Separases: biochemistry and function

Metacaspases

(2011) L Tsiatsiani et al.   CELL DEATH AND DIFFERENTIATION

The Radially Swollen 4 Separase Mutation of Arabidopsis thaliana Blocks Chromosome Disjunction and Disrupts the Radial Microtubule System in Meiocytes

(2011) Xiaohui Yang et al.   PLoS One

A Role for Separase in the Regulation of RAB-11-Positive Vesicles at the Cleavage Furrow and Midbody

(2010) Joshua N. Bembenek et al.   CURRENT BIOLOGY

A conditional mutation in Arabidopsis thaliana separase induces chromosome non-disjunction, aberrant morphogenesis and cyclin B1;1 stability

(2010) S. Wu et al.   DEVELOPMENT

Separase Is Recruited to Mitotic Chromosomes to Dissolve Sister Chromatid Cohesion in a DNA-Dependent Manner

(2009) Yuxiao Sun et al.   CELL

Overexpression and Mislocalization of the Chromosomal Segregation Protein Separase in Multiple Human Cancers

(2009) R. Meyer et al.   CLINICAL CANCER RESEARCH

Functional characterization of cohesin SMC3 and separase and their roles in the segregation of large and minichromosomes inTrypanosoma brucei

(2009) Mohamed Bessat et al.   MOLECULAR MICROBIOLOGY

Arabidopsis Separase Functions beyond the Removal of Sister Chromatid Cohesion during Meiosis

(2009) X. Yang et al.   PLANT PHYSIOLOGY

Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms

(2008) Vania Parelho et al.   CELL

Cohesin Complex Promotes Transcriptional Termination between Convergent Genes in S. pombe

(2008) Monika Gullerova et al.   CELL

Effect of separase depletion on ionizing radiation-induced cell cycle checkpoints and survival in human lung cancer cell lines

(2008) A. Sak et al.   CELL PROLIFERATION

Separase cooperates with Zds1 and Zds2 to activate Cdc14 phosphatase in early anaphase

(2008) Ethel Queralt et al.   JOURNAL OF CELL BIOLOGY

Overexpression of Separase induces aneuploidy and mammary tumorigenesis

(2008) N. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibitory Phosphorylation of Separase Is Essential for Genome Stability and Viability of Murine Embryonic Germ Cells

(2008) Xingxu Huang et al.   PLOS BIOLOGY