Article
Chemistry, Multidisciplinary
Kristina Kovalcikova Duracikova, Ivan Cimrak
Summary: This study proposes a new method of inertial focusing of cells in microfluidic devices and identifies key parameters that influence cell sorting results through computational simulations.
APPLIED SCIENCES-BASEL
(2022)
Article
Thermodynamics
Karthikeyan Paramanandam, S. Venkatachalapathy, Balamurugan Srinivasan
Summary: This paper studies the flow and heat transfer characteristics of microchannel heatsinks with ribs, cavities and secondary channels using numerical simulations. The impacts of rib width on heat transfer enhancement and the combined effects of secondary channels, ribs, and cavities on lowering the temperature and enhancing heat transfer rate are analyzed. The research provides insights on the design and performance evaluation of microchannel heatsinks for practical applications.
INTERNATIONAL JOURNAL OF NUMERICAL METHODS FOR HEAT & FLUID FLOW
(2022)
Article
Energy & Fuels
Abay Molla Kassa, Sarah E. Gasda, Kundan Kumar, Florin A. Radu
Summary: This study incorporates time-dependent wettability change into the relative permeability-saturation relation through modifying the existing relative permeability function, showing the importance of accurately predicting relative permeability in a dynamically altering porous medium.
JOURNAL OF PETROLEUM SCIENCE AND ENGINEERING
(2021)
Article
Mechanics
Di Li, Le Song, Cheng Zhang, Liandong Yu, Xiangchun Xuan
Summary: The study developed a depth-averaged inertial flow model for Newtonian fluids in shallow microchannels, which was assessed for its validity and accuracy through comparisons with experimental measurements and three-dimensional numerical simulations. The proposed depth-averaged model provides similar accuracy to three-dimensional modeling when the channel depth-to-width ratio is small.
Article
Engineering, Chemical
Jing Li, Xiaobin Liu
Summary: Droplet formation in microchannels with different walls was investigated through simulations based on a pseudopotential model. The surface tension was determined using Laplace's law, and the contact angle was estimated using a linear equation. The effects of surface wettability and the Bond number on droplet motion were studied, and the formation of droplets in a T-junction device was also simulated, analyzing the influence of the capillary number and viscosity ratio on droplet formation.
Article
Construction & Building Technology
Z. R. Shu, Q. S. Li
Summary: This study investigates the characteristics of wind pressure dynamics underneath the separated shear layer using nonlinear dynamic analysis techniques. The results show that the dynamic behavior of wind pressure is closely related to leading edge shape, turbulence intensity, and turbulence scale. As the measurement position moves from leading edge towards downstream, the underlying dynamics of wind pressure become less deterministic. However, once the descriptive indicator reaches its minimum, this pattern is reversed. The minimum value and the position of reversal in the distribution pattern of the dynamic descriptive factor are correlated with the leading edge shape.
ADVANCES IN STRUCTURAL ENGINEERING
(2022)
Article
Mechanics
Yifei Guan, Tianhang Yang, Jian Wu
Summary: The study investigates electrokinetic flow in a microchannel driven by charged surface heterogeneity in the presence of an external electric field through three-dimensional simulations. It is found that the magnitude of the external electric field affects the mixing and transport enhancement of passive scalars by induced electrokinetic vortices.
Article
Thermodynamics
Yee-Ting Lee
Summary: This study investigates the thermal-fluid behaviors of subcooled flow boiling in microchannels through computational and experimental approaches. A computational fluid dynamics (CFD) model is used to simulate the interfacial movements between liquid water and vapor, while experiments are conducted to measure heat transfer and pressure drop outcomes. The results show that a microchannel design with an aspect ratio of 5.0 achieves satisfactory overall thermal and frictional outcomes.
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
(2023)
Article
Engineering, Chemical
Richie Garg, Soham Mujumdar, Amit Agrawal
Summary: This study compares flow friction and pumping power for rarefied gas flows in textured microchannels at different Reynolds numbers. The height of texture is found to be the most important control factor for efficiency, with shape being the least important factor. Knudsen number and TMAC are identified as significant factors for different Reynolds numbers. The research can be applied to design micropiping systems with lower pumping power, lower frictional resistance, and higher efficiency.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2021)
Article
Mechanics
Maryam Maghazeh, Hossein Pishbin, Mahdi Navidbakhsh, Esmail Pishbin
Summary: This study presents a novel approach for generating stratified flow and slug flow for biochemical applications using centrifugal microfluidics. The technique involves stratifying liquid using centrifugal force and trapping bubbles between liquid plugs to form a slug flow. The fluidic behavior of the system is comprehensively characterized using a multiphase numerical model, and the results show that slug flow can significantly enhance the mixing efficiency compared to single-phase or stratified flow.
Article
Engineering, Mechanical
Golchehreh Shajari, Morteza Abbasi, Mehran Khaki Jamei
Summary: This paper presents a numerical investigation of purely oscillatory laminar flows in parallel plate microchannels, studying the development of entrance length under low Reynolds numbers and dimensionless oscillation frequencies. Results indicate that different prediction methods for entrance length are necessary based on varying oscillation frequencies.
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART C-JOURNAL OF MECHANICAL ENGINEERING SCIENCE
(2021)
Article
Thermodynamics
Feng Han, Xiaowei Wang, Fan Zhao, Shiwei Zhang, Zhijun Zhang
Summary: This study investigates the factors affecting gas separation efficiency in microchannels through numerical simulation and controlled variable method. Results show that gas separation efficiency is influenced by temperature difference and surface accommodation coefficient, and the gas accumulation position can be controlled by adjusting the microchannel width, length, and ratchet angle.
INTERNATIONAL JOURNAL OF THERMAL SCIENCES
(2022)
Article
Environmental Sciences
Mingzhe Zhang, Aiguo Xing, Kunzhong Li, Yu Zhuang, Wenbin Chang, Yiwei Liu
Summary: Over the past 20 years, Lebai gully in Tibet, China has experienced multiple debris flow events that have caused blockage in the river channel and posed a threat to cultivated land and properties in the upper reaches of the Yarlung Tsangpo River. However, limited investigations have been conducted on these debris flows, and the triggering mechanism remains unclear. This study provides a detailed demonstration of the geological and geomorphological features of the Lebai Basin, presents the geohazard history of the Lebai gully, and evaluates the subsurface characteristics of debris flow fans using electrical resistivity tomography. The findings suggest that factors such as rainfall, temperature, and earthquakes are closely related to the occurrence of debris flows in Lebai gully.
ENVIRONMENTAL EARTH SCIENCES
(2023)
Article
Mechanics
Leonid Pekker
Summary: This article presents a novel one-dimensional model of microfluidic laminar flows, taking into account inertance and dynamic pressure terms, which can be applied to various flow regimes. The study demonstrates the possibility of liquid meniscus arrest in asymmetric Y-shape junctions through experimental validation.
Article
Engineering, Mechanical
Grant Keady
Summary: This study applies a simple approximation to calculate the volume flow rate in a channel with an elliptic cross section, avoiding the repeated solving of the partial differential equation for different values of the slip parameter.
JOURNAL OF FLUIDS ENGINEERING-TRANSACTIONS OF THE ASME
(2021)
Article
Physiology
Joaquin Flores Geronimo, Eugenia Corvera Poire, Philip Chowienczyk, Jordi Alastruey
Summary: Central blood pressure (cBP) is considered a better marker of cardiovascular disease risk compared to peripheral blood pressure (pBP) based on studies. A methodology for estimating central pulse pressure (cPP) from non-invasive measurements has been developed in this study, showing promising results for improving cardiovascular function assessment.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Physics, Fluids & Plasmas
Pamela Vazquez-Vergara, Ulises Torres-Herrera, Luis F. Olguin, Eugenia Corvera Poire
Summary: Pulsatile pressure gradients are commonly found in microfluidic multiphase systems where fluid movement is affected by fluid-fluid interfaces. A simple theoretical model incorporating dynamic interfacial curvatures was presented, showing a resonant behavior for dynamic permeability. Experimental validation of the model highlighted the impact of interfaces on flow velocity at low frequencies.
PHYSICAL REVIEW FLUIDS
(2021)
Article
Mechanics
Ulises Torres-Herrera, Eugenia Corvera Poire
Summary: By analytically deriving equations of motion, we have identified the dynamic characteristics of fluids confined within elastic nanotubes subjected to periodic bending deflections, and conclusions for two limiting situations. These results open up possibilities for controlling flow at the nanoscale through tube vibrations.
JOURNAL OF FLUID MECHANICS
(2021)
Article
Biochemistry & Molecular Biology
Claudia Trejo-Soto, Guillermo R. Lazaro, Ignacio Pagonabarraga, Aurora Hernandez-Machado
Summary: This article provides insights into the general features of red blood cell membranes and their impact on blood flow and rheology. It covers the basic description of membranes and focuses on the characteristics and modeling of red blood cell membranes. It also reviews recent studies on the effect of the elastic properties of red blood cell membranes on blood flow and hemorheology, as well as specific hemorheological pathologies associated with the mechanical properties of red blood cells and their influence on microcirculation. The article concludes by discussing the potential of microfluidic applications for diagnosing and treating these diseases, thereby highlighting the importance of studying red blood cell membranes and their role in blood flow.
Article
Mechanics
Elfego Ruiz-Gutierrez, Steven Armstrong, Simon Leveque, Celestin Michel, Ignacio Pagonabarraga, Gary G. Wells, Aurora Hernandez-Machado, Rodrigo Ledesma-Aguilar
Summary: In this study, we investigate the duration of the cross-over between the initial linear growth and the diffusive-like growth in spontaneous capillary imbibition. We find that local-resistance sources, such as inertial resistance and friction caused by the advancing meniscus, always limit the motion of the imbibing front. Our results show that this cross-over is much longer than previously thought, even longer than the time it takes for the liquid to fill the porous medium. This slowly slowing-down dynamics is likely to cause similar long cross-over phenomena in processes governed by wetting.
JOURNAL OF FLUID MECHANICS
(2022)
Article
Physics, Condensed Matter
Pablo Alberto de la Guerra, E. Corvera Poire
Summary: This study investigates the dynamics of a binary fluid, studying the parallel flow of two fluids in a cylindrical geometry driven by pulsatile pressure gradients. The research finds a correlation between the movement of mucus and the frequency of coughing, providing a plausible explanation for the cough frequency in healthy individuals.
JOURNAL OF PHYSICS-CONDENSED MATTER
(2022)
Article
Mechanics
J. Flores Geronimo, A. Hernandez-Machado, E. Corvera Poire
Summary: This study investigates the dynamics of microfluidic fronts driven by pulsatile pressures in the presence of hydrophilic wetting patches. A phase-field model that takes inertia into account is used to track the interface position and analyze how the spacing between the patches affects the advancement of the front. The wetting patterns induce a modulating dynamics of the contact line, leading to effective wetting and modulation of the interface velocity.
Article
Chemistry, Analytical
Claudia Trejo-Soto, Aurora Hernandez-Machado
Summary: The rheological properties of blood, including viscosity and shear thinning behavior, are highly influenced by the concentration, membrane elasticity, and aggregation of its red blood cells. This study presents two methods for normalizing the viscosity of blood samples from different donors, based on erythrocyte concentration and shear rate. By introducing a non-dimensional coefficient that considers the response to shear rate, the proposed methodology can predict the health conditions of blood samples. Through these normalization methods, the differences between red blood cells in the samples can be determined, and a range can be defined for describing healthy blood samples with a single behavior.
Article
Mathematics
Angela Jimenez-Casas, Mario Castro, Manuel Villanueva-Pesqueira
Summary: This study investigates the influence of elasticity on the dynamics of chaotic systems by examining various models derived from mechanics, immunology, ecology, and rheology. The findings reveal that elasticity profoundly alters the chaotic dynamics of these systems, highlighting the non-trivial and non-monotonic role of elasticity in controlling or lack of control of chaotic behavior across different scales.
Article
Computer Science, Information Systems
Jaime Perez, Mario Castro, Gregorio Lopez
Summary: The gaming industry plays a crucial role in entertainment, but serious games have also been used for language learning, value conveyance, and skill training. The resurgence of AI and data science provides an opportunity for integrating them into video games. This paper aims to explore the intersection of serious games, AI, and computational social science as novel research tools to understand human behavior and society.
Article
Chemistry, Physical
Andreu F. Gallen, J. Roberto Romero-Arias, Rafael A. Barrio, Aurora Hernandez-Machado
Summary: The process of vesicle formation depends on the membrane geometry. We demonstrate that vesicle formation can be promoted by temperature using a membrane phase field model with Gaussian curvature. We find a phase transition between fluctuating and vesiculation phases that depends on temperature, spontaneous curvature, and the ratio between bending and Gaussian moduli. The main driving force for these processes is the Gaussian energy term, with the curvature energy term also contributing. We also find that the chemical potential can be used to investigate the temperature of the system. Finally, we show that temperature changes the condition for spontaneous vesiculation for all geometries, expanding the range of values for the Gaussian modulus.
Article
Physics, Fluids & Plasmas
Enrique Rodriguez-Fernandez, Silvia N. Santalla, Mario Castro, Rodolfo Cuerno
Summary: The one-dimensional KPZ equation is a paradigm for the scaling of classical and quantum systems with strong correlations. Using numerical simulations, a well-defined universality class is identified for the zero surface tension or zero viscosity case, featuring intrinsically anomalous kinetic roughening and ballistic dynamics. This finding has implications for experiments on quantum spin chains.
Article
Multidisciplinary Sciences
Flavia Feliciangeli, Hanan Dreiwi, Martin Lopez-Garcia, Mario Castro Ponce, Carmen Molina-Paris, Grant Lythe
Summary: By choosing suitable sequences of compartments, the maintenance of product cell populations can be efficient and avoid certain disadvantages.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2022)
Article
Materials Science, Multidisciplinary
Eunsu Lee, J. Seo, J. Munoz-Garcia, M. Castro, R. Cuerno, J-S Kim
Summary: In this study, ordered surface nanostructures are produced on the surface of graphene by irradiation with low-energy ion beams. The transition from small dots to cellular structures is observed at different fluences. The comparison between experimental findings and simulations based on ion-driven viscous flow highlights the importance of considering external noise and the grain structure of the target in fully understanding the large-scale properties of the process.
Article
Chemistry, Physical
Andreu F. Gallen, Mario Castro, Aurora Hernandez-Machado
Summary: Research on the mechanical properties of red blood cells can improve the diagnosis of blood-related diseases. This paper introduces an alternative phase-field model for two-dimensional cells, simplifying numerical implementation and reproducing various cell morphologies. The study integrates red blood cell dynamics in Poiseuille flow and discovers a new metastable shape, providing insights into the dynamical response of blood.