Fast Synaptic Inhibition in Spinal Sensory Processing and Pain Control

Presynaptic  2-GABAA Receptors in Primary Afferent Depolarization and Spinal Pain Control

(2011) R. Witschi et al.   JOURNAL OF NEUROSCIENCE

Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia

(2011) Wei Xiong et al.   Nature Chemical Biology

Effects of Intrathecal Ketorolac on Human Experimental Pain

(2010) James C. Eisenach et al.   ANESTHESIOLOGY

Enhancement of GABAergic Tonic Currents by Midazolam and Noradrenaline in Rat Substantia Gelatinosa Neurons In Vitro

(2010) Aiko Maeda et al.   ANESTHESIOLOGY

Neurotransmitter transporters expressed in glial cells as regulators of synapse function

(2010) Volker Eulenburg et al.   BRAIN RESEARCH REVIEWS

 -Aminobutyric Acid (GABA) Is an Autocrine Excitatory Transmitter in Human Pancreatic  -Cells

(2010) M. Braun et al.   DIABETES

Glial glycine transporter 1 function is essential for early postnatal survival but dispensable in adult mice

(2010) Volker Eulenburg et al.   GLIA

Ultrastructural analysis of the synaptic connectivity of TRPV1-expressing primary afferent terminals in the rat trigeminal caudal nucleus

(2010) Eun Jin Yeo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Inhibitory neurones of the spinal substantia gelatinosa mediate interaction of signals from primary afferents

(2010) Jihong Zheng et al.   JOURNAL OF PHYSIOLOGY-LONDON

Loss of Inhibitory Interneurons in the Dorsal Spinal Cord and Elevated Itch in Bhlhb5 Mutant Mice

(2010) Sarah E. Ross et al.   NEURON

Targeting astrocyte signaling for chronic pain

(2010) Yong-Jing Gao et al.   Neurotherapeutics

Differential distribution of activated spinal neurons containing glycine and/or GABA and expressing c-fos in acute and chronic pain models

(2010) Mehdi Hossaini et al.   PAIN

Populations of inhibitory and excitatory interneurons in lamina II of the adult rat spinal dorsal horn revealed by a combined electrophysiological and anatomical approach

(2010) Toshiharu Yasaka et al.   PAIN

Glycine and glycine receptor signaling in hippocampal neurons: Diversity, function and regulation

(2010) Tian-Le Xu et al.   PROGRESS IN NEUROBIOLOGY

Lack of Analgesia by Oral Standardized Cannabis Extract on Acute Inflammatory Pain and Hyperalgesia in Volunteers

(2009) Birgit Kraft et al.   ANESTHESIOLOGY

Chloride regulation in the pain pathway

(2009) Theodore J. Price et al.   BRAIN RESEARCH REVIEWS

Stringent Specificity in the Construction of a GABAergic Presynaptic Inhibitory Circuit

(2009) J. Nicholas Betley et al.   CELL

Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain

(2009) Grégory Scherrer et al.   CELL

Plasticity of synaptic inhibition in mouse spinal cord lamina II neurons during early postnatal development and after inactivation of the glycine receptor α3 subunit gene

(2009) M. Rajalu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Differential localization of γ-aminobutyric acid type a and glycine receptor subunits and gephyrin in the human pons, medulla oblongata and uppermost cervical segment of the spinal cord: An immunohistochemical study

(2009) H.J. Waldvogel et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Substance P Drives Endocannabinoid-Mediated Disinhibition in a Midbrain Descending Analgesic Pathway

(2009) G. M. Drew et al.   JOURNAL OF NEUROSCIENCE

Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

(2009) Rebecca P. Seal et al.   NATURE

Coding of pleasant touch by unmyelinated afferents in humans

(2009) Line S Löken et al.   NATURE NEUROSCIENCE

Cation-Chloride Cotransporters and Neuronal Function

(2009) Peter Blaesse et al.   NEURON

Expression of GABAA receptor α3-, θ-, and ε-subunit mRNAs during rat CNS development and immunolocalization of the ε subunit in developing postnatal spinal cord

(2009) J.-R. Pape et al.   NEUROSCIENCE

Soma size distinguishes projection neurons from neurokinin 1 receptor-expressing interneurons in lamina I of the rat lumbar spinal dorsal horn

(2009) K.S. Al Ghamdi et al.   NEUROSCIENCE

Developmental up-regulation of the potassium–chloride cotransporter type 2 in the rat lumbar spinal cord

(2009) A. Stil et al.   NEUROSCIENCE

Direct excitation of spinal GABAergic interneurons by noradrenaline

(2009) Matthias Gassner et al.   PAIN

Brief, low frequency stimulation of rat peripheral C-fibres evokes prolonged microglial-induced central sensitization in adults but not in neonates

(2009) Gareth J. Hathway et al.   PAIN

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

(2009) D. J. Cavanaugh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spinal Endocannabinoids and CB1 Receptors Mediate C-Fiber-Induced Heterosynaptic Pain Sensitization

(2009) A. J. Pernia-Andrade et al.   SCIENCE

Cellular Basis of Itch Sensation

(2009) Y.-G. Sun et al.   SCIENCE

GABAergic analgesia: new insights from mutant mice and subtype-selective agonists

(2009) Hanns Ulrich Zeilhofer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Developing analgesics by enhancing spinal inhibition after injury: GABAA receptor subtypes as novel targets

(2009) Gordon Munro et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A selective role for α3 subunit glycine receptors in inflammatory pain

(2009) Victoria L. Harvey   Frontiers in Molecular Neuroscience

Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine

(2008) Zhe Yang et al.   BIOCHEMICAL PHARMACOLOGY

Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

(2008) Joseph P. Doyle et al.   CELL

A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types

(2008) Myriam Heiman et al.   CELL

A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord

(2008) Dominique Bröhl et al.   DEVELOPMENTAL BIOLOGY

Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons

(2008) Menggui Huang et al.   DEVELOPMENTAL BIOLOGY

The Gastrointestinal Hormone Ghrelin Modulates Inhibitory Neurotransmission in Deep Laminae of Mouse Spinal Cord Dorsal Horn

(2008) Angela M. Vergnano et al.   ENDOCRINOLOGY

A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling

(2008) K. Hori et al.   GENES & DEVELOPMENT

A quantitative study of spinothalamic neurons in laminae I, III, and IV in lumbar and cervical segments of the rat spinal cord

(2008) Khulood M. Al-Khater et al.   JOURNAL OF COMPARATIVE NEUROLOGY

GAT-1 regulates both tonic and phasic GABAAreceptor-mediated inhibition in the cerebral cortex

(2008) Luca Bragina et al.   JOURNAL OF NEUROCHEMISTRY

Developmental Changes in the Fidelity and Short-Term Plasticity of GABAergic Synapses in the Neonatal Rat Dorsal Horn

(2008) Rachel A. Ingram et al.   JOURNAL OF NEUROPHYSIOLOGY

Na+,K+,2Cl− Cotransport and Intracellular Chloride Regulation in Rat Primary Sensory Neurons: Thermodynamic and Kinetic Aspects

(2008) Héctor I. Rocha-González et al.   JOURNAL OF NEUROPHYSIOLOGY

Regional Differences in the Decay Kinetics of GABAA Receptor-Mediated Miniature IPSCs in the Dorsal Horn of the Rat Spinal Cord Are Determined by Mitochondrial Transport of Cholesterol

(2008) P. Inquimbert et al.   JOURNAL OF NEUROSCIENCE

Large Projection Neurons in Lamina I of the Rat Spinal Cord That Lack the Neurokinin 1 Receptor Are Densely Innervated by VGLUT2-Containing Axons and Possess GluR4-Containing AMPA Receptors

(2008) E. Polgar et al.   JOURNAL OF NEUROSCIENCE

Inflammation-Induced Shift in the Valence of Spinal GABA-A Receptor–Mediated Modulation of Nociception in the Adult Rat

(2008) Vanessa C.Z. Anseloni et al.   JOURNAL OF PAIN

Comparison of the Novel Subtype-Selective GABAA Receptor-Positive Allosteric Modulator NS11394 [3'-[5-(1-Hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with Diazepam, Zolpidem, Bretazenil, and Gaboxadol in Rat Models of Inflammatory and Neuropathic Pain

(2008) G. Munro et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Nocistatin and nociceptin exert opposite effects on the excitability of central amygdala nucleus-periaqueductal gray projection neurons

(2008) Ying-Ling Chen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Reversal of pathological pain through specific spinal GABAA receptor subtypes

(2008) Julia Knabl et al.   NATURE

Glycinergic Transmission Shaped by the Corelease of GABA in a Mammalian Auditory Synapse

(2008) Tao Lu et al.   NEURON

GABAA receptors: Subtypes provide diversity of function and pharmacology

(2008) Richard W. Olsen et al.   NEUROPHARMACOLOGY

Responses to 5-HT in morphologically identified neurons in the rat substantia gelatinosa in vitro

(2008) K. Abe et al.   NEUROSCIENCE

Spread of excitation across modality borders in spinal dorsal horn of neuropathic rats

(2008) Doris Schoffnegger et al.   PAIN

Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms

(2008) Alexandre Charlet et al.   PAIN

Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice

(2008) Julia Knabl et al.   PAIN

International Union of Pharmacology. LXX. Subtypes of  -Aminobutyric AcidA Receptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update

(2008) R. W. Olsen et al.   PHARMACOLOGICAL REVIEWS

The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

(2008) B. Abrahamsen et al.   SCIENCE

Postnatal tuning of cutaneous inhibitory receptive fields in the rat

(2007) Lindsay R. Bremner et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neurosteroid modulation of GABAA receptors: Molecular determinants and significance in health and disease

(2007) Elizabeth A. Mitchell et al.   NEUROCHEMISTRY INTERNATIONAL