Engineered GPCRs as Tools to Modulate Signal Transduction

Gα-Subunits Differentially Alter the Conformation and Agonist Affinity of κ-Opioid Receptors†

(2008) Feng Yan et al.   BIOCHEMISTRY

Anatomical Profiling of G Protein-Coupled Receptor Expression

(2008) Jean B. Regard et al.   CELL

New Insights into the Function of M4 Muscarinic Acetylcholine Receptors Gained Using a Novel Allosteric Modulator and a DREADD (Designer Receptor Exclusively Activated by a Designer Drug)

(2008) V. Nawaratne et al.   MOLECULAR PHARMACOLOGY

Engineering GPCR signaling pathways with RASSLs

(2008) Bruce R Conklin et al.   NATURE METHODS

Arresting serotonin

(2008) A. Abbas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass

(2008) E. C. Hsiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of a Gi-coupled receptor in the heart causes impaired Ca2+ handling, myofilament injury, and dilated cardiomyopathy

(2007) Diana T. McCloskey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Conditional Expression of a Gi-Coupled Receptor in Osteoblasts Results in Trabecular Osteopenia

(2007) J. Peng et al.   ENDOCRINOLOGY