Endothelial Fatty Acid Transport: Role of Vascular Endothelial Growth Factor B

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

(2012) Carolina E. Hagberg et al.   NATURE

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

FATP4 contributes as an enzyme to the basal and insulin-mediated fatty acid uptake of C2C12 muscle cells

(2011) Margarete Digel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Impaired Insulin Signaling in Endothelial Cells Reduces Insulin-Induced Glucose Uptake by Skeletal Muscle

(2011) Tetsuya Kubota et al.   Cell Metabolism

Brown adipose tissue activity controls triglyceride clearance

(2011) Alexander Bartelt et al.   NATURE MEDICINE

CD36 as a lipid sensor

(2011) Céline Martin et al.   PHYSIOLOGY & BEHAVIOR

Skeletal Muscle-Specific Expression of PGC-1α-b, an Exercise-Responsive Isoform, Increases Exercise Capacity and Peak Oxygen Uptake

(2011) Miki Tadaishi et al.   PLoS One

Complicated life, complicated VEGF-B

(2011) Xuri Li et al.   TRENDS IN MOLECULAR MEDICINE

FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase

(2010) Alaric Falcon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

(2010) Richard C. Scarpulla   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Transcriptional Control of Brown Fat Development

(2010) Shingo Kajimura et al.   Cell Metabolism

GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries

(2010) Brandon S.J. Davies et al.   Cell Metabolism

Vascular Endothelial Growth Factor-B Acts as a Coronary Growth Factor in Transgenic Rats Without Inducing Angiogenesis, Vascular Leak, or Inflammation

(2010) Maija Bry et al.   CIRCULATION

Triglyceride lipases and atherosclerosis

(2010) Gunilla Olivecrona et al.   CURRENT OPINION IN LIPIDOLOGY

Targeting Ceramide Synthesis to Reverse Insulin Resistance

(2010) C. Schmitz-Peiffer   DIABETES

Fatty Acid (FFA) Transport in Cardiomyocytes Revealed by Imaging Unbound FFA Is Mediated by an FFA Pump Modulated by the CD36 Protein

(2010) Andrew N. Carley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vascular endothelial growth factor B controls endothelial fatty acid uptake

(2010) Carolina E. Hagberg et al.   NATURE

Metabolism and Vascular Fatty Acid Transport

(2010) Deborah M. Muoio   NEW ENGLAND JOURNAL OF MEDICINE

Membrane Fatty Acid Transporters as Regulators of Lipid Metabolism: Implications for Metabolic Disease

(2010) Jan F. C. Glatz et al.   PHYSIOLOGICAL REVIEWS

Fatty acid transport across the cell membrane: Regulation by fatty acid transporters

(2010) Robert W. Schwenk et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

VEGF-B

(2010) Xuri Li et al.   Cell Adhesion & Migration

Mutations in the Fatty Acid Transport Protein 4 Gene Cause the Ichthyosis Prematurity Syndrome

(2009) Joakim Klar et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Sarcolemmal fatty acid uptake vs. mitochondrial β-oxidation as target to regress cardiac insulin resistanceThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

(2009) Joost J.F.P. Luiken   Applied Physiology Nutrition and Metabolism

The metabolism of triglyceride-rich lipoproteins revisited: New players, new insight

(2009) Geesje M. Dallinga-Thie et al.   ATHEROSCLEROSIS

The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice

(2009) Jenni Huusko et al.   CARDIOVASCULAR RESEARCH

Vascular Endothelial Growth Factor-B Induces Myocardium-Specific Angiogenesis and Arteriogenesis via Vascular Endothelial Growth Factor Receptor-1– and Neuropilin Receptor-1–Dependent Mechanisms

(2009) Johanna E. Lähteenvuo et al.   CIRCULATION

Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells

(2009) Harun Elmasri et al.   FASEB JOURNAL

Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction

(2009) Lorena Zentilin et al.   FASEB JOURNAL

Additive effects of insulin and muscle contraction on fatty acid transport and fatty acid transporters, FAT/CD36, FABPpm, FATP1, 4 and 6

(2009) Swati S. Jain et al.   FEBS LETTERS

Structure and function of VEGF receptors

(2009) Edward Stuttfeld et al.   IUBMB LIFE

VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

(2009) F. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

(2009) R. L. Silverstein et al.   Science Signaling

Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking

(2008) Angel Sandoval et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Reevaluation of the Role of VEGF-B Suggests a Restricted Role in the Revascularization of the Ischemic Myocardium

(2008) Xuri Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Inflammation, Insulin Resistance, and Reduced Nitric Oxide Production Precede the Onset of Peripheral Insulin Resistance

(2008) Francis Kim et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor

(2008) L. M. Acevedo et al.   BLOOD

Overexpression of Vascular Endothelial Growth Factor-B in Mouse Heart Alters Cardiac Lipid Metabolism and Induces Myocardial Hypertrophy

(2008) Terhi Karpanen et al.   CIRCULATION RESEARCH

Neuropilin-1-VEGFR-2 Complexing Requires the PDZ-binding Domain of Neuropilin-1

(2008) Claudia Prahst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and functional analysis of fatty acid-binding proteins

(2008) Judith Storch et al.   JOURNAL OF LIPID RESEARCH

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome

(2008) M.-Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paradoxical effects of increased expression of PGC-1  on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

(2008) C. S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA