Article
Environmental Sciences
Ebru Icoz, Fasih M. Malik, Kutay Icoz
Summary: Air pollution is a global issue, with particulate matter being a significant pollutant. Studies have shown the lethal impact of particulate matter on public health and environment, linked to various health problems. The current air quality monitoring systems are costly and have limited spatial resolution. The study developed a portable, low-cost, and cloud-integrated particulate matter measurement system.
ENVIRONMENTAL AND ECOLOGICAL STATISTICS
(2021)
Article
Computer Science, Artificial Intelligence
Van Hiep Pham, Van Tu Nguyen, Cao Duong Ly, Jaeyeop Choi, Sumin Park, Sudip Mondal, Tan Hung Vo, Hae Gyun Lim, Junghwan Oh
Summary: This article reports a low-cost fast dual photoacoustic and ultrasound imaging system (F-PAUSM) based on custom-made slider-crank and ball-screw mechanisms. The system allows stable capture of wide scanning ranges and demonstrates potential applications in biomedical imaging.
EXPERT SYSTEMS WITH APPLICATIONS
(2022)
Article
Engineering, Biomedical
Youfang Lai, Qian Wang, Shiwei Zhou, Zhaoheng Xie, Jinyi Qi, Simon R. Cherry, Mingwu Jin, Yujie Chi, Junwei Du
Summary: This study simulated and compared four total-body small-animal PET systems in terms of spatial resolution and sensitivity, finding that all scanners had a spatial resolution better than 0.5 mm at the center of the FOV, with radial resolution depending on DOI resolution and radial offset. The C10 design provided better resolution, while the C20 design had higher sensitivity. For cost-effective total-body mouse studies, the 110 mm systems are a good choice, while the 160 mm systems are suited for both total-body mouse and rat studies.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Chemistry, Analytical
Regina G. Oliveira, Pedro M. M. Correia, Ana L. M. Silva, Pedro M. C. C. Encarnacao, Fabiana M. Ribeiro, Ismael F. Castro, Joao F. C. A. Veloso
Summary: Monitoring the vital signs of mice is crucial for imaging procedures. This study developed a sensor-based monitoring system and validated its reliability through comparison with literature results. Additionally, a non-invasive electrocardiogram module was developed, showing integration potential with the system.
Article
Acoustics
Saba Rahimi, Ryan Matthew Jones, Kullervo Hynynen
Summary: This study presents a high-frequency phased array system for transcranial FUS delivery in small animals, utilizing 64 independent elements of equal surface area for beamforming and focusing capabilities. The array can electronically steer the FUS beam and restore partial focal quality through phase corrections, enabling microbubble-mediated blood-brain barrier permeabilization at similar to 2.0 MPa peak negative focal pressure when targeting through a rat skullcap.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2021)
Article
Chemistry, Analytical
Shih-Po Su, Syue-Liang Lin, Yang-Hsiang Chan, Yi-Jang Lee, Yun-Chen Lee, Pin-Xuan Zeng, Yi-Xuan Li, Muh-Hwa Yang, Huihua Kenny Chiang
Summary: Near-infrared-II (NIR-II) fluorescence imaging offers high spatial resolution and deep tissue penetration for visualization of blood vessels and tumors in deep tissue. In this study, a stereo NIR-II fluorescence imaging system was developed, along with fluorescent semiconducting polymer dots with ultra-bright NIR-II fluorescence for long-term imaging. The system successfully obtained high-resolution 3D blood vessel images.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ming Niu, Zheng Liu, Zhonghua Kuang, Xiaohui Wang, Ning Ren, Ziru Sang, San Wu, Longhan Cong, Tao Sun, Zhanli Hu, Yongfeng Yang
Summary: This study aims to develop high-efficiency and ultra-high-resolution detectors for small animal PET scanners with high sensitivity and spatial resolution approaching the physical limit.
Article
Computer Science, Information Systems
Jie Zhao, Qiong Liu, Chaofan Li, Yunfeng Song, Ying Zhang, Jyh-Cheng Chen
Summary: The aim of this study was to optimize the image quality in an iterative reconstruction algorithm for the small-animal Metis PET/CT system through evaluation using a homemade phantom and a healthy mouse study. The results indicate that optimizing spatial resolution and choosing appropriate reconstruction parameters and post-filter FWHM can achieve high-resolution images and quantitative accuracy.
Article
Environmental Sciences
Paul Berg, Deise Santana Maia, Minh-Tan Pham, Sebastien Lefevre
Summary: In this article, a modification of the patch distribution modeling method (PaDiM) is proposed for weakly supervised detection of marine animals. Comparative evaluation on two high-resolution marine animal image datasets demonstrates that the proposed method achieves better detection results when trained on images without objects of interest, indicating its potential for speeding up the discovery of marine animals in new flight surveys.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kazunari Ishii, Kohei Hanaoka, Shota Watanabe, Daisuke Morimoto-Ishikawa, Takahiro Yamada, Hayato Kaida, Yoshiyuki Yamakawa, Suzuka Minagawa, Shiho Takenouchi, Atsushi Ohtani, Tetsuro Mizuta
Summary: This study compared the clinical superiority of dhPET and wbPET systems in acquiring brain images. The dhPET images were visually better and had higher SUVRs than wbPET images. Although there were regional accumulation differences, understanding this phenomenon will enhance the clinical use of the dhPET system.
JOURNAL OF NUCLEAR MEDICINE
(2023)
Article
Engineering, Biomedical
Xinyi Cheng, Kun Hu, Dongxu Yang, Yiping Shao
Summary: The compact and lightweight PET technology is designed to provide functional/biological/molecular imaging for preclinical radiation therapy research, demonstrating sufficient capability and performance.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Environmental Sciences
Dong Chen, Tatiana Loboda, Julie A. Silva, Maria R. Tonellato
Summary: The study successfully mapped the buildings and corrals of two remote villages in Mozambique using high resolution imagery and locally adjusted classification algorithms, demonstrating the potential of this approach. The comparison of mapping results revealed improvements in the economic status of both villages, despite their differences.
Article
Radiology, Nuclear Medicine & Medical Imaging
Han Gyu Kang, Hideaki Tashima, Hidekatsu Wakizaka, Fumihiko Nishikido, Makoto Higuchi, Miwako Takahashi, Taiga Yamaya
Summary: The ultrahigh-resolution small-animal PET scanner we developed can provide a resolution approaching 0.6 mm, allowing for unprecedented visualization of mouse brain function. It consists of 4 rings with 16 depth-of-interaction detectors each, and has shown promising results for neuroscience research using rodent models.
JOURNAL OF NUCLEAR MEDICINE
(2023)
Article
Engineering, Electrical & Electronic
Chaehyun Kim, Ahram Jang, Sebin Kim, Sungbo Cho, Donghun Lee, Young-Joon Kim
Summary: In this study, a simple and minimally invasive ECG measurement system for mice was developed. It consists of a miniaturized wearable ECG monitoring device and a smartphone application that displays real-time ECG waveform and heart rate. The system proved to be feasible through validation experiments.
IEEE SENSORS JOURNAL
(2023)
Article
Geochemistry & Geophysics
Yuqi Wang, Guang-Cai Sun, Yong Wang, Zijing Zhang, Mengdao Xing, Xiaoniu Yang
Summary: The paper introduces a novel passive positioning system called Synthetic Aperture Positioning (SAP) system to improve accuracy by addressing the issue of nonlinear initial phase caused by the nonlinear variation of viewing angles over a long duration, especially in low signal-to-noise ratio (SNR) situations.
IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yuwei Liu, Tadashi Watabe, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Sadahiro Naka, Kazuhiro Ooe, Atsushi Toyoshima, Kojiro Nagata, Uwe Haberkorn, Clemens Kratochwil, Atsushi Shinohara, Jun Hatazawa, Frederik Giesel
Summary: This study suggests the potential application of FAPI radioligand therapy in FAP-expressing pancreatic cancer, but further evaluation is needed to identify the best radionuclide with a shorter half-life, as well as combination with therapies targeting tumor cells directly.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Kazuhiro Kitajima, Tadashi Watabe, Masatoyo Nakajo, Mana Ishibashi, Hiromitsu Daisaki, Fumihiko Soeda, Atsushi Tanemura, Takuro Kanekura, Naoya Yamazaki, Kimiteru Ito
Summary: In malignant melanoma patients, different FDG-PET criteria (EORTC, PERCIST, imPERCIST) showed accuracy for response evaluation of ICI therapy and prediction of patient prognosis. Responders (CMR/PMR) had significantly longer PFS and OS compared to non-responders (SMD/PMD).
JAPANESE JOURNAL OF RADIOLOGY
(2022)
Article
Multidisciplinary Sciences
Akihisa Omata, Miho Masubuchi, Nanase Koshikawa, Jun Kataoka, Hiroki Kato, Atsushi Toyoshima, Takahiro Teramoto, Kazuhiro Ooe, Yuwei Liu, Keiko Matsunaga, Takashi Kamiya, Tadashi Watabe, Eku Shimosegawa, Jun Hatazawa
Summary: X-ray and gamma-ray imaging technologies are crucial for radiological diagnosis and radionuclide therapy. Single-photon emission tomography (SPECT) and positron emission tomography (PET) play essential roles in early tumor detection. Researchers have developed a hybrid Compton camera that allows simultaneous Compton and pinhole imaging within a single system. In this study, they achieved simultaneous imaging of different modalities including Compton, pinhole, and PET using multiple hybrid Compton cameras in 3D space.
SCIENTIFIC REPORTS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sadahiro Naka, Toshimitsu Watanabe, Yasukazu Kanai, Tadashi Watabe, Mitsuaki Tatsumi, Hiroki Kato, Eku Shimosegawa, Jun Hatazawa
Summary: We developed a stable and practical method for the synthesis of [F-18]FBPA, which is more practical compared to the method using [O-18]O-2 gas recycling and [F-18]F-2 labeling agent.
NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Nuclear Science & Technology
Hiroshi Watabe, Kwan Ngok Yu, Nursel Safakatti, Mehrdad Shahmohammadi Beni
Summary: The Monte Carlo (MC) method is essential in nuclear radiation research, and we have developed an open-source GUI computer program for radiation transport and interaction modeling using the PHITS MC package in segmented slab phantoms. This program is useful for future users, especially those with less experience in the PHITS MC package.
NUCLEAR ENGINEERING AND TECHNOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tadashi Watabe, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Kazuhiro Ooe, Yang Wang, Hiromitsu Haba, Atsushi Toyoshima, Jens Cardinale, Frederik L. Giesel, Noriyuki Tomiyama, Koichi Fukase
Summary: This study evaluated the treatment effect of At-211-labeled PSMA compounds in mouse xenograft models. The results showed that TAT using [At-211]PSMA5 resulted in excellent tumor growth suppression with minimal side effects, suggesting it as a potential new treatment for metastatic CRPC.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Biochemistry & Molecular Biology
N. M. B. Sathee, M. Mousumi Khatun, Anita Rani, M. Masum Billah, M. Nure Alam Abdullah, Mahmudul H. Khandker, Hiroshi Watabe, A. K. Fazlul Haque, M. Alfaz Uddin
Summary: This study investigates the theoretical scattering of electrons and positrons by the ethane (C2H6) molecule, considering the screening correction through semiclassical analysis. Various observable quantities, including differential, integrated elastic, momentum transfer, viscosity, inelastic, grand total, total ionization cross-sections, and Sherman functions, are calculated using the independent atom approximation. A comparative study is conducted between electron and positron impact to reveal the differences in the collisions. The results are compared with existing experimental and theoretical works, and the effect of screening correction is found to be significant.
Article
Multidisciplinary Sciences
Danni Ramdhani, Nita Listiani, Maula Eka Sriyani, W. Eva Maria, Hiroshi Watabe, Resmi Mustarichie, Sri Agung Fitri Kusuma, Regaputra S. Janitra
Summary: This research evaluated the physicochemical characteristics of the [Tc-99m]Tc-genistein complex and described the optimal labeling method parameters. The results showed that [Tc-99m]Tc-genistein had a high radiochemical purity and good physicochemical properties. DFT calculations also confirmed the stability of the Tc(IV)-genistein complex. Therefore, [Tc-99m]Tc-genistein could be a potential radiotracer kit for SPECT imaging of breast cancer.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Tadashi Watabe, Takahito Fukusumi, Hidenori Inohara, Mitsuaki Tatsumi, Sadahiro Naka, Takashi Kamiya, Hiroki Kato, Yuriko Mori, Jens Cardinale, Frederik L. Giesel
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Biochemistry & Molecular Biology
Ayaka Aso, Hinako Nabetani, Yoshifumi Matsuura, Yuichiro Kadonaga, Yoshifumi Shirakami, Tadashi Watabe, Taku Yoshiya, Masayoshi Mochizuki, Kazuhiro Ooe, Atsuko Kawakami, Naoya Jinno, Atsushi Toyoshima, Hiromitsu Haba, Yang Wang, Jens Cardinale, Frederik Lars Giesel, Atsushi Shimoyama, Kazuko Kaneda-Nakashima, Koichi Fukase
Summary: In this study, four novel At-211-FAPI(s) with PEG linkers were designed and synthesized, and their FAP selectivity and uptake were tested. The results showed that PEG linkers had equivalent antitumor effects to PIP linkers, indicating that PEG linkers can serve as alternatives to PIP linkers.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Engineering, Biomedical
Seiichi Yamamoto, Hiroshi Watabe, Kohei Nakanishi, Takuya Yabe, Mitsutaka Yamaguchi, Naoki Kawachi, Kei Kamada, Akira Yoshikawa, Md Rafiqul Islam, Masayasu Miyake, Kazuo S. Tanaka, Jun Kataoka
Summary: This study successfully conducted imaging of prompt x-rays and induced positrons using a low-energy X-ray camera. This imaging method can compensate for the limited imaging capability of existing systems and can be used to estimate the shape of proton beams and the distribution and time activity curves of induced positrons.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)
Article
Physics, Atomic, Molecular & Chemical
Sunzida Parvin, M. Masum Billah, Mahmudul H. H. Khandker, M. Ismail Hossain, M. M. Haque, Mehrdad Shahmohammadi Beni, Hiroshi Watabe, A. K. Fazlul Haque, M. Alfaz Uddin
Summary: This article presents a detailed calculation of observable quantities for the scattering of electrons and positrons on a post-transition metal Thallium (Tl) using relativistic Dirac partial wave analysis. The study includes various cross sections and analyses of collision dynamics, such as spin asymmetry and interference effects. The results are compared with previous experimental and theoretical findings to assess the performance of the approach.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Tadashi Watabe, Ivan Ray David, Toru Kimura, Takashi Hiroshima, Mitsuaki Tatsumi, Sadahiro Naka, Takashi Kamiya, Eriko Fukui, Takashi Kanou, Naoko Ose, Soichiro Funaki, Yuriko Mori, Jens Cardinale, Hiroki Kato, Eiichi Morii, Yasushi Shintani, Frederik L. Giesel
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Optics
Pretam K. Das, G. B. Ragimkhanov, Z. R. Khalikova, M. Shorifuddoza, M. Moniruddoza Ashir, Joydeb Barman, Hiroshi Watabe, A. K. Fazlul Haque, M. Alfaz Uddin
Summary: This work presents the results of differential and various angle integrated cross sections for electron and positron scattering by silicon atoms. It also calculates the Sherman function S(theta) and two other spin asymmetry parameters U(theta) and T(theta). Critical minima in elastic differential cross sections and maximum spin polarization points were identified for this element. The research utilizes the Dirac partial wave method with a complex optical model potential. Additionally, the study calculates the transport characteristics of electrons in silicon vapors and mixtures of inert gases using the Monte Carlo method.
EUROPEAN PHYSICAL JOURNAL D
(2023)
Article
Environmental Sciences
Hiroshi Watabe, Tatsuhiko Sato, Kwan Ngok Yu, Milena Zivkovic, Dragana Krstic, Dragoslav Nikezic, Kyeong Min Kim, Taiga Yamaya, Naoki Kawachi, Hiroki Tanaka, A. K. F. Haque, M. Rafiqul Islam, Mehrdad Shahmohammadi Beni
Summary: This article introduces the extended application of the DynamicMC software in combination with the PHITS code to model the dynamic movement of an anthropomorphic phantom. By implementing four new functions, the software provides higher flexibility and computational efficiency, benefiting the research and teaching of nuclear radiation physics.
RADIATION PROTECTION DOSIMETRY
(2023)