In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells

Human stem cell-derived hepatocytes: breakthrough of an expedient tool for preclinical assessment of drug-induced liver injury?

(2014) Robim M. Rodrigues et al.   ARCHIVES OF TOXICOLOGY

Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease

(2013) Cynthia A. Moylan et al.   HEPATOLOGY

Human Skin-Derived Stem Cells as a Novel Cell Source for In Vitro Hepatotoxicity Screening of Pharmaceuticals

(2013) Robim M. Rodrigues et al.   STEM CELLS AND DEVELOPMENT

The adverse outcome pathway concept: A pragmatic tool in toxicology

(2013) Mathieu Vinken   TOXICOLOGY

Accurate Prediction of Drug-Induced Liver Injury Using Stem Cell-Derived Populations

(2013) Dagmara Szkolnicka et al.   Stem Cells Translational Medicine

The Relevance of Liver Histology to Predicting Clinically Meaningful Outcomes in Nonalcoholic Steatohepatitis

(2012) Mangesh R. Pagadala et al.   Clinics in Liver Disease

Drug-induced Liver Steatosis and Phospholipidosis: Cell-Based Assays for Early Screening of Drug Candidates

(2012) M. Teresa Donato et al.   CURRENT DRUG METABOLISM

The mechanistic basis for the induction of hepatic steatosis by xenobiotics

(2011) David E Amacher   Expert Opinion on Drug Metabolism & Toxicology

Frequency and Outcomes of Liver Transplantation for Nonalcoholic Steatohepatitis in the United States

(2011) Michael R. Charlton et al.   GASTROENTEROLOGY

Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in heparg cells

(2011) Sébastien Anthérieu et al.   HEPATOLOGY

Generating hepatic cell lineages from pluripotent stem cells for drug toxicity screening

(2010) Melissa A. Baxter et al.   Stem Cell Research

Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells

(2009) Hella Wobser et al.   CELL RESEARCH

Cytometric analysis for drug-induced steatosis in HepG2 cells

(2009) M. Teresa Donato et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The Japanese toxicogenomics project: Application of toxicogenomics

(2009) Takeki Uehara et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis

(2008) N. Anderson et al.   PHARMACOLOGICAL REVIEWS

Diagnosis of Nonalcoholic Fatty Liver Disease: Invasive versus Noninvasive

(2008) Anna Wieckowska et al.   SEMINARS IN LIVER DISEASE

In Vitro Differentiation of Embryonic and Adult Stem Cells into Hepatocytes: State of the Art

(2008) Sarah Snykers et al.   STEM CELLS