Why is chemical synthesis and property optimization easier than expected?

Universal characteristics of chemical synthesis and property optimization

(2011) Katharine W. Moore et al.   Chemical Science

Energy landscapes: some new horizons

(2010) David J Wales   CURRENT OPINION IN STRUCTURAL BIOLOGY

Unified analysis of terminal-time control in classical and quantum systems

(2010) A. Pechen et al.   EPL

Control of quantum phenomena: past, present and future

(2010) Constantin Brif et al.   NEW JOURNAL OF PHYSICS

Directed enzyme evolution: climbing fitness peaks one amino acid at a time

(2009) Cara A Tracewell et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Directed evolution of enzymes: Library screening strategies

(2009) Hans Leemhuis et al.   IUBMB LIFE

Enantioselective α-Arylation of Aldehydes via Organo-SOMO Catalysis. An Ortho-Selective Arylation Reaction Based on an Open-Shell Pathway

(2009) Jay C. Conrad et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocatalytic conversion of CO to acetic acid by Clostridium aceticum—Medium optimization using response surface methodology (RSM)

(2008) Jia Huey Sim et al.   BIOCHEMICAL ENGINEERING JOURNAL

Statistical elicitor optimization studies for the enhancement of azadirachtin production in bioreactor Azadirachta indica cell cultivation

(2008) Gunjan Prakash et al.   BIOCHEMICAL ENGINEERING JOURNAL

Descriptor-free molecular discovery in large libraries by adaptive substituent reordering

(2008) Scott R. McAllister et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies

(2008) Peter A DiMaggio et al.   BMC BIOINFORMATICS

A modeling study by response surface methodology and artificial neural network on culture parameters optimization for thermostable lipase production from a newly isolated thermophilic Geobacillus sp. strain ARM

(2008) Afshin Ebrahimpour et al.   BMC BIOTECHNOLOGY

Addressing the Numbers Problem in Directed Evolution

(2008) Manfred T. Reetz et al.   CHEMBIOCHEM

Greatly reduced amino acid alphabets in directed evolution: making the right choice for saturation mutagenesis at homologous enzyme positions

(2008) Manfred T. Reetz et al.   CHEMICAL COMMUNICATIONS

Investigation of metal alloy catalyst for hydrogen release from sodium borohydride for polymer electrolyte membrane fuel cell application

(2008) J PARK et al.   INTERNATIONAL JOURNAL OF HYDROGEN ENERGY

Directed evolution of transketolase substrate specificity towards an aliphatic aldehyde

(2008) E HIBBERT et al.   JOURNAL OF BIOTECHNOLOGY

Response surface methodology as a tool to study the lipase-catalyzed synthesis of betulinic acid ester

(2008) Yamin Yasin et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Search for New Red Phosphors Using Genetic Algorithm-Assisted Combinatorial Chemistry

(2008) Chandramouli Kulshreshtha et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Control landscapes for observable preparation with open quantum systems

(2008) Rebing Wu et al.   JOURNAL OF MATHEMATICAL PHYSICS

Thermostable Bacillus subtilis Lipases: In Vitro Evolution and Structural Insight

(2008) Shoeb Ahmad et al.   JOURNAL OF MOLECULAR BIOLOGY

Control landscapes for two-level open quantum systems

(2008) Alexander Pechen et al.   Journal of Physics A-Mathematical and Theoretical

Shedding light on the efficacy of laboratory evolution based on iterative saturation mutagenesis

(2008) Manfred T. Reetz et al.   Molecular BioSystems

Grand challenges in basic energy sciences

(2008) Graham R. Fleming et al.   PHYSICS TODAY

Integration of high speed microwave chemistry and a statistical ‘design of experiment’ approach for the synthesis of the mitotic kinesin Eg5 inhibitor monastrol

(2008) Toma N. Glasnov et al.   TETRAHEDRON

Enzyme optimization: moving from blind evolution to statistical exploration of sequence–function space

(2008) Richard J. Fox et al.   TRENDS IN BIOTECHNOLOGY

Screening of a one bead–one compound combinatorial library for β-actin identifies molecules active toward Ramos B-lymphoma cells

(2007) Suzanne Miyamoto et al.   ANALYTICAL BIOCHEMISTRY

New catalytic materials for the high-temperature synthesis of hydrocyanic acid from methane and ammonia by high-throughput approach

(2007) S. Moehmel et al.   APPLIED CATALYSIS A-GENERAL

Combinatorial screening of Eu3+ doped TiO2–Y2O3–Gd2O3 ternary system at soft UV excitation

(2007) Duk Hyun Park et al.   JOURNAL OF ALLOYS AND COMPOUNDS

Study of lipase-catalysed synthesis of ascorbyl benzoate in cyclohexanone using response surface methodology

(2007) Long-Xian Lv et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Combinatorial fabrication and high-throughput characterization of a Ti–Ni–Cu shape memory thin film composition spread

(2007) R. Löbel et al.   MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING