Cell fate regulation in early mammalian development

The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos

(2012) E. W. Kuijk et al.   DEVELOPMENT

The Hippo pathway and apico–basal cell polarity

(2011) Alice Genevet et al.   BIOCHEMICAL JOURNAL

Transcript clearance during the maternal-to-zygotic transition

(2011) Claudia B Walser et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells

(2011) M. Saitou et al.   DEVELOPMENT

Elf5 regulation in the Trophectoderm

(2011) David J. Pearton et al.   DEVELOPMENTAL BIOLOGY

Trophectoderm Lineage Determination in Cattle

(2011) Debra K. Berg et al.   DEVELOPMENTAL CELL

Primitive Endoderm Differentiates via a Three-Step Mechanism Involving Nanog and RTK Signaling

(2011) Stephen Frankenberg et al.   DEVELOPMENTAL CELL

A mouse is not a cow

(2011) Janet Rossant   NATURE

Cell fate in the early mouse embryo: sorting out the influence of developmental history on lineage choice

(2011) Samantha A. Morris   REPRODUCTIVE BIOMEDICINE ONLINE

Response: Cell fate in the early mouse embryo – sorting out the influence of developmental history on lineage choice

(2011) Yojiro Yamanaka   REPRODUCTIVE BIOMEDICINE ONLINE

Simulating the Mammalian Blastocyst - Molecular and Mechanical Interactions Pattern the Embryo

(2011) Pawel Krupinski et al.   PLoS Computational Biology

Cell Polarity Regulator PARD6B Is Essential for Trophectoderm Formation in the Preimplantation Mouse Embryo1

(2010) Vernadeth B. Alarcon   BIOLOGY OF REPRODUCTION

Trophoblast Stem Cells1

(2010) R. Michael Roberts et al.   BIOLOGY OF REPRODUCTION

Initiation of trophectoderm lineage specification in mouse embryos is independent of Cdx2

(2010) G. Wu et al.   DEVELOPMENT

Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2

(2010) A. Ralston et al.   DEVELOPMENT

Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment

(2010) O. Alder et al.   DEVELOPMENT

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst

(2010) Y. Yamanaka et al.   DEVELOPMENT

Maternally and zygotically provided Cdx2 have novel and critical roles for early development of the mouse embryo

(2010) Agnieszka Jedrusik et al.   DEVELOPMENTAL BIOLOGY

Nanog is required for primitive endoderm formation through a non-cell autonomous mechanism

(2010) Daniel M. Messerschmidt et al.   DEVELOPMENTAL BIOLOGY

The primitive endoderm lineage of the mouse blastocyst: Sequential transcription factor activation and regulation of differentiation by Sox17

(2010) Jérôme Artus et al.   DEVELOPMENTAL BIOLOGY

Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst

(2010) Guoji Guo et al.   DEVELOPMENTAL CELL

Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenance

(2010) B. L. Kidder et al.   GENOME RESEARCH

Making the blastocyst: lessons from the mouse

(2010) Katie Cockburn et al.   JOURNAL OF CLINICAL INVESTIGATION

Sox2 Is Essential for Formation of Trophectoderm in the Preimplantation Embryo

(2010) Maria Keramari et al.   PLoS One

Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo

(2010) S. A. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo

(2010) P. J. Rugg-Gunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic regulatory mechanisms during preimplantation development

(2009) Gareth N. Corry et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Nanog Is the Gateway to the Pluripotent Ground State

(2009) Jose Silva et al.   CELL

Cross-regulation of the Nanog and Cdx2 promoters

(2009) Lingyi Chen et al.   CELL RESEARCH

Optimal Timing of Inner Cell Mass Isolation Increases the Efficiency of Human Embryonic Stem Cell Derivation and Allows Generation of Sibling Cell Lines

(2009) Alice E. Chen et al.   Cell Stem Cell

Genetic and epigenetic control of early mouse development

(2009) Mareike Albert et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo

(2009) J. Nichols et al.   DEVELOPMENT

Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse

(2009) J. Rossant et al.   DEVELOPMENT

Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst

(2009) Sigolène M. Meilhac et al.   DEVELOPMENTAL BIOLOGY

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

Porcine pluripotency cell signaling develops from the inner cell mass to the epiblast during early development

(2009) Vanessa J. Hall et al.   DEVELOPMENTAL DYNAMICS

Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells

(2009) P. Yuan et al.   GENES & DEVELOPMENT

GATA3 Is Selectively Expressed in the Trophectoderm of Peri-implantation Embryo and Directly RegulatesCdx2Gene Expression

(2009) Pratik Home et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo

(2009) Magdalena Zernicka-Goetz et al.   NATURE REVIEWS GENETICS

Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal

(2009) Myriam Hemberger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

microRNA Expression during Trophectoderm Specification

(2009) Srinivas R. Viswanathan et al.   PLoS One

Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells

(2009) J. Sheik Mohamed et al.   RNA

Adhesive and Signaling Functions of Cadherins and Catenins in Vertebrate Development

(2009) E. Stepniak et al.   Cold Spring Harbor Perspectives in Biology

ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage

(2009) Leng-Siew Yeap et al.   Epigenetics & Chromatin

NANOG Is a Direct Target of TGFβ/Activin-Mediated SMAD Signaling in Human ESCs

(2008) Ren-He Xu et al.   Cell Stem Cell

Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst

(2008) B. Plusa et al.   DEVELOPMENT

Determination of microRNAs in mouse preimplantation embryos by microarray

(2008) Yanhong Yang et al.   DEVELOPMENTAL DYNAMICS

Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell mass in the mouse embryo

(2008) A. Jedrusik et al.   GENES & DEVELOPMENT

Noncoding RNA in development

(2008) Paulo P. Amaral et al.   MAMMALIAN GENOME

DNA methylation in development and human disease

(2008) Suhasni Gopalakrishnan et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5

(2008) Ray Kit Ng et al.   NATURE CELL BIOLOGY

Ras-MAPK signaling promotes trophectoderm formation from embryonic stem cells and mouse embryos

(2008) Chi-Wei Lu et al.   NATURE GENETICS

Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo

(2007) Amy Ralston et al.   DEVELOPMENTAL BIOLOGY

Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos

(2007) Noriyuki Nishioka et al.   MECHANISMS OF DEVELOPMENT