Article
Radiology, Nuclear Medicine & Medical Imaging
Mohamad Alissa, Klemens Zink, Frederic Tessier, Andreas A. Schoenfeld, Damian Czarnecki
Summary: This study aimed to calculate beam quality correction factors kQ for SNC600c and SNC125c ionization chambers, comparing the results with published kQ values for similar chambers, demonstrating a high level of agreement.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2022)
Article
Engineering, Biomedical
Yuka Urago, Makoto Sakama, Dousatsu Sakata, Shigekazu Fukuda, Tetsurou Katayose, Weishan Chang
Summary: In this study, kQ values were calculated in four cylindrical chambers and two plane-parallel chambers using Monte Carlo simulations. The calculated kQ ratios were validated through comparisons against measured values. The kQ uncertainty was reduced from 3% to 1.7%, and the P values varied between different chamber types.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Cameron Dennis Pain, Graeme Joseph O'Keefe, Andrew Mark Scott
Summary: A method for calculating NMIC calibration settings using Monte Carlo modeling has been developed and validated against physical measurements. This method allows for a wider range of isotopes and provides more detailed calibration parameter specifications.
Article
Radiology, Nuclear Medicine & Medical Imaging
Mohamad Alissa, Klemens Zink, Ralf-Peter Kapsch, Andreas A. A. Schoenfeld, Stephan Frick, Damian Czarnecki
Summary: This study aimed to determine the correction factors kB,Q for ion chambers in the presence of external magnetic fields in high-energy photon fields. The results showed that the magnitude of the correction factor depends on the chamber volume and orientation, and the preferred chamber orientation is when the magnetic field direction and the chamber axis coincide and are perpendicular to the beam direction. The correction factors can be applied in clinical reference dosimetry for existing MRI-linear accelerators.
Article
Radiology, Nuclear Medicine & Medical Imaging
Miguel Lopez-Sanchez, Maria Perez-Fernandez, Eduardo Pardo, Jose M. Fandino, Antonio Teijeiro, Nicolas Gomez-Fernandez, Faustino Gomez, Diego M. Gonzalez-Castano
Summary: This study used Monte Carlo simulation to evaluate the response of the four smallest active volume ionization chambers when measuring SRS cone collimated FFF fields. The IBA RAZOR Nano Chamber was found to be an excellent choice for narrow beam output factor measurement due to its minimum correction requirement and advantages of tiny size and tissue equivalence materials.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2022)
Article
Chemistry, Physical
Laura Weiler, Tina N. Mihm, James J. Shepherd
Summary: This article introduces a Gaussian process regression model for the transition structure factor in metal periodic coupled cluster singles and doubles calculations. The model is inspired by previous methods and uses a one-dimensional function to fit the structure factor and correct for finite size errors.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Chemistry, Physical
Wei Wan, Changxin Tang, Wennan Zou
Summary: This study used a high efficient MC/MD approach to reproduce silicon [001] small angle symmetric tilt grain boundaries, focusing on the variations of grain boundary properties under different misorientation angles and the roles of dislocation stress fields in shaping special grain boundary properties. Calculations of key parameters for grain boundary structures and energies were conducted, which could benefit future grain boundary engineering.
APPLIED SURFACE SCIENCE
(2022)
Article
Green & Sustainable Science & Technology
Luca Prattico, Nicola Fronza, Ruben Bartali, Andrea Chiappini, Enrico Sciubba, J. Gonzalez-Aguilar, Luigi Crema
Summary: This work introduces a new methodology for the 3D optical-performance analysis of volumetric solar receivers with an open hierarchical structure. The experimental technique proposed in this study shows promise as a robust in operando method for characterizing radiation propagation within complex porous structures used in volumetric receivers.
Article
Chemistry, Physical
Lingli Mao, Xi Pei, Tsi-Chian Chao, Xie George Xu
Summary: This study aimed to calculate the magnetic field correction factor kB for cylindrical ionization chambers and investigate the impact of orientations and beam energies on kB under different magnetic field strengths. The results indicated that kB values varied with different configurations and magnetic field strengths, and the beam energy also affected the kB values.
RADIATION PHYSICS AND CHEMISTRY
(2021)
Article
Engineering, Biomedical
L. I. Ramos Garcia, J. F. Perez-Azorin, M. Anguiano, A. M. Lallena
Summary: In this study, a Monte Carlo scheme is proposed to calculate the collection efficiency for any ionization chamber geometry. Results show that the method is stable against changes in different parameters and can be a useful tool for calculating collection efficiencies of ionization chambers.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Nuclear Science & Technology
Dean Price, Brendan Kochunas
Summary: In the field of nuclear engineering, linear regression-based analyses are commonly used to study relationships between model parameters and responses of interest in complex systems. This paper explores the impact of Monte Carlo error on the error of computed linear regression coefficients for the response of interest. The study demonstrates that under certain conditions, the error in regression coefficients can be largely independent of the Monte Carlo error in individual calculations.
NUCLEAR ENGINEERING AND TECHNOLOGY
(2022)
Article
Materials Science, Coatings & Films
Zhiping Wang, Zhe Wang, Tao Zhang, Wansen Guo, Huwei Dai, Kunying Ding
Summary: This study assesses the reliability of thermal barrier coatings using a Monte-Carlo simulation-based method and finds that there is a risk of failure in thermal barrier coatings under high-temperature airflow conditions, with reliability influenced by temperature and TGO development.
SURFACE & COATINGS TECHNOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Kilian-Simon Baumann, Carles Goma, Joerg Wulff, Jana Kretschmer, Klemens Zink
Summary: This study calculates global ionization chamber factors (fQ) and beam quality correction factors (kQ) for air-filled ionization chambers in clinical proton beams using different Monte Carlo codes. The average Monte Carlo calculated fQ and kQ factors are provided, and the uncertainty of these factors is estimated. Comparison shows that the Monte Carlo calculated fQ factors differ from the values in the IAEA TRS-398 CoP, while the uncertainty of the Monte Carlo calculated kQ factors is smaller.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2023)
Article
Environmental Sciences
Jian Yang, Yue Ma, Huiying Zheng, Yuanfei Gu, Hui Zhou, Song Li
Summary: The study quantitatively models and analyzes the forward-scattering effect on spaceborne photon-counting lidar bathymetry and proposes an empirical formula for correcting the bathymetric bias specific to ICESat-2. The research finds that the bias cannot be neglected for ICESat-2 even in clear open ocean waters when the water depth exceeds 20 m. The proposed formula successfully corrects the bathymetric bias in deep waters, reducing it from exceeding 50 cm to less than 13 cm in two study areas.
Article
Physics, Multidisciplinary
Julian Roers, Damian Czarnecki, Mohamad Alissa, Klemens Zink
Summary: The aim of this study is to investigate the depth-dependent detector response of detailed thimble air-filled ionization chambers. Spectral charged particle fluence correction factors at different depths were calculated to analyze the variations in detector response and the influences of different effects on the spectral response.
FRONTIERS IN PHYSICS
(2023)
Article
Engineering, Biomedical
Kilian-Simon Baumann, Larissa Derksen, Matthias Witt, Jan Michael Burg, Rita Engenhart-Cabillic, Klemens Zink
Summary: This study provides Monte Carlo calculated beam quality correction factors for monoenergetic proton beams and compared them with experimentally determined values, showing good agreement at the 1% level, with a need for further investigation of differences between Monte Carlo codes for high energies.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Engineering, Biomedical
Veronika Flatten, Jan Michael Burg, Matthias Witt, Larissa Derksen, Pedro Fragoso Costa, Joerg Wulff, Christian Baeumer, Beate Timmermann, Uli Weber, Hilke Vorwerk, Rita Engenhart-Cabillic, Klemens Zink, Kilian-Simon Baumann
Summary: This study examined the impact of lung tissue heterogeneity on the Bragg peak curve through CT histogram analysis, and developed a new method to estimate the effect of materials or specific regions on the BP based on common clinical CT images. The model was validated for organic samples, demonstrating its effectiveness in predicting BP degradation.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Engineering, Biomedical
Larissa Derksen, Tabea Pfuhl, Rita Engenhart-Cabillic, Klemens Zink, Kilian-Simon Baumann
Summary: This study aimed to investigate the feasibility of using TOPAS-nBio for track structure simulations by re-simulating GEANT4-DNA example applications and studying low-energy electron interactions. The results showed good agreement with GEANT4-DNA simulations.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Athena Evalour Simbahon Paz, Kilian-Simon Baumann, Uli Andreas Weber, Matthias Witt, Klemens Zink, Marco Durante, Christian Graeff
Summary: This study focused on predicting and mitigating the degradation in physical and biological dose distributions of particle beams caused by microscopic heterogeneities in lung tissue. The TRiP98 treatment planning system was adapted to account for the beam-modulating effect of heterogeneous lung tissue. Experimental results showed the effectiveness of the implementation in compensating for lung dose perturbations, with potential implications for improving treatment outcomes in lung cancer patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Mohamad Alissa, Klemens Zink, Frederic Tessier, Andreas A. Schoenfeld, Damian Czarnecki
Summary: This study aimed to calculate beam quality correction factors kQ for SNC600c and SNC125c ionization chambers, comparing the results with published kQ values for similar chambers, demonstrating a high level of agreement.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Thomas Failing, Gunther H. Hartmann, Frank W. Hensley, Boris Keil, Klemens Zink
Summary: Simulation of absorbed dose deposition in a detector is crucial for Monte Carlo dosimetry, and recent research has shown that upgrading codes can significantly enhance efficiency. The modified egs_chamber code provides accurate charged particle fluence spectra calculations, demonstrating feasibility and efficiency gains in simulations.
ZEITSCHRIFT FUR MEDIZINISCHE PHYSIK
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yuri Simeonov, Uli Weber, Christoph Schuy, Rita Engenhart-Cabillic, Petar Penchev, Veronika Flatten, Klemens Zink
Summary: The study aimed to develop and manufacture a 3D range-modulator for scanned proton therapy, which showed promising results in producing highly homogeneous dose distributions that are comparable to standard IMPT. Monte Carlo simulations were used to investigate its modulating properties and dose distribution, and the results were validated with measurements at a treatment center. The concept of the 3D range-modulator combines high dose homogeneity and conformity with very short irradiation times, providing a clinically applicable dose distribution for lung and/or FLASH treatment.
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Stephanie Schade, Rita Engenhart-Cabillic, Klemens Zink, Damian Czarnecki
Summary: This study developed an algorithm to correct the image of an electronic portal imaging device (EPID) for dosimetric purposes, investigating the impact of field size, phantom thickness, and spectral photon distribution on the EPID image. The algorithm showed promising results in correcting these influences and enabling high-precision dose measurements. By using multiple correction factors, the EPID image can be easily adjusted for other linear accelerators and configurations.
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Damian Czarnecki, Klemens Zink, Mohamad Alissa, Veronika Flatten, Teresa Espelage, Andreas A. Schoenfeld
Summary: This study investigated the ability of the IC Profiler detector array to measure photon beam quality and developed a Monte Carlo-based model for validation. The results showed that the Monte Carlo simulations were consistent with the measurements, demonstrating the reliability of the model. Furthermore, the model can be used for further research on the effects of beam parameter variations on AR ratios and %dd(10)x$_\textrm {{\it x}}$.
Article
Radiology, Nuclear Medicine & Medical Imaging
Leon Baack, Christoph Schuy, Stephan Brons, Felix Horst, Bernd Voss, Klemens Zink, Thomas Haberer, Marco Durante, Uli Weber
Summary: This study investigates the recombination loss of different fill gases in plane parallel ionisation chambers and develops a numerical model for simulating the space charge effect. The results show that He/CO2 mixtures allow accurate beam monitoring at high intensities, and adding CO2 decreases ion mobility but increases breakdown voltage.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2022)
Article
Physics, Multidisciplinary
Julian Roers, Damian Czarnecki, Mohamad Alissa, Klemens Zink
Summary: The aim of this study is to investigate the depth-dependent detector response of detailed thimble air-filled ionization chambers. Spectral charged particle fluence correction factors at different depths were calculated to analyze the variations in detector response and the influences of different effects on the spectral response.
FRONTIERS IN PHYSICS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mohamad Alissa, Klemens Zink, Ralf-Peter Kapsch, Andreas A. A. Schoenfeld, Stephan Frick, Damian Czarnecki
Summary: This study aimed to determine the correction factors kB,Q for ion chambers in the presence of external magnetic fields in high-energy photon fields. The results showed that the magnitude of the correction factor depends on the chamber volume and orientation, and the preferred chamber orientation is when the magnetic field direction and the chamber axis coincide and are perpendicular to the beam direction. The correction factors can be applied in clinical reference dosimetry for existing MRI-linear accelerators.
Article
Engineering, Biomedical
Larissa Derksen, Veronika Flatten, Rita Engenhart-Cabillic, Klemens Zink, Kilian-Simon Baumann
Summary: In this study, the authors used Monte Carlo track structure simulations to investigate the effect of inter-track interactions on the yield of chemicals produced by ionizing particles. The results suggest that inter-track interactions may explain the reduced normal tissue toxicity observed in FLASH radiotherapy.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jan Michael Burg, Veronika Flatten, Joerg Wulff, Beate Timmermann, Hilke Vorwerk, Klemens Zink
Summary: It has been discovered that water and PMMA emit a weak luminescence signal when irradiated with protons within the clinically used energy range. A setup for high-resolution spectral measurement of the luminescence signal in water and PMMA was designed in this work. The results show that the signal originates from excited states produced during the radiolysis of water and there are differences in the spectra between water and PMMA. The findings provide a foundation for further research on proton range verification.
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS
(2023)
Article
Engineering, Biomedical
Kilian-Simon Baumann, Larissa Derksen, Matthias Witt, Sebastian Adeberg, Klemens Zink
Summary: This study investigates the influence of different versions of the Monte Carlo codes geant4 and fluka on the calculation of overall response functions f(Q) of air-filled ionization chambers in clinical proton beams. The results show that there can be differences of up to 1% in the f(Q) factors calculated with different versions of the same Monte Carlo code. The updated version of geant4 leads to a more pronounced dependence of f(Q) on proton energy and smaller f(Q) factors for high energies.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)