreased taste perception, particularly for sweet tastes, while energy deficit resulting from dieting may increase sensitivity to palatable foods. However, the association between obesity and reduced sweet taste perception remains inconclusive due to conflicting findings in research.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Shih-Yi Lin, Ya-Yu Wang, Pin-Ho Pan, Jiaan-Der Wang, Ching-Ping Yang, Wen-Ying Chen, Yu-Hsiang Kuan, Su-Lan Liao, Yu-Li Lo, Yih-Hsin Chang, Chun-Jung Chen
Summary: This study investigated the effects of DHA on obesity-related inflammation and adipose tissue browning in obese mice. The results showed that DHA improved obesity phenotypes, including insulin resistance, inflammation, and macrophage polarization in the liver and adipose tissues. Furthermore, DHA alleviated dysregulated adipokines and impaired thermogenic and browning molecules, along with ER stress and mitochondrial dysfunction.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2023)
Article
Food Science & Technology
Xiaozhen Zhu, Ting Ren, Qiushuang Xiong, Zhengfeng Lin, Xiaoxiao Lin, Guangyong Lin
Summary: Recent reports suggest that salidroside protects cardiomyocytes from oxidative injury and stimulates glucose uptake by skeletal muscle cells. Despite these findings, the therapeutic potential of salidroside in the treatment of obesity and insulin resistance remains uncertain and requires further investigation.
FOOD SCIENCE & NUTRITION
(2023)
Article
Psychology, Biological
Ezen Choo, Anna Koh, Jason Goodman, Jennifer Bushnell, Hanna Mielke-Maday, Bryan Merte, Robin Dando
Summary: During pregnancy, maternal taste preferences change, likely due to alterations in taste buds' expression profile, which may promote a less healthy diet while expecting.
PHYSIOLOGY & BEHAVIOR
(2021)
Article
Nutrition & Dietetics
Arnaud Bernard, Johanne Le Beyec-Le Bihan, Loredana Radoi, Muriel Coupaye, Ouidad Sami, Nathalie Casanova, Cedric Le May, Xavier Collet, Pascaline Delaby, Cindy Le Bourgot, Philippe Besnard, Severine Ledoux
Summary: This study aimed to explore the impact of bariatric surgery on taste perceptions, finding that only RYGB surgery led to changes in fat sensitivity. However, perceptions of fat and sweet tastes were not consistent among patients who underwent the same surgery.
Article
Biochemistry & Molecular Biology
Sergio Quesada-Vazquez, Anna Antolin, Marina Colom-Pellicer, Gerard Aragones, Laura Herrero, Josep Maria Del Bas, Antoni Caimari, Xavier Escote
Summary: A specific combination of metabolic cofactors showed promising results in treating obesity in a high-fat diet mouse model. The combination reduced obesity and adiposity, improved glucose and lipid metabolic parameters, increased lipid oxidation, and decreased adipocyte hypertrophy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Nutrition & Dietetics
Klara Wilk, Wiktoria Korytek, Marta Pelczynska, Malgorzata Moszak, Pawel Bogdanski
Summary: Excessive consumption of sugar-rich foods is a major factor contributing to the global obesity pandemic, and obesity in turn can lead to reduced sensitivity to sweet taste and changes in appetite. Non-nutritive sweeteners (NNS) offer a potential method for reducing caloric intake while maintaining sweetness, although their effects on appetite regulation and sweet taste perception are not yet fully understood.
Article
Food Science & Technology
Mei Peng, Rachel Ginieis, Sashie Abeywickrema, Jessica McCormack, John Prescott
Summary: This study aims to test individual-based rejection thresholds to sucrose concentrations and evaluate the relationship between these measures and sugar intake behavior. The results demonstrate that rejection thresholds can be estimated at an individual level. Descending rejection thresholds are positively correlated with sweet liking and are significant predictors of overall dietary sugar intakes and sugar intakes from sweetened beverages. These findings suggest that descending rejection thresholds can be used to detect a sensory-diet relationship and inform sugar reduction targets.
FOOD QUALITY AND PREFERENCE
(2023)
Article
Nutrition & Dietetics
Gabriela Ribeiro, Sandra Torres, Ana B. Fernandes, Marta Camacho, Teresa L. Branco, Sandra S. Martins, Armando Raimundo, Albino J. Oliveira-Maia
Summary: The study found that individuals with obesity reported higher sweet taste intensity ratings compared to healthy controls. Additionally, while psychological measures of reward-related feeding behavior assessed a common construct, sweet intensity perception may represent a different dimension related to obesity.
FRONTIERS IN NUTRITION
(2022)
Article
Cell Biology
Juhee Kim, Myoungsook Lee
Summary: Obesity can lead to various complications such as diabetes, hypertension, fatty liver, cardiovascular diseases, and cancer. A pilot study identified the DNAJC6 gene as significantly related to resting metabolic rate (RMR) in childhood obesity. Further investigation revealed that overexpression of DNAJC6 causes a new mechanism in obesity, including suppressed adipogenesis, decreased lipolysis resistance, reduced adipokine expression, disrupted insulin signaling, and impaired mitochondrial functions.
Article
Food Science & Technology
David Guedes, Marilia Prada, Margarida V. Garrido, Ines Caeiro, Carla Simoes, Elsa Lamy
Summary: This study investigated the effects of music on sweet taste perception, specifically on detection, recognition, and intensity ratings of sucrose solutions. The results suggest that the influence of music on sweet taste perception may vary depending on the specific parameter being measured.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Cell Biology
Yunpo Zhao, Emilia Johansson, Jianli Duan, Zhe Han, Mattias Alenius
Summary: This study investigates the interaction between taste perception and macronutrients. It reveals that fat overconsumption reduces fatty acid taste and increases sweet perception, while sugar intake enhances fatty acid perception and suppresses sweet taste. The study further uncovers the signaling pathways involved in regulating taste perception in response to sugar and fat.
Article
Psychology, Biological
Umit Yilmaz, Kevser Tanbek
Summary: This study investigated the effects of intracerebroventricular administration of Spexin on the hypothalamus-pituitary-thyroid axis and energy expenditure in rats. The results showed that Spexin reduced food consumption and body weight, increased thyroid hormones, and enhanced energy metabolism.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Kuei-Yu Chien, Yun-Ju Chen, Kuo-Jen Hsu, Chiao-Nan Chen
Summary: This study investigated the effects of a high-protein diet and high-intensity interval training on appetite and weight loss in obese middle-aged individuals. The results showed that consuming a high-protein drink and following a high-protein diet after exercise can reduce post-exercise appetite and the frequency of late-night snacking.
PHYSIOLOGY & BEHAVIOR
(2024)
Review
Psychology, Biological
Melissa Alves Braga Oliveira, Ana Carolina Odebrecht Vergne de Abreu, Debora Barroggi Constantino, Andre C. Tonon, Antoni Diez-Noguera, Fernanda Gaspar Amaral, Maria Paz Hidalgo
Summary: Biological processes in living organisms exhibit strong rhythmicity and are regulated by internal timing systems. Understanding the influence of biological rhythms is crucial for experimental design and reporting.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Yanqun Cao, Hao Chen, Yinna Tan, Xu-Dong Yu, Chuli Xiao, Yin Li, James Reilly, Zhiming He, Xinhua Shu
Summary: There is evidence to suggest that chronic stress impacts neurochemical homeostasis and contributes to mental disorders. This study investigates the therapeutic potential of p-coumaric acid (p-CA), a natural compound found in vegetables and fruits, against stress-associated mental disorders. The findings suggest that p-CA could alleviate cognitive deficits and depression-like behavior in mice exposed to chronic restraint stress (CRS) by regulating the PKA-CREB-BDNF signaling pathway.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Mai O. Spaulding, Jessica R. Hoffman, Grace C. Madu, Magen N. Lord, Caroline Soares Iizuka, Kevin P. Myers, Emily E. Noble
Summary: Food insecurity is associated with obesity and disordered eating behaviors. Studying a rodent model, researchers found that adolescent food insecurity may increase susceptibility to obesity and altered eating behaviors during adulthood.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
K. Oberman, B. L. van Leeuwen, M. Nabben, J. E. Villafranca, R. G. Schoemaker
Summary: The present study investigated the post-operative complications and therapeutic potential of J147 in male Zucker rats, and found that J147 treatment had positive effects on behavioral and metabolic parameters, but did not affect neuroinflammation. The results suggest that a combination of acute and chronic J147 treatment may be optimal for treatment.
PHYSIOLOGY & BEHAVIOR
(2024)
Review
Psychology, Biological
Mathieu Cournoyer, Alice Maldera, Alexandre-Charles Gauthier, Fabien Dal Maso, Marie-Eve Mathieu
Summary: This article provides a comprehensive view of the literature on the effect of different odors on physical activity through a systematic review. It was found that pleasant odors have a positive impact on participants' physical activity. However, better methodological consistency is needed in studies to produce more meaningful results.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Gabriel R. Gilmore, Jeff Dyche
Summary: This study examined sleep, sleep/wake regularity, and cognition in college students diagnosed with depression and using serotonergic antidepressants, comparing them to those without a depression diagnosis. The results showed that students using antidepressants had slightly longer wake after sleep onset and lower sleep efficiency, but these differences were likely not noticed by the participants. There were no differences in sleep regularity or cognition between the two groups.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Erica A. Cross, Kim L. Huhman, H. Elliott Albers
Summary: Social stress plays a significant role in the development of neuropsychiatric disorders and can lead to behavioral deficits such as social withdrawal. This study investigates the impact of social stress on social reward in Syrian hamsters. The results show that subordinate and socially defeated males have reduced motivation for social interactions compared to dominant males. Additionally, winning males exhibit greater activation in the mesolimbic dopamine system compared to losers. In females, there were no differences in social entries between winners and losers, but winning females display more activation in the NAc shell.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Daniel A. R. Cabral, Maria L. M. Rego, Eduardo B. Fontes, Vagner D. O. Tavares
Summary: This study examined the association between body mass index (BMI) and negative emotional states (NES) in men with substance use disorders (SUD) undergoing treatment. The findings showed a positive correlation between BMI and stress, anxiety, and depression. These results suggest that reducing body fat accumulation may contribute to improving mental health in individuals with SUD during recovery.
PHYSIOLOGY & BEHAVIOR
(2024)
Review
Psychology, Biological
Elizabeth Agbor Epse Muluh, Jessica C. McCormack, Yunfan Mo, Michael Garratt, Mei Peng
Summary: This PROSPERO pre-registered systematic review and meta-analysis evaluated the olfactory and gustatory changes in pregnant individuals. The meta-analysis revealed that pregnant individuals performed poorer in odour identification, rated olfactory stimuli to be more intense during the second and third trimester, and had increased pleasantness for sweet taste in the first trimester. No major difference was observed in terms of gustatory functions between pregnant and non-pregnant subjects.
PHYSIOLOGY & BEHAVIOR
(2024)
Article
Psychology, Biological
Renee Spiteri Douglas, Mackenzie R. Hartley, J. Renee Yang, Tamara B. Franklin
Summary: The expression of Hdac2 in the hippocampus is associated with social status, while the expression of closely related genes Hdac1 and HDAC2 protein is not associated with social rank in the hippocampus.
PHYSIOLOGY & BEHAVIOR
(2024)