Journal
PHYSIOLOGY
Volume 26, Issue 2, Pages 106-114Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00039.2010
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Funding
- National Heart, Lung, and Blood Institute [F32 HL-099029, HL-098954]
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Proteasome biology has taken central stage in cardiac physiology and pathophysiology. The molecular heterogeneity of proteasome subpopulations supports the specificity of proteasome function to degrade diverse substrate repertoires. Unveiling the dynamics of proteasome function should inspire new therapeutic strategies for combating cardiac disease.
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