Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation

Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53

(2016) Katherine Heminger et al.   Aging-US

FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly

(2011) A. Jurak Begonja et al.   BLOOD

Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome

(2011) K. A. McGowan et al.   BLOOD

Polo-like Kinase Plk2 Is an Epigenetic Determinant of Chemosensitivity and Clinical Outcomes in Ovarian Cancer

(2011) N. Syed et al.   CANCER RESEARCH

Drosophila melanogasterCyclin G coordinates cell growth and cell proliferation

(2011) Floria Faradji et al.   CELL CYCLE

Role of tumor suppressor p53 in megakaryopoiesis and platelet function

(2011) Pani A. Apostolidis et al.   EXPERIMENTAL HEMATOLOGY

Calcium- and Integrin-Binding Protein 1 Regulates Endomitosis and Its Interaction with Polo-Like Kinase 3 Is Enhanced in Endomitotic Dami Cells

(2011) John C. Kostyak et al.   PLoS One

Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes

(2011) J.-W. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process

(2010) L. Lordier et al.   BLOOD

Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery

(2010) X Shawn Liu et al.   EMBO REPORTS

The APC/C recruits cyclin B1–Cdk1–Cks in prometaphase before D box recognition to control mitotic exit

(2010) Wouter van Zon et al.   JOURNAL OF CELL BIOLOGY

The α-granule proteome: novel proteins in normal and ghost granules in gray platelet syndrome

(2010) D. M. MAYNARD et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The clock gene Per2 is required for normal platelet formation and function

(2010) Yue Zhao et al.   THROMBOSIS RESEARCH

Transcriptional Regulation by P53

(2010) R. Beckerman et al.   Cold Spring Harbor Perspectives in Biology

PH Domain-Only Protein PHLDA3 Is a p53-Regulated Repressor of Akt

(2009) Tatsuya Kawase et al.   CELL

Regulation of megakaryocytic differentiation of K562 cells by FosB, a member of the Fos family of AP-1 transcription factors

(2009) J.-K. Limb et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition

(2009) Lisa M. Giammona et al.   EXPERIMENTAL HEMATOLOGY

Human platelet pathology related to defects in the G-protein signaling cascade

(2009) C. VAN GEET et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Polo-like kinases: conservation and divergence in their functions and regulation

(2009) Vincent Archambault et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies

(2008) Michael C Ryan et al.   BMC BIOINFORMATICS

Tumor Suppressor Protein p53 Regulates Megakaryocytic Polyploidization and Apoptosis

(2008) Peter G. Fuhrken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Michigan molecular interactions r2: from interacting proteins to pathways

(2008) V. G. Tarcea et al.   NUCLEIC ACIDS RESEARCH

Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis

(2008) Peter G. Fuhrken et al.   PHYSIOLOGICAL GENOMICS