Interstitial Cells: Regulators of Smooth Muscle Function

Expression and function of a T-type Ca2+ conductance in interstitial cells of Cajal of the murine small intestine

(2014) Haifeng Zheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Telocytes express PDGFRα in the human gastrointestinal tract

(2014) Maria-Giuliana Vannucchi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Interstitial cells of Cajal mediate excitatory sympathetic neurotransmission in guinea pig prostate

(2013) Jiang-ping Wang et al.   CELL AND TISSUE RESEARCH

Cell-Specific Deletion of Nitric Oxide–Sensitive Guanylyl Cyclase Reveals a Dual Pathway for Nitrergic Neuromuscular Transmission in the Murine Fundus

(2013) Dieter Groneberg et al.   GASTROENTEROLOGY

Correlation of cellular expression with function of NO-sensitive guanylyl cyclase in the murine lower urinary tract

(2013) Barbara Lies et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ca2+sensitization pathways accessed by cholinergic neurotransmission in the murine gastric fundus

(2013) Bhupal P. Bhetwal et al.   JOURNAL OF PHYSIOLOGY-LONDON

Distribution and Ca2+signalling of fibroblast-like (PDGFRα+) cells in the murine gastric fundus

(2013) Salah A. Baker et al.   JOURNAL OF PHYSIOLOGY-LONDON

The bioelectrical basis and validity of gastrointestinal extracellular slow wave recordings

(2013) Timothy R. Angeli et al.   JOURNAL OF PHYSIOLOGY-LONDON

Impaired heme oxygenase-1 induction in the gastric antrum induces disruption of the interstitial cells of Cajal network in a rat model of streptozotocin-induced diabetes

(2013) S. Mogami et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Functional Innervation of Guinea-Pig Bladder Interstitial Cells of Cajal Subtypes: Neurogenic Stimulation Evokes In Situ Calcium Transients

(2013) Susannah M. Gray et al.   PLoS One

Kit Signaling Is Required for Development of Coordinated Motility Patterns in Zebrafish Gastrointestinal Tract

(2013) Adam Rich et al.   Zebrafish

Interstitial cells of Cajal integrate excitatory and inhibitory neurotransmission with intestinal slow-wave activity

(2013) Sabine Klein et al.   Nature Communications

Interstitial cells in the primate gastrointestinal tract

(2012) Peter J. Blair et al.   CELL AND TISSUE RESEARCH

Ultra-structural identification of interstitial cells of Cajal in the zebrafish Danio rerio

(2012) Evan R. Ball et al.   CELL AND TISSUE RESEARCH

Differentiation of Interstitial Cells of Cajal in the Human Distal Colon

(2012) Goran Radenkovic et al.   CELLS TISSUES ORGANS

Platelet-derived growth factor receptor α-positive cells in thetunica muscularisof human colon

(2012) Masaaki Kurahashi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Functional expression of SK channels in murine detrusor PDGFRα+cells

(2012) Haeyeong Lee et al.   JOURNAL OF PHYSIOLOGY-LONDON

P2Y1 purinoreceptors are fundamental to inhibitory motor control of murine colonic excitability and transit

(2012) Sung Jin Hwang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Identification of PDGFRα Positive Populations of Interstitial Cells in Human and Guinea Pig Bladders

(2012) Kevin P. Monaghan et al.   JOURNAL OF UROLOGY

Regulation of gastrointestinal motility—insights from smooth muscle biology

(2012) Kenton M. Sanders et al.   Nature Reviews Gastroenterology & Hepatology

The enteric nervous system and neurogastroenterology

(2012) John B. Furness   Nature Reviews Gastroenterology & Hepatology

Ionic conductances regulating the excitability of colonic smooth muscles

(2012) S. D. Koh et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Relationship between enteric neurons and interstitial cells in the primate gastrointestinal tract

(2012) P. J. Blair et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Clinical-histological associations in gastroparesis: results from the Gastroparesis Clinical Research Consortium

(2012) M. Grover et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Stem Cell Factor Receptor/c-Kit: From Basic Science to Clinical Implications

(2012) Johan Lennartsson et al.   PHYSIOLOGICAL REVIEWS

Ultrastructural identification of interstitial cells of Cajal in hen oviduct

(2012) J. A. Gandahi et al.   POULTRY SCIENCE

Identification of a Hyperpolarization-activated Cyclic Nucleotide-gated Channel and Its Subtypes in the Urinary Bladder of the Rat

(2012) Peng He et al.   UROLOGY

Identification of T-type Calcium Channels in the Interstitial Cells of Cajal in Rat Bladder

(2012) Jianping Deng et al.   UROLOGY

Complex effects of imatinib on spontaneous and oxytocin-induced contractions in human non-pregnant myometrium

(2011) S. Cretoiu et al.   ACTA PHYSIOLOGICA HUNGARICA

Gastrointestinal neuromuscular pathology in chronic constipation

(2011) Charles H. Knowles et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Potassium and ANO1/ TMEM16A chloride channel profiles distinguish atypical and typical smooth muscle cells from interstitial cells in the mouse renal pelvis

(2011) Javed Iqbal et al.   BRITISH JOURNAL OF PHARMACOLOGY

Relationship between interstitial cells of Cajal, fibroblast-like cells and inhibitory motor nerves in the internal anal sphincter

(2011) Caroline A. Cobine et al.   CELL AND TISSUE RESEARCH

Different distribution of c-kit positive interstitial cells of Cajal-like in children’s urinary bladders

(2011) Anna Małgorzata Piaseczna-Piotrowska et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Cellular Changes in Diabetic and Idiopathic Gastroparesis

(2011) Madhusudan Grover et al.   GASTROENTEROLOGY

Diagnosis of Gastrointestinal Stromal Tumor (GIST) on Transurethral Resection of the Prostate

(2011) Eleftherios Anagnostou et al.   INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

Altered Expression of Ano1 Variants in Human Diabetic Gastroparesis

(2011) Amelia Mazzone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two patterns of development of interstitial cells of Cajal in the human duodenum

(2011) Goran Radenkovic   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Altered distribution of interstitial cells and innervation in the rat urinary bladder following spinal cord injury

(2011) Louise Johnston et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Platelet-derived growth factor receptor-α cells in mouse urinary bladder: a new class of interstitial cells

(2011) Byoung H. Koh et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Analysis of pacemaker activity in the human stomach

(2011) Poong-Lyul Rhee et al.   JOURNAL OF PHYSIOLOGY-LONDON

Muscarinic activation of Ca2+-activated Cl−current in interstitial cells of Cajal

(2011) Mei Hong Zhu et al.   JOURNAL OF PHYSIOLOGY-LONDON

M3 Muscarinic Receptor-Like Immunoreactivity in Sham Operated and Obstructed Guinea Pig Bladders

(2011) Simone Grol et al.   JOURNAL OF UROLOGY

Spontaneous Ca2+ Signaling of Interstitial Cells in the Guinea Pig Prostate

(2011) Michelle Lam et al.   JOURNAL OF UROLOGY

Ultrastructural Properties of Interstitial Cells of Cajal in the Guinea Pig Bladder

(2011) Rebecca M.J. Cunningham et al.   JOURNAL OF UROLOGY

Gastroparesis: pathogenesis, diagnosis and management

(2011) William L. Hasler   Nature Reviews Gastroenterology & Hepatology

Movement based artifacts may contaminate extracellular electrical recordings from GI muscles

(2011) O. Bayguinov et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Vagal intramuscular array afferents form complexes with interstitial cells of Cajal in gastrointestinal smooth muscle: analogues of muscle spindle organs?

(2011) T.L. Powley et al.   NEUROSCIENCE

Distribution of interstitial cells of cajal and expression of nitric oxide synthase after experimental bladder outlet obstruction in a rat model of bladder overactivity

(2011) Sun-Ouck Kim et al.   NEUROUROLOGY AND URODYNAMICS

Roles of Stem Cell Factor on Loss of Interstitial Cells of Cajal in Bladder of Diabetic Rats

(2011) Wei Chen et al.   UROLOGY

Origin and propagation of human gastric slow-wave activity defined by high-resolution mapping

(2010) Gregory O'Grady et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Carbon monoxide reverses diabetic gastroparesis in NOD mice

(2010) Purna C. Kashyap et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Interstitial cells of Cajal in the cynomolgus monkey rectoanal region and their relationship to sympathetic and nitrergic nerves

(2010) C. A. Cobine et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A Model of Slow Wave Propagation and Entrainment Along the Stomach

(2010) Martin L. Buist et al.   ANNALS OF BIOMEDICAL ENGINEERING

The role of c-kit-positive interstitial cells in mediating phasic contractions of bladder strips from streptozotocin-induced diabetic rats

(2010) Bahareh Vahabi et al.   BJU INTERNATIONAL

C-kit-immunopositive interstitial cells of Cajal in human embryonal and fetal oesophagus

(2010) Goran Radenkovic et al.   CELL AND TISSUE RESEARCH

Kitlow Stem Cells Cause Resistance to Kit/Platelet-Derived Growth Factor α Inhibitors in Murine Gastrointestinal Stromal Tumors

(2010) Michael R. Bardsley et al.   GASTROENTEROLOGY

Functions of ICC-like cells in the urinary tract and male genital organs

(2010) Hikaru Hashitani et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TELOCYTES - a case of serendipity: the winding way from Interstitial Cells of Cajal (ICC), via Interstitial Cajal-Like Cells (ICLC) to TELOCYTES

(2010) L. M. Popescu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Neuroeffector apparatus in gastrointestinal smooth muscle organs

(2010) Kenton M. Sanders et al.   JOURNAL OF PHYSIOLOGY-LONDON

A functional role for the ‘fibroblast-like cells’ in gastrointestinal smooth muscles

(2010) Masaaki Kurahashi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effects of Mechanical Stretch on Interstitial Cells of Cajal in Guinea Pig Bladder

(2010) Yongquan Wang et al.   JOURNAL OF SURGICAL RESEARCH

Prostaglandin Receptor EP1 and EP2 Site in Guinea Pig Bladder Urothelium and Lamina Propria

(2010) Mohammad Sajjad Rahnama'i et al.   JOURNAL OF UROLOGY

Morphological Expression of KIT Positive Interstitial Cells of Cajal in Human Bladder

(2010) Louise Johnston et al.   JOURNAL OF UROLOGY

Contractility and Pacemaker Cells in the Prostate Gland

(2010) Dan-Thanh T. Nguyen et al.   JOURNAL OF UROLOGY

Electric Field Model: An Alternative Mechanism for Cell-to-Cell Propagation in Cardiac Muscle and Smooth Muscle

(2010) Nicholas Sperelakis   NEUROGASTROENTEROLOGY AND MOTILITY

Non-peristaltic patterns of motor activity in the guinea-pig proximal colon

(2010) G. W. Hennig et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Distribution and possible role of PDGF-AA and PDGFR-α in the gastrointestinal tract of adult guinea pigs

(2010) Fangxiao Chan et al.   VIRCHOWS ARCHIV

Interstitial cells of Cajal generate spontaneous transient depolarizations in the rat gastric fundus

(2009) Yoshihiko Kito et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Prostaglandin regulation of gastric slow waves and peristalsis

(2009) Abigail S. Forrest et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract

(2009) Pedro J. Gomez-Pinilla et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Neurotransmission in lower esophageal sphincter of W/Wv mutant mice

(2009) Y. Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mounting evidence against the role of ICC in neurotransmission to smooth muscle in the gut

(2009) Raj K. Goyal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A Novel Monoclonal Antibody Against DOG1 is a Sensitive and Specific Marker for Gastrointestinal Stromal Tumors

(2009) Inigo Espinosa et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Plasticity of Interstitial Cells of Cajal: A Study in the Small Intestine of Adult Guinea Pigs

(2009) Feng Mei et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

High-resolution Mapping of In Vivo Gastrointestinal Slow Wave Activity Using Flexible Printed Circuit Board Electrodes: Methodology and Validation

(2009) Peng Du et al.   ANNALS OF BIOMEDICAL ENGINEERING

Immunohistochemical demonstration of c-Kit-negative fibroblast-like cells in murine gastrointestinal musculature

(2009) Satoshi Iino et al.   ARCHIVES OF HISTOLOGY AND CYTOLOGY

Biophysically Based Mathematical Modeling of Interstitial Cells of Cajal Slow Wave Activity Generated from a Discrete Unitary Potential Basis

(2009) R.A. Faville et al.   BIOPHYSICAL JOURNAL

M3muscarinic receptor expression on suburothelial interstitial cells

(2009) Simone Grol et al.   BJU INTERNATIONAL

Comparison of mechanical and electrical activity and interstitial cells of Cajal in urinary bladders from wild-type andW/Wvmice

(2009) KD McCloskey et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ultrastructure of Cajal-like interstitial cells in the human detrusor

(2009) Helle Rasmussen et al.   CELL AND TISSUE RESEARCH

Ultrastructure of interstitial cells of Cajal in myenteric plexus of human colon

(2009) Jüri Johannes Rumessen et al.   CELL AND TISSUE RESEARCH

Distribution and morphological characteristics of the interstitial cells of Cajal in the ileocaecal junction of the guinea-pig

(2009) Sachiko Miyamoto-Kikuta et al.   CELL AND TISSUE RESEARCH

Spontaneous electrical and Ca2+signals in the mouse renal pelvis that drive pyeloureteric peristalsis

(2009) Richard J Lang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Generation and propagation of gastric slow waves

(2009) Dirk F van Helden et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Heterogeneities in ICC Ca2+ Activity Within Canine Large Intestine

(2009) Hyun–Tai Lee et al.   GASTROENTEROLOGY

Physiology, Injury, and Recovery of Interstitial Cells of Cajal: Basic and Clinical Science

(2009) Jan D. Huizinga et al.   GASTROENTEROLOGY

A Model to Study the Phenotypic Changes of Interstitial Cells of Cajal in Gastrointestinal Diseases

(2009) Seungil Ro et al.   GASTROENTEROLOGY

c-Kit-negative fibroblast-like cells express platelet-derived growth factor receptor α in the murine gastrointestinal musculature

(2009) Satoshi Iino et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Myometrial interstitial cells and the coordination of myometrial contractility

(2009) G. Hutchings et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Potential for control of detrusor smooth muscle spontaneous rhythmic contraction by cyclooxygenase products released by interstitial cells of Cajal

(2009) Clinton Collins et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A Ca2+-activated Cl−conductance in interstitial cells of Cajal linked to slow wave currents and pacemaker activity

(2009) Mei Hong Zhu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles

(2009) Sung Jin Hwang et al.   JOURNAL OF PHYSIOLOGY-LONDON

KCNQ Currents and Their Contribution to Resting Membrane Potential and the Excitability of Interstitial Cells of Cajal From the Guinea Pig Bladder

(2009) Ursula A. Anderson et al.   JOURNAL OF UROLOGY

Loss of intramuscular and submuscular interstitial cells of Cajal and associated enteric nerves is related to decreased gastric emptying in streptozotocin-induced diabetes

(2009) x-y. wang et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Interstitial cells of Cajal contain signalling molecules for transduction of nitrergic stimulation in guinea pig caecum

(2009) s. iino et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Studies on expression and function of the TMEM16A calcium-activated chloride channel

(2009) Fen Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uterine Contractions Depend on KIT-Positive Interstitial Cells in the Mouse: Genetic and Pharmacological Evidence

(2008) Sébastien Allix et al.   BIOLOGY OF REPRODUCTION

Chlamydia Infection Causes Loss of Pacemaker Cells and Inhibits Oocyte Transport in the Mouse Oviduct1

(2008) Rose Ellen Dixon et al.   BIOLOGY OF REPRODUCTION

A Biophysically Based Mathematical Model of Unitary Potential Activity in Interstitial Cells of Cajal

(2008) R.A. Faville et al.   BIOPHYSICAL JOURNAL

Effects of imatinib mesylate on spontaneous electrical and mechanical activity in smooth muscle of the guinea-pig stomach

(2008) H Hashitani et al.   BRITISH JOURNAL OF PHARMACOLOGY

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

The transmembrane protein TMEM16A is required for normal development of the murine trachea

(2008) Jason R. Rock et al.   DEVELOPMENTAL BIOLOGY

Heme Oxygenase-1 Protects Interstitial Cells of Cajal From Oxidative Stress and Reverses Diabetic Gastroparesis

(2008) Kyoung Moo Choi et al.   GASTROENTEROLOGY

Progenitors of Interstitial Cells of Cajal in the Postnatal Murine Stomach

(2008) Andrea Lorincz et al.   GASTROENTEROLOGY

Pyloric Sphincter Dysfunction in nNOS−/− and W/Wv Mutant Mice: Animal Models of Gastroparesis and Duodenogastric Reflux

(2008) Digavalli V. Sivarao et al.   GASTROENTEROLOGY

Changes in the Structure and Function of ICC Networks in ICC Hyperplasia and Gastrointestinal Stromal Tumors

(2008) Joong Goo Kwon et al.   GASTROENTEROLOGY

An age-dependent proliferation is involved in the postnatal development of interstitial cells of Cajal in the small intestine of mice

(2008) Feng Mei et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The localization of cyclo-oxygenase immuno-reactivity (COX I-IR) to the urothelium and to interstitial cells in the bladder wall

(2008) R. de Jongh et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Histochemical and ultrastructural characteristics of an interstitial cell type different from ICC and resident in the muscle coat of human gut

(2008) Laura Pieri et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The α1HCa2+channel subunit is expressed in mouse jejunal interstitial cells of Cajal and myocytes

(2008) Simon J. Gibbons et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Disturbed gastrointestinal motility and decreased interstitial cells of Cajal in diabetic db/db mice

(2008) Takahiro Yamamoto et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

TMEM16A confers receptor-activated calcium-dependent chloride conductance

(2008) Young Duk Yang et al.   NATURE

Interstitial cells of Cajal are innervated by nitrergic nerves and express nitric oxide–sensitive guanylate cyclase in the guinea-pig gastrointestinal tract

(2008) S. Iino et al.   NEUROSCIENCE

Immunohistochemistry using an antibody to unphosphorylated connexin 43 to identify human myometrial interstitial cells

(2008) Graham Hutchings et al.   Reproductive Biology and Endocrinology

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE

Chronic intestinal pseudo-obstruction

(2008) Alexandra Antonucci et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Deficiency of intramuscular ICC increases fundic muscle excitability but does not impede nitrergic innervation

(2007) Jan D. Huizinga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Survival dependency of intramuscular ICC on vagal afferent nerves in the cat esophagus

(2007) Jan. D. Huizinga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Altered distribution of interstitial cells in the guinea pig bladder following bladder outlet obstruction

(2007) Yasue Kubota et al.   NEUROUROLOGY AND URODYNAMICS