Article
Cardiac & Cardiovascular Systems
Yi Shen, Zheng Shen, Ping Li, Zhangrong Chen, Bo Wei, Danan Liu, Xiaoyun Si, Jiayi Pan, Daiqin Wu, Wei Li
Summary: In this study, the anti-oxidation capacity of Malus doumeri leaf extract (MDLE) was tested. The results showed that MDLE has significant scavenging effects on various radicals and can protect myocardial cells from oxidative damage. The main active components of MDLE were identified as chlorogenic acid, isoquercitrin, quercetin, baicalin, and phloretin.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Food Science & Technology
Shakeela Khalid, Muhammad Arshad, Shahid Mahmood, Waleed Ahmed, Farzana Siddique, Waseem Khalid, Mehwish Zarlasht, Turky Omar Asar, Faten A. M. Hassan
Summary: The study found that Moringa oleifera leaf powder contains rich bioactive compounds, including amino acids, phenols, flavonoids, and saponins. These compounds exhibit higher antioxidant activity, highlighting its strong nutritional worth.
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
(2023)
Article
Multidisciplinary Sciences
Armin Ahmad Nejhad, Behrooz Alizadeh Behbahani, Mohammad Hojjati, Alireza Vasiee, Mohammad Amin Mehrnia
Summary: This study demonstrates that Calotropis procera leaf aqueous extract is rich in phenolic and flavonoid compounds, exhibiting high antioxidant properties. The extract shows high cytotoxicity against HT 29 cells in vitro, with varying resistance against Escherichia coli and Staphylococcus aureus. Morphological changes of these strains were observed through microscopy.
SCIENTIFIC REPORTS
(2023)
Article
Nutrition & Dietetics
Agnieszka Zembron-Lacny, Edyta Wawrzyniak-Gramacka, Anna Ksiazek, Aleksandra Zagrodna, Wieslaw Kopec, Malgorzata Slowinska-Lisowska
Summary: Intense physical exercise leads to increased production of reactive oxygen and nitrogen species. This study examined the effects of dipeptide intake combined with exercise on the oxi-antioxidant response. The results showed that dipeptide intake led to a significant increase in the NO/H2O2 ratio after exercise, indicating enhanced antioxidant status. Additionally, dipeptides were found to reduce C-reactive protein levels, suggesting their anti-inflammatory properties. These findings suggest that dipeptides have potential in reducing oxidative stress and inflammation in physically active individuals.
Article
Plant Sciences
Adarly Kroth, Maria do Carmo Quevedo Santos, Thaisla Cristiane Borella da Silva, Elza Maria Santos Silveira, Wania Aparecida Partata
Summary: The study demonstrated that the aqueous extract from L. divaricata leaves can improve the sciatic functional index and modulate oxidative stress markers in injured sciatic nerve and spinal cord of rats with neuropathic pain. The antinociceptive effect of the extract involves modulation of oxidative stress markers in the injured nerves and spinal cord.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Chemistry, Applied
Zimo Zhang, Yong Peng, Wenbo Meng, Lingdong Pei, Xiaoyan Zhang
Summary: Seabuckthorn leaf extract inhibits browning of fresh-cut potatoes by competitively inhibiting polyphenol oxidase, reducing the activity of peroxidase and phenylalanine ammonia-lyase, decreasing phenolic content, and elevating antioxidant capacity.
Article
Biochemical Research Methods
Xiaoyan Liu, Xiang Liu, Ying Wang, Haidan Sun, Zhengguang Guo, Xiaoyue Tang, Jing Li, Xiaolian Xiao, Shuxin Zheng, Mengxi Yu, Chengyan He, Jiyu Xu, Wei Sun
Summary: Glaucoma is the leading cause of irreversible blindness worldwide. The common proteome features of three types of glaucoma include immune response, lipid metabolism, and cell death. Differential proteomic analysis of PAACG, PCACG, and NVG showed different proteome characterization of the three types of glaucoma.
MOLECULAR & CELLULAR PROTEOMICS
(2021)
Article
Plant Sciences
Juliet Nnenda Olayinka, Raymond Iduojemu Ozolua, Abigail Mebu Akhigbemen
Summary: The aqueous leaf extract of Blighia sapida contains bioactive compounds such as chlorogenic acid, saponins, tannins, and quercetin. It exhibited analgesic properties in mice, specifically inhibiting acetic acid-induced writhing and formalin-induced paw licking pain in the inflammatory phase. The analgesic activity of the extract is mediated by peripheral mechanisms rather than central mechanisms.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Cell Biology
Min Lu, Shen Wang, Tao Wang, Sisi Hu, Brijesh Bhayana, Momoko Ishii, Yifei Kong, Yuchen Cai, Tianhong Dai, Wenguo Cui, Mei X. Wu
Summary: The combination therapy of blue light and phytochemical carvacrol was found to effectively kill a range of bacteria, including antibiotic-resistant strains, with significant efficacy against acute and established infections. This unique phototoxic reaction selectively targeted bacteria without adverse effects on mammalian cells or host DNA, providing a promising strategy to combat multidrug-resistant bacteria.
SCIENCE TRANSLATIONAL MEDICINE
(2021)
Article
Chemistry, Applied
Micheli Negri Brusamarello, Antonio Pedro Brusamarello, Mario Antonio Alves da Cunha, Cleverson Busso
Summary: This study investigated the phenolic compounds, antioxidant and antimicrobial activity, and phytochemical potential of B. trimera leaf extract obtained by decoction. The results showed that the extract was rich in phenolic compounds and had a high capacity for scavenging radicals. High concentrations of chlorogenic, ferulic, caffeic, and cinnamic phenolic acids were found. Additionally, the extract exhibited antimicrobial activity against gram-negative bacteria. These findings suggest that B. trimera leaf extract may be a promising low-cost agent for prophylactic treatment and reducing production costs.
NATURAL PRODUCT RESEARCH
(2023)
Article
Multidisciplinary Sciences
Yared Wasihun, Habtemariam Alekaw Habteweld, Kassahun Dires Ayenew
Summary: This study evaluated the antibacterial activities of crude and fractionated extracts of Calpurnia aurea leaves against different bacterial strains. The extracts showed inhibitory effects on both gram-positive and gram-negative bacteria, similar to the positive control. Fractionation enhanced the antibacterial effect, particularly against Staphylococcus aureus. These findings support the traditional use of C. aurea for treating skin infections.
SCIENTIFIC REPORTS
(2023)
Article
Plant Sciences
Masarat Nabi, Mohammed Iqbal Zargar, Nahida Tabassum, Bashir Ahmad Ganai, Shahid Ud Din Wani, Sultan Alshehri, Prawez Alam, Faiyaz Shakeel
Summary: This study aimed to identify bioactive compounds and evaluate the antibacterial activity of Skimmia anquetilia. The results showed that the methanol leaf extract of S. anquetilia contained 35 distinct phytoconstituents, with the most predominant compound being 2R-acetoxymethyl-1,3,3-trimethyl-4t-(3-methyl-2-buten-1-yl)-1t-cyclohexanol. The extract exhibited significant antibacterial activity against various bacteria, particularly against Escherichia coli, highlighting the potential of S. anquetilia for the development of herbal medicines.
Article
Multidisciplinary Sciences
Wafa'a A. Al-Taisan, Nadiyah M. Alabdallah, Lolwah Almuqadam
Summary: The study found that the use of Moringa leaf extract and green algae significantly improved the development and physiology of Mentha species under salt stress conditions.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Igor V. Rzhepakovsky, David A. Areshidze, Svetlana S. Avanesyan, Wolf D. Grimm, Natalya V. Filatova, Aleksander V. Kalinin, Stanislav G. Kochergin, Maria A. Kozlova, Vladimir P. Kurchenko, Marina N. Sizonenko, Alexei A. Terentiev, Lyudmila D. Timchenko, Maria M. Trigub, Andrey A. Nagdalian, Sergei I. Piskov
Summary: The methanolic extract of leaves of Chlorophytum comosum contains various bioactive constituents, including a compound not previously found in Chlorophytum. The water fraction of the extract exhibits promising antitumor potential.
Article
Agriculture, Dairy & Animal Science
Yanan Cao, Shuoshuo Zhang, Yanjie Huang, Shuai Zhang, Haifei Wang, Wenbin Bao
Summary: In this study, researchers found that an aqueous leaf extract of M. oleifera (MOE) exhibited antiviral activity against PEDV infection by inhibiting viral replication. MOE suppressed oxidative stress and inflammatory cytokine expression induced by PEDV, and upregulated the expression of anti-apoptotic proteins, resulting in reduced cell apoptosis.