Article
Hospitality, Leisure, Sport & Tourism
Hajo Thermann, Ralph Fischer, Nikolaos Gougoulias, Lucio Cipollaro, Nicola Maffulli
Summary: Surgery may be necessary when conservative treatment does not improve symptoms in patients with non-insertional Achilles tendinopathy. This study found that endoscopic debridement of the Achilles tendon improved clinical outcomes, and the addition of PRP did not provide any additional benefits. MRI parameters were not correlated with clinical outcomes.
JOURNAL OF SPORT AND HEALTH SCIENCE
(2023)
Review
Chemistry, Multidisciplinary
Dawid Szwedowski, Lukasz Jaworski, Wioleta Szwedowska, Przemyslaw Pekala, Maciej Gagat
Summary: Neovascularization is a complex process involving multiple steps, with abundant neovascularization being found in tendinous tissue of asymptomatic athletes or early after injury. In musculoskeletal disorders, this process seems to be associated with pain and poor clinical outcomes. Reviewing the literature aims to investigate the role of neovascularization in tendon and meniscus injuries and its potential as a target in therapies like PRP.
APPLIED SCIENCES-BASEL
(2021)
Article
Cell Biology
Jianguo Chen, Yingying Wan, Haiyue Jiang
Summary: Current evidence on the effectiveness of PRP for ATR or AT is limited to small-sized trials. PRP injection may lead to a higher improvement in VISA-A score for AT patients at 6 weeks but shows no significant difference at later follow-ups. There is no significant difference in outcomes between PRP and control groups for ATR patients at different follow-up time points.
Article
Multidisciplinary Sciences
Jianying Zhang, Feng Li, Tyler Augi, Kelly M. Williamson, Kentaro Onishi, MaCalus Hogan, Matthew D. Neal, James H-C Wang
Summary: Platelet-rich plasma (PRP) containing PLT HMGB1 plays a crucial role in tendon wound healing by reducing inflammation, increasing local HMGB1 levels, and recruiting stem cells to the injured area. The efficacy of PRP treatment for tendon injuries in clinics may be dependent on the presence of PLT HMGB1 in PRP preparations.
Review
Rehabilitation
Ian Burton
Summary: This scoping review mapped existing evidence on prevention and in-season management interventions for patellar tendinopathy (PT) in athletes. The review found that resistance training, including eccentric, heavy slow, and isometric training, may be a useful prophylactic method. However, there is a lack of studies on ESWT and other interventions.
PHYSICAL THERAPY IN SPORT
(2022)
Review
Medicine, Research & Experimental
Xueli Liu, Rong Zhang, Bin Zhu, Yujie Li, Xinyue Liu, Sheng Guo, Chenglong Wang, Dingxuan Wang, Sen Li
Summary: Platelet-rich plasma (PRP) has shown promising effects in treating tendon disorders by reducing pain, improving function, and promoting tendon healing. However, the role of leukocytes in PRP depends on the biological state of the injured tissue, leading to varying effects at different stages of tendon repair.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2021)
Article
Health Care Sciences & Services
Kim Loose, Sophie Pennekamp, Wolfgang Hitzl, Maximilian Willauschus, Johannes Ruether, Sandeep Silawal, Philipp Schuster, Hermann Josef Bail, Michael Millrose, Markus Gesslein
Summary: In this retrospective study, patients with patellar tendinopathy (PT) were compared with a control group in terms of patient data and MRI characteristics. The study found significant differences in patellar height and patella-patellar tendon angle between the PT patient group and the control group. The thickness of different parts of the patellar tendon was also significantly increased in patients with PT. Persistence of symptoms over 6 months was associated with increased signal intensity in MRI. These findings can help in understanding PT and identifying suitable surgical candidates.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Julien Ghelfi, Marylene Bacle, Olivier Stephanov, Helene de Forges, Ian Soulairol, Pascal Roger, Gilbert R. Ferretti, Jean-Paul Beregi, Julien Frandon
Summary: The study successfully developed a new large animal model for studying patellar tendinopathy with neovascularization. After collagenase injection, tendons enlarged and new vessels formed, showing a dose-related correlation with collagenase dose.
Article
Sport Sciences
Kyungmi Park, Joyce H. Keyak, Kornelia Kulig, Christopher M. Powers
Summary: This study aimed to compare peak maximum principal stress in the patellar tendon between persons with and without patellar tendinopathy during a simulated single-leg landing task. The study found that individuals with patellar tendinopathy had higher peak maximum principal stress in the patellar tendon and were more affected by tibiofemoral rotation.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Editorial Material
Orthopedics
James B. Carr
Summary: PRP injections are increasingly used to treat musculoskeletal conditions, with evidence supporting their positive effects on soft tissue healing. While PRP has shown benefits for knee osteoarthritis, research on its efficacy for shoulder conditions is limited. The high concentration of growth factors and inflammatory modulators in PRP may aid in tendon regeneration and healing, making it an appealing treatment option for conditions like partial-thickness rotator cuff tears and tendinopathy.
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
(2021)
Review
Biotechnology & Applied Microbiology
Jialin Lu, Han Li, Ziyu Zhang, Rui Xu, Jincheng Wang, Hui Jin
Summary: Tendinopathy is a medical condition characterized by inflammatory and degenerative changes in tendons due to trauma or overuse. Platelet-rich plasma (PRP) is a promising therapeutic agent for tendinopathy, as it can promote cell proliferation and differentiation, regulate angiogenesis, increase extracellular matrix synthesis, and modulate inflammation in degenerative tendons.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Orthopedics
Long Pang, Tao Li, Yinghao Li, Yang Xu, Jing Zhu, Xin Tang
Summary: The purpose of this study was to investigate whether platelet-rich plasma (PRP) injection can be an alternative to corticosteroid (CS) injection for conservative treatment of rotator cuff disease. The results showed that PRP provided worse short-term changes in assessment scores, but better medium-term and long-term changes in various scores compared to CS. PRP injections led to worse short-term changes in some movements but better medium-term changes in others. PRP injection showed lower rates of post-injection failure compared to CS. PRP injection may reduce rates of subsequent injection or surgery and provide better improvements in pain and function in the medium to long term.
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
(2023)
Article
Medicine, General & Internal
Yusuke Nishida, Tomofumi Nishino, Kenta Tanaka, Shinzo Onishi, Akihiro Kanamori, Masashi Yamazaki
Summary: This study aimed to investigate an objective measure of patellar tendon thickness and found that defining thickening of the patellar tendon as greater than 7.0 mm on both ultrasonography and MRI can serve as an accurate predictor of clinical patellar tendinopathy.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Sabino Padilla, Mikel Sanchez, Victor Vaquerizo, Gerard A. Malanga, Nicolas Fiz, Juan Azofra, Christopher J. Rogers, Gonzalo Samitier, Steven Sampson, Roberto Seijas, Ricardo Elorriaga, Jack Taunton, Frank Boehm, Roberto Prado, Ramon Cugat, Eduardo Anitua
Summary: PRP serves as an attractive adjunct treatment for Achilles tendon ruptures, but the myriad preparation methods and lack of standardization in application modalities are the main weaknesses affecting its consistent effectiveness.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Medicine, General & Internal
Chun-Yu Hung, Shih-Jie Lin, Chia-Yi Yeh, Wen-Ling Yeh
Summary: This study evaluated the effectiveness of PRP in patients with acute Achilles tendon rupture. The results showed that PRP augmentation in Achilles tendon surgery did not lead to superior functional and clinical outcomes. Clinicians should provide accurate information regarding PRP treatment to patients undergoing Achilles tendon surgery.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Linda Lecker, Martin Stevens, Florian Thienel, Djordje Lazovic, Inge Van den Akker-Scheek, Gesine H. Seeber
Summary: To improve diabetic foot syndrome prevention, a valid and reliable instrument for measuring daily foot-care routines in patients with diabetes is needed. This study translated and adapted the Diabetic Foot Self-Care Behavior Scale into German, and evaluated its validity and reliability.
Correction
Orthopedics
R. Deviandri, H. C. van der Veen, A. M. T. Lubis, I. van den Akker-Scheek, M. J. Postma
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Review
Orthopedics
R. Deviandri, H. C. van der Veen, A. M. T. Lubis, I Van den Akker-Scheek, M. J. Postma
Summary: This study systematically reviewed health-economic evaluations of anterior cruciate ligament (ACL) injury and compared the cost-effectiveness of reconstruction surgery (ACLR) and non-operative treatment (NO). The results suggest that early ACLR may be the more cost-effective strategy for athletes and young populations with high-activity levels, while non-operative treatment with optional delayed ACLR may be more cost-effective. However, for middle-aged individuals with moderate activity levels, early ACLR may not be more cost-effective than delayed ACLR.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Review
Orthopedics
H. W. van Kouswijk, H. G. van Keeken, J. J. W. Ploegmakers, G. H. Seeber, I. van den Akker-scheek
Summary: A systematic review found that exercise interventions after lower limb-salvage surgery (LSS) for sarcoma have low therapeutic validity and effectiveness. Further research is needed. Evaluatiom: 7 out of 10.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Review
Orthopedics
Tianshun Xie, Reinoud W. Brouwer, Inge van den Akker-Scheek, Hugo C. van der Veen
Summary: This study aimed to review the literature on the association between knee joint line obliquity (KJLO) and clinical outcome after high tibial osteotomy (HTO) for medial knee osteoarthritis and summarize the KJLO cut-off value used in these studies. The results showed conflicting findings on the associations between postoperative KJLO and patient-reported outcome, medial knee cartilage regeneration, and 10-year surgical survival. The clinical relevance of KJLO after HTO remains controversial.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Medicine, Research & Experimental
Marlinde L. van Dijk, Leonie M. te Loo, Joyce Vrijsen, Inge van den Akker-scheek, Sanne Westerveld, Marjan Annema, Andre van Beek, Jip van den Berg, Alexander L. Boerboom, Adrie Bouma, Martine de Bruijne, Jeroen Crasborn, Johanna M. van Dongen, Anouk Driessen, Karin Eijkelenkamp, Nies Goelema, Jasmijn Holla, Johan de Jong, Anoek de Joode, Arthur Kievit, Josine van't Klooster, Hinke Kruizenga, Marike van der Leeden, Lilian Linders, Jenny Marks-Vieveen, Douwe Johannes Mulder, Femmy Muller, Femke van Nassau, Joske Nauta, Suzanne Oostvogels, Jessica Oude Sogtoen, Hidde P. van der Ploeg, Patrick Rijnbeek, Linda Schouten, Rhoda Schuling, Erik H. Serne, Simone Smuling, Maarten R. Soeters, Evert A. L. M. Verhagen, Johannes Zwerver, Rienk Dekker, Willem van Mechelen, Judith G. M. Jelsma
Summary: This study aims to assess the effectiveness and cost-effectiveness of a dedicated lifestyle front office (LFO) in promoting patient-centered lifestyle care and connecting with community-based lifestyle initiatives. Two parallel pragmatic randomized controlled trials will be conducted for cardiovascular disorders and musculoskeletal disorders.
Article
Orthopedics
Mark Zee, Michele Keizer, Jos van Raaij, Juha Hijmans, Inge van den Akker-scheek, Ron Diercks
Summary: The study aimed to determine whether the range of tibial rotation (rTR) increases after ACL injury and whether it returns to normal after ACL reconstruction (ACLR). The results showed that rTR increased during high-demand tasks compared to low-demand tasks. Before ACLR, rTR was smaller in the ACL-deficient knees compared to the contralateral knees. After ACLR, rTR increased compared to pre-operative but was still smaller than the contralateral knees.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Orthopedics
Romy Deviandri, Hugo C. van der Veen, Andri M. T. Lubis, Maarten J. Postma, Inge van den Akker-Scheek
Summary: This study aimed to translate the ACL-RSI scale into Indonesian and evaluate its validity and reliability in Indonesian-speaking patients after ACL reconstruction. After a forward-and-backward translation procedure, the I-ACL-RSI was found to have good construct validity and test-retest reliability in Indonesian patients.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2023)
Article
Orthopedics
Tianshun Xie, Hugo C. van der Veen, Inge van den Akker-Scheek, Reinoud W. Brouwer
Summary: This study investigated the influence of radiographic techniques and osteoarthritis grade on measurements of knee joint line obliquity (KJLO) and KJLO-related frontal deformity. It was found that measurements of JLOAF, JLOAM, JLOAT, MJLA, JLCA, and HKA were influenced by single-leg/double-leg standing, while JLOAF, JLOAM, and JLOAT were also affected by bipedal distance in double-leg standing, and JLCA was affected by osteoarthritis grade. MPTA measurement of knee joint obliquity was not affected by standing position, bipedal distance, or osteoarthritis grade, and had excellent reliability. Thus, MPTA is proposed as the preferable KJLO measurement method for clinical practice and future research.
JOURNAL OF ORTHOPAEDICS
(2023)
Article
Health Care Sciences & Services
Sjoukje Bouma, Martin Stevens, Lucas van der Woude, Ron Diercks, Inge van den Akker-scheek
Summary: This study aimed to identify barriers and facilitators perceived by primary and secondary healthcare professionals in implementing lifestyle-related treatment modalities in patients with hip/knee osteoarthritis. The findings suggest that focusing on societal factors rather than individual factors could improve the implementation of these treatment modalities.
Article
Orthopedics
Tianshun Xie, Maarten R. Huizinga, Inge van den Akker-Scheek, Hugo C. van der Veen, Reinoud W. Brouwer
Summary: This study aimed to analyze the association between change in knee joint line obliquity (KJLO) and patient-reported outcome, radiological progression of osteoarthritis, and surgical survival after lateral closing-wedge high tibial osteotomy (HTO). The results showed that increased KJLO (postoperative MPTA ≥ 95.0°) or MPTA change ≥ 8.0° after HTO did not adversely affect patient-reported outcome, radiological progression of osteoarthritis, or surgical survival at an average 5-year follow-up.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Orthopedics
Romy Deviandri, Hugo C. van der Veen, Andri M. T. Lubis, Maarten J. Postma, Inge van den Akker-Scheek
Summary: The purpose of this study was to determine the responsiveness of ACL-RSI, IKDC, and Lysholm scores in an Indonesian-speaking population with ACL injury. The results showed that all three scores had good responsiveness and can be used for follow-up of patients after ACL injury. At the individual level, IKDC was found to be more efficient than ACL-RSI or Lysholm scores in detecting clinically important changes over time after ACL treatment.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2023)
Article
Rheumatology
Sjoukje Bouma, Inge van den Akker-scheek, Dieuwke Schiphof, Lucas van der Woude, Ron Diercks, Martin Stevens
Summary: This study aims to identify and address barriers to implementing lifestyle-related treatment modalities (LRTMs) in the conservative treatment of patients with hip and/or knee osteoarthritis from the perspective of healthcare professionals (HCPs). Fourteen implementation strategies were selected, including "build a coalition" and "develop stakeholder interrelationships".
MUSCULOSKELETAL CARE
(2023)
Article
Clinical Neurology
Marleen Ieke Tibben, Erik Van Wensen, Beorn Nijenhuis, Johannes Zwerver
Summary: This study presents a case series of 4 advanced skill-level athletes with suspected task-specific dystonia. The combination of standardized behavioural therapy and relaxation techniques, in the form of hypnosis, proved to be a safe and promising treatment, resulting in improvement and full recovery of the athletes' performance.
TREMOR AND OTHER HYPERKINETIC MOVEMENTS
(2023)
