King of the Mountains: Tibetan and Sherpa Physiological Adaptations for Life at High Altitude

Admixture facilitates genetic adaptations to high altitude in Tibet

(2014) Choongwon Jeong et al.   Nature Communications

Tibetans living at sea level have a hyporesponsive hypoxia-inducible factor system and blunted physiological responses to hypoxia

(2013) Nayia Petousi et al.   JOURNAL OF APPLIED PHYSIOLOGY

Nitric oxide in adaptation to altitude

(2012) Cynthia M. Beall et al.   FREE RADICAL BIOLOGY AND MEDICINE

’ome on the Range: Altitude Adaptation, Positive Selection, and Himalayan Genomics

(2011) Martin J. MacInnis et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Hypoxia: Adapting to High Altitude by Mutating EPAS-1, the Gene Encoding HIF-2α

(2011) Martha C. Tissot van Patot et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

The Effect of Altitude-Induced Hypoxia on Heart Disease: Do Acute, Intermittent, and Chronic Exposures Provide Cardioprotection?

(2011) John D. Anderson et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Cerebral Artery Dilatation Maintains Cerebral Oxygenation at Extreme Altitude and in Acute Hypoxia—An Ultrasound and MRI Study

(2011) Mark H Wilson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

On the Origin of Tibetans and Their Genetic Basis in Adapting High-Altitude Environments

(2011) Binbin Wang et al.   PLoS One

Humans at high altitude: Hypoxia and fetal growth

(2011) Lorna G. Moore et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

The role of nitrogen oxides in human adaptation to hypoxia

(2011) Denny Z. Levett et al.   Scientific Reports

Elevated pulmonary artery pressure among Amhara highlanders in Ethiopia

(2010) Brian D. Hoit et al.   AMERICAN JOURNAL OF HUMAN BIOLOGY

Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia

(2010) Denny ZH Levett et al.   BMC Medical Research Methodology

Cardiac response to hypobaric hypoxia: persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt. Everest Base Camp

(2010) Cameron J. Holloway et al.   FASEB JOURNAL

Genetic structures of the Tibetans and the Deng people in the Himalayas viewed from autosomal STRs

(2010) Longli Kang et al.   JOURNAL OF HUMAN GENETICS

Differences in the control of breathing between Himalayan and sea-level residents

(2010) M. Slessarev et al.   JOURNAL OF PHYSIOLOGY-LONDON

A Genome-Wide Search for Signals of High-Altitude Adaptation in Tibetans

(2010) S. Xu et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genetic Variations in Tibetan Populations and High-Altitude Adaptation at the Himalayas

(2010) Y. Peng et al.   MOLECULAR BIOLOGY AND EVOLUTION

Natural selection on EPAS1 (HIF2 ) associated with low hemoglobin concentration in Tibetan highlanders

(2010) C. M. Beall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genes for High Altitudes

(2010) J. F. Storz   SCIENCE

Genetic Evidence for High-Altitude Adaptation in Tibet

(2010) T. S. Simonson et al.   SCIENCE

Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude

(2010) X. Yi et al.   SCIENCE

Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data

(2010) Abigail Bigham et al.   PLoS Genetics

Muscle Bioenergetics and Metabolic Control at Altitude

(2009) Paolo Cerretelli et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Mitochondrial genome evidence reveals successful Late Paleolithic settlement on the Tibetan Plateau

(2009) Mian Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic adaptation of skeletal muscle to high altitude hypoxia: how new technologies could resolve the controversies

(2009) Andrew J Murray   Genome Medicine

Angiogenic/lymphangiogenic factors and adaptation to extreme altitudes during an expedition to Mount Everest

(2008) M. Patitucci et al.   Acta Physiologica

Do high-altitude natives have enhanced exercise performance at altitude?

(2008) Tom D. Brutsaert   Applied Physiology Nutrition and Metabolism

Tibetans Retained Innate Ability Resistance to Acute Hypoxia after Long Period of Residing at Sea Level

(2008) Zhao-Nian Zhou et al.   Journal of Physiological Sciences

Why are the high altitude inhabitants like the Tibetans shorter and lighter?

(2008) N.S. Panesar   MEDICAL HYPOTHESES

Adaptation to High Altitude in Sherpas: Association with the Insertion/Deletion Polymorphism in the Angiotensin-Converting Enzyme Gene

(2008) Yunden Droma et al.   WILDERNESS & ENVIRONMENTAL MEDICINE