Article
Chemistry, Analytical
Beenish Noureen, Najeeb Ullah, Yulan Tian, Liping Du, Wei Chen, Chunsheng Wu, Ping Wang
Summary: This study developed an electrolyte-insulator semiconductor (EIS) sensor for the label-free detection of saxitoxin (STX), one of the most dangerous shellfish toxins. The sensor was covered with a layer of positively-charged weak polyelectrolyte and utilized a specific aptamer for STX detection. The results showed that the aptasensor had a low detection limit and good selectivity and stability. This sensor provides a convenient approach for the moderate, rapid, and label-free detection of marine biological toxins.
Article
Chemistry, Analytical
Najeeb Ullah, Wei Chen, Beenish Noureen, Yulan Tian, Liping Du, Chunsheng Wu, Jie Ma
Summary: An EIS sensor based on MXene nanosheets was developed for STX detection, achieving high sensitivity and good specificity through aptamer modification, with a low detection limit of 0.03 nM. The method demonstrated good selectivity and stability, showing potential for detecting STX in real samples.
Article
Chemistry, Multidisciplinary
Najeeb Ullah, Beenish Noureen, Yulan Tian, Liping Du, Wei Chen, Chunsheng Wu
Summary: This study presents a label-free EIS sensor for the detection of Saxitoxin (STX), a highly toxic shellfish toxin. The sensor is convenient, desirable, and affordable, and demonstrates high selectivity and stability. It enables rapid and label-free detection of marine toxins.
Article
Materials Science, Multidisciplinary
Tung-Ming Pan, Yu-Shu Huang, Jim-Long Her
Summary: A super-Nernstian pH-sensitive TbTaO4 sensing film was developed for an EIS solid-state pH sensor, showing the best sensing performance when processed with 120 W of tantalum plasma power. The film fabrication process and analysis represent a promising approach for exploring a novel pH-sensitive TbTaO4 film with good selectivity for H+ ions.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Materials Science, Ceramics
Yitao Yang, Kaixin Ge, Pan Tao, Shixun Dai, Xunsi Wang, Wei Zhang, Tiefeng Xu, Yin Wang, Ting-Jung Lin, Peiqing Zhang
Summary: A highly sensitive mid-infrared evanescent wave sensor based on side-polished chalcogenide fiber was proposed in this work. The optimum optical fiber parameters were determined via numerical simulation by detecting the leakage intensity of evanescent waves from the optical fiber of different polish depths. Graphene oxide was coated on the fiber to enhance its sensitivity for butane gas detection, resulting in a three to five times improvement compared to the original fiber optic sensor and SPF sensor, as well as a fast response time and good repeatability.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Multidisciplinary
Zhenhui Yuan, Xiaodan Li, Sannian Song, Zhitang Song, Jiawei Zha, Gang Han, Bingjun Yang, Takehito Jimbo, Koukou Suu
Summary: By doping Si into AsSe, researchers have successfully regulated the threshold voltage and reduced the I-off value, achieving faster operation speed and greater endurance. The Si-AsSe OTS materials exhibit better thermal stability compared to AsSe, paving the way for further OTS material development.
JOURNAL OF MATERIALS CHEMISTRY C
(2021)
Article
Chemistry, Multidisciplinary
Won Hyung Lee, Sun Geun Yoon, Huding Jin, Jeeyoung Yoo, Junghyup Han, Yong Hyun Cho, Youn Sang Kim
Summary: This study discusses the change in electrical properties of electrodes caused by ion adsorption at the solid-liquid interface, and demonstrates a sophisticated Hall measurement system for quantitative analysis of electron density change. An enhanced EIS-structured device is designed to monitor ion dynamics in liquid electrolyte media, confirming ion concentration dependence and specificity.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Analytical
Bahareh Badamchi, Al-Amin Ahmed Simon, Maria Mitkova, Harish Subbaraman
Summary: A novel chalcogenide glass-capped optical fiber temperature sensor is demonstrated, which can operate in harsh environments and respond rapidly to temperature changes. By utilizing the heat-induced phase change property of ChGs, the sensor accurately measures the temperature at the sensing node and interprets the temperature profile in real-time using an array structure. The unique radiation-hardness property of ChGs makes the devices compatible with high-temperature and high-radiation environments.
Article
Electrochemistry
Tung-Ming Pan, Chi-Lin Chan
Summary: This study investigated HfO2 thin films deposited on silicon substrates using different methods for pH sensing applications. Through examination of surface structures and properties, the ALD method was found to have higher pH sensitivity, lower drift rate, and smaller hysteresis voltage compared to the sputtering method. The ALD-HfO2 sensing film on nanoimprinted Si substrate demonstrated a better pH response and is a promising candidate for pH sensing applications in advanced CMOS technology.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2021)
Article
Chemistry, Physical
Kongshik Rho, Eun Bee Sohn, Su Jin Lee, Peter S. Toth, Abbas Vali, Noseung Myung, Csaba Janaky, Krishnan Rajeshwar
Summary: A strategy for preparing CdS/MoS2 heterostructures was described in this study, where CdS/MoS2 particles were formed by derivatizing the excess sulfur intrinsic in the electrodeposited MoS3 surface with Cd through adjustment of medium pH and interfacial electrochemistry. The formation of heterojunction between MoS2 and CdS particles was confirmed, and the nonoptimized CdS/MoS2 heterostructures showed improved photoelectrochemical response for oxidation of sulfite species compared with CdS or MoS2.
ACS APPLIED ENERGY MATERIALS
(2021)
Article
Chemistry, Analytical
Arshak Poghossian, Tobias Karschuck, Patrick Wagner, Michael J. Schoning
Summary: This work presents a theoretical model and experimental study on electrolyte-insulator-semiconductor capacitors (EISCAP) decorated with ligand-stabilized charged gold nanoparticles. The impact of AuNP coverage on C-V curves and ConCap signals was simulated and studied experimentally, and the surface of AuNP-modified EISCAPs was characterized using scanning electron microscopy.
Article
Materials Science, Multidisciplinary
P. Dong, Q. Jiao, Y. Zhang, B. Ma, H. Shan, S. Dai, T. Xu
Summary: A novel GaxGe(4-x)Sb64S128-40AgI glass system was synthesized with different Ge/Ga ratios, showing that the addition of gallium can increase the glass conductivity, with the highest conductivity observed at x=1. These findings provide new insights for the application of metal-doped sulfur solid electrolytes in batteries.
CHALCOGENIDE LETTERS
(2021)
Article
Materials Science, Ceramics
Bing Yuan, Bruce G. Aitken, Derrick C. Kaseman, Ping Yu, Sabyasachi Sen
Summary: The atomic structure of glass along the P4Se3-As4Se3 join with different compositions was studied using various spectroscopic techniques. The results showed the coexistence of cage-like molecular moieties and corner-shared network moieties in these glasses. The increase in substitution of As with P correlated with an increase in the ratio of molecules to network, which also affected the glass transition temperature.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2023)
Article
Optics
Lin Zhang, Allen Y. Yi
Summary: In this study, a novel rapid precision surface molding technique utilizing graphene coating for localized rapid heating was developed. The technique resulted in rapid heating of mold surfaces, improved anti-adhesion, high replication fidelity, and lower energy consumption compared to conventional methods. The graphene-coated silicon wafer showed high thermal response and repeatability, enabling the replication of structures and patterns with high accuracy.
Article
Chemistry, Analytical
Yuefeng Wang, Weiwei Chen, Pengjun Wang, Shixun Dai, Jun Li, Yan Li, Qiang Fu, Tingge Dai, Hui Yu, Jianyi Yang
Summary: A suspended slot chalcogenide glass waveguide gas sensor is proposed, designed, and analyzed in detail, achieving high power confinement factor within a specific wavelength range and demonstrating strong detection performance for methane gas. The optimization of structural parameters leads to improved sensitivity and limit of detection for the proposed waveguide sensor.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Materials Science, Multidisciplinary
Denise Molinnus, Heiko Iken, Anna Lynn Johnen, Benjamin Richstein, Lena Hellmich, Arshak Poghossian, Joachim Knoch, Michael J. Schoening
Summary: Miniaturized electrolyte-insulator-semiconductor capacitors with ultrathin gate insulators were studied for their pH-sensitive sensor characteristics. Different combinations of gate insulator layer structures were characterized and it was found that SiO2-Ta2O5 stack showed the best overall sensor characteristics, while Si3N4-Ta2O5 stack had the highest accumulation capacitance and steepest slope in the capacitance-voltage curve among the studied systems.
PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE
(2022)
Article
Chemistry, Analytical
Melanie Welden, Arshak Poghossian, Farnoosh Vahidpour, Tim Wendlandt, Michael Keusgen, Christina Wege, Michael J. Schoening
Summary: Utilizing tobacco mosaic virus particles as nanoscaffolds, a bi-enzyme EISCAP biosensor was developed for sequential detection of penicillin and urea. The biosensor exhibited high sensitivity and precision, and could also mimic an enzyme logic gate.
Article
Chemistry, Medicinal
Dua Ozsoylu, Torsten Wagner, Michael Josef Schoening
Summary: This review presents the technological advances and challenges of electrochemical cell-based biosensors, with a focus on recent research in the past five years. It covers topics such as cell-based biological field-effect devices, impedimetric sensors, and microelectrode arrays, as well as advancements in single-cell monitoring and integration with microfluidics. The article provides a comprehensive discussion on the future potential of electrochemical cell-based biosensors.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Denise Molinnus, Kevin A. Janus, Anyelina C. Fang, Aleksander Drinic, Stefan Achtsnicht, Marius Koepf, Michael Keusgen, Michael J. Schoening
Summary: This study presents the development of a biocompatible glucose biosensor using a fibroin substrate and a screen-printed carbon electrode. The electrode morphology and glucose sensitivity are analyzed, and the sensor shows great potential for in vivo and epidermal applications.
PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE
(2022)
Article
Instruments & Instrumentation
Dua Oezsoylu, Beyza Karatellik, Michael J. Schoening, Torsten Wagner
Summary: Nowadays, biosensors are widely used in various fields and have become an integral part of our daily lives. To overcome the challenges in commercializing cell-based biosensors, a new method of cryopreserving cell monolayers in a ready-to-use setup has been introduced. Photopolymer-based magnetic composites have been developed to improve this method, allowing for controlled location, mobility, and orientation of the cells.
TM-TECHNISCHES MESSEN
(2022)
Article
Food Science & Technology
Farnoosh Vahidpour, Eric Guthmann, Julio Arreola, Yousef Alghazali, Torsten Wagner, Michael J. Schoening
Summary: In this study, an online multi-sensing platform was developed to evaluate various process parameters of food package sterilization. This platform enabled the validation of critical aseptic parameters. By combining multi-sensing platform with microbiological tests, the most effective sterilization conditions were defined. The novel platform allowed for the online and on-site monitoring of the sterilization process, reducing the use of time-consuming and costly microbiological tests.
Article
Chemistry, Analytical
Arshak Poghossian, Tobias Karschuck, Patrick Wagner, Michael J. Schoning
Summary: This work presents a theoretical model and experimental study on electrolyte-insulator-semiconductor capacitors (EISCAP) decorated with ligand-stabilized charged gold nanoparticles. The impact of AuNP coverage on C-V curves and ConCap signals was simulated and studied experimentally, and the surface of AuNP-modified EISCAPs was characterized using scanning electron microscopy.
Article
Chemistry, Analytical
Farnoosh Vahidpour, Yousef Alghazali, Sevilay Akca, Gregor Hommes, Michael J. Schoening
Summary: This work introduces a novel method for the detection of low concentration H2O2 vapor/aerosol, which is mainly used for sterilizing equipment in the medical industry. The microfabrication technique is used to fabricate interdigitated electrode (IDE) structures, which provide high sensitivity and fast response for the sensors. The sensors can detect H2O2 in a concentration range up to 630 ppm, with no cross-sensitivity, and can work stably in repeated sterilization processes.
Article
Chemistry, Analytical
Melanie Welden, Robin Severins, Arshak Poghossian, Christina Wege, Johannes Bongaerts, Petra Siegert, Michael Keusgen, Michael J. Schoning
Summary: This study presents a novel sensor modified with tobacco mosaic virus (TMV) particles as enzyme nanocarriers for the detection of acetoin and diacetyl in alcoholic beverages. The sensor exhibits high sensitivity and long-term stability, and enables the successive detection of acetoin and diacetyl by tuning the pH value of the measurement solution.
Article
Materials Science, Multidisciplinary
Kevin A. Janus, Stefan Achtsnicht, Laura Tempel, Aleksander Drinic, Alexander Kopp, Michael Keusgen, Michael J. Schoening
Summary: In this study, fibroin, polylactide (PLA), and carbon were investigated as biocompatible and biodegradable materials for amperometric biosensors. The carbon electrodes on fibroin and PLA substrates were modified with a glucose oxidase membrane and then encapsulated with the biocompatible material Ecoflex. Different curing parameters of the carbon electrodes were studied to determine their effect on the biosensor characteristics. The morphology of the electrodes was examined using scanning electron microscopy, and the biosensor performance was measured through amperometric measurements of glucose in a phosphate buffer solution.
PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Tobias Karschuck, Stefan Schmidt, Stefan Achtsnicht, Arshak Poghossian, Patrick Wagner, Michael Josef Schoening
Summary: Compared to single-analyte devices, multiplexed systems for multianalyte detection offer advantages such as reduced assay time and sample volume, low cost, and high throughput. In this study, a multiplexing platform was developed for the automated simultaneous characterization of multiple capacitive field-effect sensors using the capacitive-voltage (C-V) and constant-capacitance (ConCap) mode. The platform consists of a multicell arrangement with a common reference electrode, where the sensors are electrically connected to an impedance analyzer via a base station. The system was tested for pH measurements and the label-free detection of ligand-stabilized, charged gold nanoparticles, showing promising results.
PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE
(2023)
Article
Virology
Tim Wendlandt, Claudia Koch, Beate Britz, Anke Liedek, Nora Schmidt, Stefan Werner, Yuri Gleba, Farnoosh Vahidpour, Melanie Welden, Arshak Poghossian, Michael J. Schoening, Fabian J. Eber, Holger Jeske, Christina Wege
Summary: Immunosorbent turnip vein clearing virus (TVCV) particles displaying the IgG-binding domains of Staphylococcus aureus protein A (PA) were purified from plants. These particles could be loaded with antibodies and used for the immobilization of various substances. The TVCVPA carriers showed increased reusability compared to traditional methods, and the virus could be used for durable TVCVPA-assisted electrochemical biosensing.
Article
Chemistry, Analytical
Paulo V. Morais, Pedro H. Suman, Michael J. Schoening, Jose R. Siqueira Jr, Marcelo O. Orlandi
Summary: This study aims to fabricate a reusable and robust sensing unit on an electrolyte-insulator-semiconductor (EIS) device to detect heavy metal ions such as lead and nickel. The EIS-Sn3O4 sensor shows a higher affinity for Pb2+ ions with a sensitivity of approximately 25.8 mV/decade, suggesting its potential as a feasible capacitive field-effect sensor for heavy metal detection.
Article
Chemistry, Analytical
Morten Bertz, Denise Molinnus, Michael J. Schoening, Takayuki Homma
Summary: Hydrogen peroxide (H2O2) is widely used as a sterilization agent in aseptic food processing and medical applications. Little is known about the detailed mechanism of oxidative spore death by H2O2. This study investigates the chemical and morphological changes of Bacillus atrophaeus spores undergoing oxidative damage, revealing two distinct phases of spore death and the role of reactive oxygen species in the process.
Article
Biotechnology & Applied Microbiology
Dua Oezsoylu, Kevin A. Janus, Stefan Achtsnicht, Torsten Wagner, Michael Keusgen, Michael J. Schoening
Summary: Skin grafting is a common surgical procedure in dermatology, but failure rates are still high, causing significant burden. Real-time and objective monitoring of grafts is essential for evidence-based treatment. Advanced sensor applications using nanotechnology and material science can provide this monitoring.
SENSORS AND ACTUATORS REPORTS
(2023)
