Journal
PHYSIOLOGY
Volume 27, Issue 3, Pages 140-147Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00001.2012
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Funding
- European Research Council [260290] Funding Source: Medline
- Medical Research Council [G1001539] Funding Source: Medline
- European Research Council (ERC) [260290] Funding Source: European Research Council (ERC)
- MRC [G1001539] Funding Source: UKRI
- Medical Research Council [G1001539] Funding Source: researchfish
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Human airways are a paragon of intrinsic engineering. They experience 7,000-10,000 liters of airflow/day, have a 70-m(2) surface area, and undergo complete renewal every 100-400 days. Despite this, airways are susceptible to aging, injury, and diseases that are major causes of mortality. Current airway regeneration research is focused both on understanding the cells and strategies responsible for maintaining intrinsic tissue homeostasis as well as on establishing clinical interventions for improving repair.
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