Thymidine kinase and mtDNA depletion in human cardiomyopathy: epigenetic and translational evidence for energy starvation

Detection of differentially methylated gene promoters in failing and nonfailing human left ventricle myocardium using computation analysis

(2013) Christopher A. Koczor et al.   PHYSIOLOGICAL GENOMICS

The Kinetic Effects on Thymidine Kinase 2 by Enzyme-Bound dTTP May Explain the Mitochondrial Side Effects of Antiviral Thymidine Analogs

(2011) Liya Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart

(2011) Hélène Lemieux et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Thymidine Kinase 2 Deficiency-Induced Mitochondrial DNA Depletion Causes Abnormal Development of Adipose Tissues and Adipokine Levels in Mice

(2011) Joan Villarroya et al.   PLoS One

Bioenergetics of the failing heart

(2010) Renée Ventura-Clapier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Defective DNA Replication Impairs Mitochondrial Biogenesis In Human Failing Hearts

(2010) Georgios Karamanlidis et al.   CIRCULATION RESEARCH

Onset and organ specificity of Tk2 deficiency depends on Tk1 down-regulation and transcriptional compensation

(2010) B. Dorado et al.   HUMAN MOLECULAR GENETICS

Tissue Specific Distribution of Pyrimidine Deoxynucleoside Salvage Enzymes Shed Light on the Mechanism of Mitochondrial DNA Depletion

(2010) L. Wang et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

New aspects of impaired mitochondrial function in heart failure

(2009) Mariana G. Rosca et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy

(2009) James J Kohler et al.   LABORATORY INVESTIGATION

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Cardiac-Targeted Transgenic Mutant Mitochondrial Enzymes: mtDNA Defects, Antiretroviral Toxicity and Cardiomyopathy

(2008) James J. Kohler et al.   Cardiovascular Toxicology

Mitochondrial DNA Impairment in Nucleoside Reverse Transcriptase Inhibitor-Associated Cardiomyopathy

(2008) James J. Kohler et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Mitochondrial centrality in heart failure

(2008) José Marín-García et al.   HEART FAILURE REVIEWS

Murine cardiac mtDNA: effects of transgenic manipulation of nucleoside phosphorylation

(2008) James J Kohler et al.   LABORATORY INVESTIGATION

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats

(2008) Mia Jüllig et al.   PROTEOMICS