Effect of particle agglomeration in nanotoxicology

What are the local and systemic biologic reactions and mediators to wear debris, and what host factors determine or modulate the biologic response to wear particles?

(2016) Rocky S. Tuan et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

From implantation to degradation — are poly (l-lactide)/multiwall carbon nanotube composite materials really cytocompatible?

(2014) Magdalena Obarzanek-Fojt et al.   Nanomedicine-Nanotechnology Biology and Medicine

Effect of Treatment Media on the Agglomeration of Titanium Dioxide Nanoparticles: Impact on Genotoxicity, Cellular Interaction, and Cell Cycle

(2013) Raju Y. Prasad et al.   ACS Nano

Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons

(2013) Anna A. Shvedova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Large Uptake of Titania and Iron Oxide Nanoparticles in the Nucleus of Lung Epithelial Cells as Measured by Raman Imaging and Multivariate Classification

(2013) Linnea Ahlinder et al.   BIOPHYSICAL JOURNAL

Agglomeration and sedimentation of titanium dioxide nanoparticles (n-TiO2) in synthetic and real waters

(2013) Andrea Brunelli et al.   JOURNAL OF NANOPARTICLE RESEARCH

Cellular uptake and localization of inhaled gold nanoparticles in lungs of mice with chronic obstructive pulmonary disease

(2013) Marianne Geiser et al.   Particle and Fibre Toxicology

Effects of Particle Size and Surface Modification on Cellular Uptake and Biodistribution of Polymeric Nanoparticles for Drug Delivery

(2013) Sneha A. Kulkarni et al.   PHARMACEUTICAL RESEARCH

Drug Delivery with Topically Applied Nanoparticles: Science Fiction or Reality?

(2013) J. Lademann et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Nanoparticle Accumulation in Angiogenic Tissues: Towards Predictable Pharmacokinetics

(2013) Kristin Yaehne et al.   Small

Size-dependent cellular uptake efficiency, mechanism, and cytotoxicity of silica nanoparticles toward HeLa cells

(2013) Jie Zhu et al.   TALANTA

Presence of Nano-Sized Silica during In Vitro Digestion of Foods Containing Silica as a Food Additive

(2012) Ruud Peters et al.   ACS Nano

The potential of TiO2 nanoparticles as carriers for cadmium uptake in Lumbriculus variegatus and Daphnia magna

(2012) Nanna B. Hartmann et al.   AQUATIC TOXICOLOGY

Biological interactions and toxicity of nanomaterials in the respiratory tract and various approaches of aerosol generation for toxicity testing

(2012) Otto Creutzenberg   ARCHIVES OF TOXICOLOGY

Distinctive Toxicity of TiO2 Rutile/Anatase Mixed Phase Nanoparticles on Caco-2 Cells

(2012) Kirsten Gerloff et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Co-Release of Hexabromocyclododecane (HBCD) and Nano- and Microparticles from Thermal Cutting of Polystyrene Foams

(2012) Haijun Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Combined Factors Influencing the Aggregation and Deposition of nano-TiO2 in the Presence of Humic Acid and Bacteria

(2012) Indranil Chowdhury et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Natural colloids are the dominant factor in the sedimentation of nanoparticles

(2012) Joris T.K. Quik et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Aggregation of stabilized TiO2 nanoparticle suspensions in the presence of inorganic ions

(2012) Yang-Hsin Shih et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Change in agglomeration status and toxicokinetic fate of various nanoparticlesin vivofollowing lung exposure in rats

(2012) Otto Creutzenberg et al.   INHALATION TOXICOLOGY

Impact of agglomeration and different dispersions of titanium dioxide nanoparticles on the human related in vitro cytotoxicity and genotoxicity

(2012) Zuzana Magdolenova et al.   JOURNAL OF ENVIRONMENTAL MONITORING

Tissue and cellular distribution of gold nanoparticles varies based on aggregation/agglomeration status

(2012) Athena M Keene et al.   Nanomedicine

Surfactant protein D (SP-D) alters cellular uptake of particles and nanoparticles

(2012) Michaela Kendall et al.   Nanotoxicology

Cytotoxicity and cellular uptake of tri-block copolymer nanoparticles with different size and surface characteristics

(2012) Sourav Bhattacharjee et al.   Particle and Fibre Toxicology

Health impact and toxicological effects of nanomaterials in the lung

(2012) MICHAELA KENDALL et al.   RESPIROLOGY

Exposure to engineered nanoparticles: Model and measurements for accident situations in laboratories

(2012) Tobias Walser et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Assessing the relevance of in vitro studies in nanotoxicology by examining correlations between in vitro and in vivo data

(2012) Xianglu Han et al.   TOXICOLOGY

Excessive Delivery of Nanostructured Matter to Submersed Cells Caused by Rapid Gravitational Settling

(2011) Klaus Wittmaack   ACS Nano

Commercial Titanium Dioxide Nanoparticles in Both Natural and Synthetic Water: Comprehensive Multidimensional Testing and Prediction of Aggregation Behavior

(2011) Stephanie Ottofuelling et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Changes in agglomeration of fullerenes during ingestion and excretion in Thamnocephalus platyurus

(2011) Manomita Patra et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Particle size-dependent and surface charge-dependent biodistribution of gold nanoparticles after intravenous administration

(2011) Stephanie Hirn et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Exposure assessment of workplaces manufacturing nanosized TiO2and silver

(2011) Ji Hyun Lee et al.   INHALATION TOXICOLOGY

Nanomaterial cell interactions: are currentin vitrotests reliable?

(2011) Cordula Hirsch et al.   Nanomedicine

Uptake of nanoparticles by alveolar macrophages is triggered by surfactant protein A

(2011) Christian A. Ruge et al.   Nanomedicine-Nanotechnology Biology and Medicine

Importance of agglomeration state and exposure conditions for uptake and pro-inflammatory responses to amorphous silica nanoparticles in bronchial epithelial cells

(2011) Maurizio Gualtieri et al.   Nanotoxicology

Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

(2011) Mary-Line Jugan et al.   Nanotoxicology

Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration

(2011) Carsten Schleh et al.   Nanotoxicology

Nanoparticle exposure at nanotechnology workplaces: A review

(2011) Thomas AJ Kuhlbusch et al.   Particle and Fibre Toxicology

Polymorph- and Size-Dependent Uptake and Toxicity of TiO2 Nanoparticles in Living Lung Epithelial Cells

(2011) Per Ola Andersson et al.   Small

The effect of agglomeration state of silver and titanium dioxide nanoparticles on cellular response of HepG2, A549 and THP-1 cells

(2011) Anna Lankoff et al.   TOXICOLOGY LETTERS

The adsorption of biomolecules to multi-walled carbon nanotubes is influenced by both pulmonary surfactant lipids and surface chemistry

(2011) Michael Gasser et al.   JOURNAL OF NANOBIOTECHNOLOGY

The emerging field of nanotoxicology

(2010) Christy L. Haynes   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A Nanoparticle Size Series for In Vivo Fluorescence Imaging

(2010) Zoran Popović et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dispersion of TiO2 Nanoparticle Agglomerates by Pseudomonas aeruginosa

(2010) A. M. Horst et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Effects of titanium dioxide nano-particles on growth and some histological parameters of zebrafish (Danio rerio) after a long-term exposure

(2010) Jinyuan Chen et al.   AQUATIC TOXICOLOGY

Cell–cell signaling in co-cultures of macrophages and fibroblasts

(2010) Dolly J. Holt et al.   BIOMATERIALS

Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles

(2010) Chunbai He et al.   BIOMATERIALS

Diffusion of Particles in the Extracellular Matrix: The Effect of Repulsive Electrostatic Interactions

(2010) Triantafyllos Stylianopoulos et al.   BIOPHYSICAL JOURNAL

Endocytosis unplugged: multiple ways to enter the cell

(2010) Sudha Kumari et al.   CELL RESEARCH

Novel Dose Metric for Apparent Cytotoxicity Effects Generated by in Vitro Cell Exposure to Silica Nanoparticles

(2010) Klaus Wittmaack   CHEMICAL RESEARCH IN TOXICOLOGY

Toxicity of Silver Nanoparticles Increases during Storage Because of Slow Dissolution under Release of Silver Ions

(2010) S. Kittler et al.   CHEMISTRY OF MATERIALS

Assessment of the physico-chemical behavior of titanium dioxide nanoparticles in aquatic environments using multi-dimensional parameter testing

(2010) Frank von der Kammer et al.   ENVIRONMENTAL POLLUTION

Stability and Aggregation of Metal Oxide Nanoparticles in Natural Aqueous Matrices

(2010) Arturo A. Keller et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Bacterial cytotoxicity of the silver nanoparticle related to physicochemical metrics and agglomeration properties

(2010) Eunjoo Bae et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Particle size affects the cellular response in macrophages

(2010) Hua Yue et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Biocompatible Nanoscale Dispersion of Single-Walled Carbon Nanotubes Minimizes in vivo Pulmonary Toxicity

(2010) Gökhan M. Mutlu et al.   NANO LETTERS

A complementary definition of nanomaterial

(2010) Wolfgang G. Kreyling et al.   Nano Today

Cellular recognition and trafficking of amorphous silica nanoparticles by macrophage scavenger receptor A

(2010) Galya A. Orr et al.   Nanotoxicology

Stable nanoparticle aggregates/agglomerates of different sizes and the effect of their size on hemolytic cytotoxicity

(2010) Justin M. Zook et al.   Nanotoxicology

Particle and nanoparticle interactions with fibrinogen: the importance of aggregation in nanotoxicology

(2010) Michaela Kendall et al.   Nanotoxicology

Asbestos, carbon nanotubes and the pleural mesothelium: a review and the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma

(2010) Ken Donaldson et al.   Particle and Fibre Toxicology

Impact of agglomeration state of nano- and submicron sized gold particles on pulmonary inflammation

(2010) Ilse Gosens et al.   Particle and Fibre Toxicology

Deposition and biokinetics of inhaled nanoparticles

(2010) Marianne Geiser et al.   Particle and Fibre Toxicology

ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

(2010) Paul M Hinderliter et al.   Particle and Fibre Toxicology

Quantitative Evaluation of Cellular Uptake and Trafficking of Plain and Polyethylene Glycol-Coated Gold Nanoparticles

(2010) Christina Brandenberger et al.   Small

Cellular responses by stable and uniform ultrafine titanium dioxide particles in culture-medium dispersions when secondary particle size was 100nm or less

(2010) Masanori Horie et al.   TOXICOLOGY IN VITRO

ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells

(2010) Ritesh K. Shukla et al.   TOXICOLOGY IN VITRO

Intracellular distribution, geno- and cytotoxic effects of nanosized titanium dioxide particles in the anatase crystal phase on human nasal mucosa cells

(2010) Stephan Hackenberg et al.   TOXICOLOGY LETTERS

Characterization and grouping of aquatic fulvic acids isolated from clear-water rivers and lakes in Japan

(2010) Kumiko Tsuda et al.   WATER RESEARCH

Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications

(2009) Bengt Fadeel et al.   ADVANCED DRUG DELIVERY REVIEWS

Agglomeration of tungsten carbide nanoparticles in exposure medium does not prevent uptake and toxicity toward a rainbow trout gill cell line

(2009) Dana Kühnel et al.   AQUATIC TOXICOLOGY

Barrier Capacity of Human Placenta for Nanosized Materials

(2009) Peter Wick et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Biological Uptake and Depuration of Carbon Nanotubes by Daphnia magna

(2009) Elijah J. Petersen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Toxicity and Developmental Defects of Different Sizes and Shape Nickel Nanoparticles in Zebrafish

(2009) Cristina Ispas et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs

(2009) Wolfgang G. Kreyling et al.   INHALATION TOXICOLOGY

Relevance of aerosol dynamics and dustiness for personal exposure to manufactured nanoparticles

(2009) Thomas Schneider et al.   JOURNAL OF NANOPARTICLE RESEARCH

Investigation of airborne nanopowder agglomerate stability in an orifice under various differential pressure conditions

(2009) Burkhard Stahlmecke et al.   JOURNAL OF NANOPARTICLE RESEARCH

Agglomeration, isolation and dissolution of commercially manufactured silver nanoparticles in aqueous environments

(2009) Sherrie Elzey et al.   JOURNAL OF NANOPARTICLE RESEARCH

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

What does the cell see?

(2009) Iseult Lynch et al.   Nature Nanotechnology

Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells

(2008) P. V. AshaRani et al.   ACS Nano

Comparative in vivo biocompatibility study of single- and multi-wall carbon nanotubes

(2008) Aneta Fraczek et al.   Acta Biomaterialia

Deposition, Retention, and Translocation of Ultrafine Particles from the Central Airways and Lung Periphery

(2008) Winfried Möller et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ambient nano and ultrafine particles from motor vehicle emissions: Characteristics, ambient processing and implications on human exposure

(2008) L. Morawska et al.   ATMOSPHERIC ENVIRONMENT

3-D Tissue Culture Systems for the Evaluation and Optimization of Nanoparticle-Based Drug Carriers

(2008) Thomas Tyrel Goodman et al.   BIOCONJUGATE CHEMISTRY

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

(2008) Wim H. De Jong et al.   BIOMATERIALS

Agglomeration and sedimentation of TiO2 nanoparticles in cell culture medium

(2008) Zouhir E. Allouni et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Ecotoxicity of engineered nanoparticles to aquatic invertebrates: a brief review and recommendations for future toxicity testing

(2008) A. Baun et al.   ECOTOXICOLOGY

Removal of Oxide Nanoparticles in a Model Wastewater Treatment Plant: Influence of Agglomeration and Surfactants on Clearing Efficiency

(2008) Ludwig K. Limbach et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Interaction of Fullerene (C60) Nanoparticles with Humic Acid and Alginate Coated Silica Surfaces: Measurements, Mechanisms, and Environmental Implications

(2008) Kai Loon Chen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10

(2008) E. Alfaro-Moreno et al.   EUROPEAN RESPIRATORY JOURNAL

Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies

(2008) Jingkun Jiang et al.   JOURNAL OF NANOPARTICLE RESEARCH

Toxicity of amorphous silica nanoparticles in mouse keratinocytes

(2008) Kyung O. Yu et al.   JOURNAL OF NANOPARTICLE RESEARCH

Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats

(2008) Michelle Longmire et al.   Nanomedicine

Role of Particle Size in Phagocytosis of Polymeric Microspheres

(2008) Julie A. Champion et al.   PHARMACEUTICAL RESEARCH

Aggregation and disaggregation of iron oxide nanoparticles: Influence of particle concentration, pH and natural organic matter

(2008) Mohammed Baalousha   SCIENCE OF THE TOTAL ENVIRONMENT

Self-Assembly of Cerium Oxide Nanostructures in Ice Molds

(2008) Ajay S. Karakoti et al.   Small

How Meaningful are the Results of Nanotoxicity Studies in the Absence of Adequate Material Characterization?

(2008) David B. Warheit   TOXICOLOGICAL SCIENCES

DNA damage response to different surface chemistry of silver nanoparticles in mammalian cells

(2008) Maqusood Ahamed et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line

(2008) N.A. Monteiro-Riviere et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effect of particle size of dry powder mannitol on the lung deposition in healthy volunteers

(2007) William Glover et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS