Article
Multidisciplinary Sciences
Lionel D. Fiske, Maurice C. G. Aalders, Mitra Almasian, Ton G. van Leeuwen, Aggelos K. Katsaggelos, Oliver Cossairt, Dirk J. Faber
Summary: Optical coherence tomography (OCT) is an optical technique for volumetric visualization of translucent materials, with additional information gained through depth-resolved attenuation analysis. Despite the presence of speckle causing fluctuations in OCT images, depth-resolved attenuation analysis can still provide insight into tissue structure and organization.
SCIENTIFIC REPORTS
(2021)
Article
Optics
Zhenhe Ma, Ning Ding, Zhen Li, Keliang Zhu, Ang Li, Zhanhong Lin, Yi Wang, Yuqian Zhao, Yao Yu, Jingmin Luan, Xin Zhu, Jian Liu
Summary: This article introduces a method to extract the photoacoustic (PA) signal from the contrast reduction in the interference spectrum obtained from spectral domain optical coherence tomography (SDOCT). The method utilizes the specular reflection on the water surface to achieve all-optical detection in a non-contact manner. By analyzing the phase changes in the interference spectrum induced by water surface vibration, the method enables quantification of the interference contrast reduction for PA imaging.
Article
Optics
Yuye Ling, Zhenxing Dong, Xueshen Li, Yu Gan, Yikai Su
Summary: With the advancement of light source technology, the A-line imaging rate of SS-OCT has significantly increased in the past three decades. However, the bandwidths of data acquisition, transfer, and storage have become major limitations in modern SS-OCT system design. To address this, a novel design paradigm is proposed where the sub-sampling pattern for interferogram acquisition is jointly optimized with the reconstruction algorithm. This method achieves high data compression ratios without impairing image quality, making it a potential solution for the data issue in SS-OCT.
Article
Optics
Tanbin Shao, Kecheng Yang, Min Xia, Wenping Guo
Summary: In this study, an enhanced dispersion-encoded full-range spectral interferometry technique is proposed and validated for improving measurement accuracy in samples with significant depth, inclination, and roughness. By removing the direct current and preserving data with good phase continuity, the accuracy of phase compensation is improved. The proposed technique extends the depth measurement range and achieves high axial measurement precision.
Article
Medicine, General & Internal
Lisa Toto, Maria Ludovica Ruggeri, Federica Evangelista, Chiara Trivigno, Rossella D'Aloisio, Chiara De Nicola, Pasquale Viggiano, Emanuele Doronzo, Marta Di Nicola, Annamaria Porreca, Rodolfo Mastropasqua
Summary: This study investigates the parameters of optical coherence tomography (OCT) and OCT angiography (OCTA) in patients with neovascular age-related macular degeneration (nAMD) and macular neovascularization (MNV) types 1, 2, and 3. The results showed significant differences in CVI, CMT, and ORCCFA between MNV 1 and the other two groups. CVI was significantly different between MNV 1 and healthy controls and between MNV 1 and MNV 2. ORCCFA and CMT were significantly different between MNV 1 and MNV 2. There was no statistically significant difference in subfoveal choroidal thickness (SFCT) among the three groups.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Optics
Zoya Alam, Raju Poddar
Summary: Zebrafish, as a vertebrate model, is widely used in various fields. This study demonstrates the use of optical coherence tomography and optical coherence tomography angiography to image the developing zebrafish, allowing for detailed visualization of microstructures and microvasculature.
OPTICS AND LASERS IN ENGINEERING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Chen Huang, Keren Xie, Yuhan Zhang, Mingchao Li, Songtao Yuan, Qiang Chen
Summary: The proposed fusion method combining SD-OCT and OCTA images is more effective for CNV visualization, providing a satisfying visual effect by integrating complementary information from multimodal images.
Article
Biochemical Research Methods
Vikram Barauah, Shyon Parsa, Naail Chowdhury, Thomas Milner, Henry Grady Rylander III
Summary: This study investigates the detection of morphological changes in Bacillus subtilis using scattering angle resolved optical coherence tomography (SAR-OCT). The results show significant differences in the distribution of backscattering angle during the rod-to-coccus shape transition of the bacteria. The study supports the potential of utilizing SAR-OCT to detect bacterial morphological changes.
JOURNAL OF BIOMEDICAL OPTICS
(2022)
Article
Engineering, Electrical & Electronic
Prabhav Gaur, Andrew Grieco, Yeshaiahu Fainman
Summary: This article presents a method to improve the performance of spectral domain optical coherence tomography by using phase modulators and delay lines as filters, scanning multiple channels and combining them in a digital computer.
IEEE PHOTONICS JOURNAL
(2023)
Article
Chemistry, Analytical
Hong-Yan Zheng, Bo-Liang Chen, Hsiao-Yen Lu, Shih-Hsiang Hsu, Masanori Takabayashi
Summary: A chip-based SD-OCT system utilizes a MZDC structure and an echelle grating for improving signal-to-noise ratios, wavelength response, axial resolution, and sensitivity.
Article
Multidisciplinary Sciences
Margaux Schmeltz, Laurianne Robinet, Sylvie Heu-Thao, Jean-Marc Sintes, Claire Teulon, Guillaume Ducourthial, Pierre Mahou, Marie-Claire Schanne-Klein, Gael Latour
Summary: Advanced nonlinear optical microscopy enables quantitative mapping of parchment degradation at the micrometer scale, using two sensitive parameters to distinguish different degradation stages. Validation of this approach on contemporary and historical parchments demonstrates its effectiveness in assessing conservation state and optimizing restoration methods. NLO quantitative microscopy can help identify at-risk parchments and improve restoration processes.
Article
Ophthalmology
Haidong Li, Lifeng Chen, Meng'ai Wu, Bin Zheng
Summary: This study investigated the characteristics of cystic retinal tufts (CRTs) using widefield spectral-domain optical coherence tomography. The results showed that CRTs exhibited hyperreflective irregular elevated lesions with internal hyporeflective cystoid cavities on SD-OCT images. Widefield SD-OCT imaging provides detailed anatomical information and may guide clinical treatment.
Article
Medicine, General & Internal
Kyu Jin Han, Hyeong Ju Kim, Je Moon Woo, Jung Kee Min
Summary: Retinal layer thickness and capillary vessel density were investigated in patients with spontaneously resolved CSC, showing a decrease in outer retinal layer thickness and choriocapillaris VD. Outer retinal layer thickness may be an important visual predictor of CSC.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Biochemical Research Methods
Tobiloba Adejumo, Tae-Hoon Kim, David Le, Taeyoon Son, Guangying Ma, Xincheng Yao
Summary: This study characterizes the reflectance profiles of retinal blood vessels in optical coherence tomography (OCT) and explores the potential of using these features to guide artery-vein classification in OCT angiography (OCTA) of the human retina. The study reveals unique reflectance features of retinal arteries and veins, and demonstrates that the venous lumen intensity is dependent on vessel size.
BIOMEDICAL OPTICS EXPRESS
(2022)
Article
Biochemical Research Methods
Conrad W. Merkle, Marco Augustin, Danielle J. Harper, Johanna Gesperger, Antonia Lichtenegger, Pablo Eugui, Gerhard Garhofer, Martin Glosmann, Bernhard Baumann
Summary: The study introduces a new method called ExCEL-OCT, which can identify the diffusion of tracer particles around leaky vasculature following injection of a contrast agent, achieving high-resolution 3D vascular leakage measurements for the first time in vivo.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Orthopedics
Paul Cernohorsky, Simon D. Strackee, Geert J. Streekstra, Eroen P. van den Wijngaard, Jos A. E. Spaan, Maria Siebes, Ton G. van Leeuwen, Daniel M. de Bruin
Summary: This study utilized CT-mediated catheter-based optical coherence tomography to digitally reconstruct the articular surface of the TMC joint and assess cartilage thickness in comparison to cryomicrotome data. The results showed a near-perfect agreement between OCT and cryomicrotome thickness measurements. This approach enables accurate cartilage thickness measurements and encourages the development of intraarticular cartilage OCT for future clinical application.
Article
Biochemical Research Methods
Leonie de Rond, Edwin van der Pol, Paul R. Bloemen, Tina Van Den Broeck, Ludo Monheim, Rienk Nieuwland, Ton G. van Leeuwen, Frank A. W. Coumans
Article
Biochemical Research Methods
Anouk L. Post, Henricus J. C. M. Sterenborg, Fransien G. Woltjer, Ton G. van Leeuwen, Dirk J. Faber
JOURNAL OF BIOMEDICAL OPTICS
(2020)
Review
Biochemical Research Methods
Abel Swaan, Berrend G. Muller, Leah S. Wilk, Mitra Almasian, Evita C. H. Zwartkruis, L. Rence Rozendaal, Daniel M. de Bruin, Dirk J. Faber, Ton G. van Leeuwen, Marcel B. van Herk
JOURNAL OF BIOPHOTONICS
(2020)
Article
Nanoscience & Nanotechnology
Agustin Enciso-Martinez, Edwin van der Pol, Aufried T. M. Lenferink, Leon W. M. M. Terstappen, Ton G. van Leeuwen, Cees Otto
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2020)
Article
Optics
Dirk J. Faber, Anouk L. Post, Henricus J. C. M. Sterenborg, Ton G. Van Leeuwen
Article
Cell Biology
Agustin Enciso-Martinez, Edwin Van der Pol, Chi M. Hau, Rienk Nieuwland, Ton G. Van Leeuwen, Leon W. M. M. Terstappen, Cees Otto
JOURNAL OF EXTRACELLULAR VESICLES
(2020)
Review
Biochemical Research Methods
Peijun Gong, Mitra Almasian, Gijs van Soest, Daniel de Bruin, Ton van Leeuwen, David Sampson, Dirk Faber
JOURNAL OF BIOMEDICAL OPTICS
(2020)
Article
Chemistry, Multidisciplinary
Maxime D. Slooter, Sanne M. A. Jansen, Paul R. Bloemen, Richard M. van den Elzen, Leah S. Wilk, Ton G. van Leeuwen, Mark I. van Berge Henegouwen, Daniel M. de Bruin, Suzanne S. Gisbertz
APPLIED SCIENCES-BASEL
(2020)
Article
Cell Biology
Naomi C. Buntsma, Aleksandra Gasecka, Yvo B. W. E. M. Roos, Ton G. van Leeuwen, Edwin van der Pol, Rienk Nieuwland
Summary: In this study, we found that EDTA improves the stability of plasma EVs and is more effective at inhibiting the release of platelet EVs compared to citrate when platelets are activated.
Article
Biology
Sanne M. Jansen, Daniel M. de Bruin, Leah S. Wilk, Mark I. van Berge Henegouwen, Simon D. Strackee, Suzanne S. Gisbertz, Ed T. van Bavel, Ton G. van Leeuwen
Summary: This study investigates the use of fluorescence imaging to evaluate perfusion in the gastric tube during surgery and its correlation with patient outcomes in terms of anastomotic leakage. The study found that poor fundus perfusion is a major factor for the development of anastomotic leakage. Parameters for the quantification of fluorescence signal were tested and compared with patient outcomes. The study concludes that quantitative perfusion imaging can provide early risk stratification of necrosis.
Article
Hematology
Naomi C. Buntsma, Mona Shahsavari, Aleksandra Gasecka, Rienk Nieuwland, Ton G. van Leeuwen, Edwin van der Pol
Summary: A practical procedure was developed to determine the optimal sample dilution for plasma in order to prevent swarm detection and maintain significant particle counts in clinical research studies. The optimal dilution factor was found to be ≤1.1×10^2-fold, and the count rate should be <1.1×10^4 events center dot s^(-1).
RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS
(2023)
Article
Optics
Xu U. Zhang, Dirk J. Faber, Ton G. Van Leeuwen, Henricus J. C. M. Sterenborg
JOURNAL OF PHYSICS-PHOTONICS
(2020)
Article
Urology & Nephrology
Esmee I. M. L. Liem, Jan Erik Freund, Cemile Dilara Savci-Heijink, Jean J. M. C. H. de la Rosette, Guido M. Kamphuis, Joyce Baard, Joseph C. Liao, Ton G. van Leeuwen, Theo M. de Reijke, Daniel Martijn de Bruin
EUROPEAN UROLOGY FOCUS
(2020)
Proceedings Paper
Engineering, Biomedical
Dirk J. Faber, Anouk L. Post, Ton G. van Leeuwen
DIFFUSE OPTICAL SPECTROSCOPY AND IMAGING VII
(2019)
