Article
Chemistry, Multidisciplinary
Giovanna Vermiglio, Antonio Centofanti, Maria Grazia Piancino, Maria Chiara Malandrino, Michele Runci Anastasi, Giacomo Picciolo, Giuseppina Cutroneo
Summary: The study found increased expression of Laminin, Collagen IV, and MMP-9 in the contralateral muscle during unilateral posterior crossbite, with no significant differences in MMP-2 expression. This suggests a hypertrophic response in the contralateral muscle to compensate for the altered function of the ipsilateral muscle in this type of malocclusion.
APPLIED SCIENCES-BASEL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Li Miao, Fei Huang, Ying-Ying Sun, Wei Jiang, Yong-Jin Chen, Min Zhang
Summary: Psychological stress induces pathological changes, oxidative stress, and inflammation in masseter muscles. Curcumin can significantly alleviate these changes, potentially through the HMGB1/TLR4/NF-kappa B pathway, exerting anti-inflammatory and antioxidant effects.
JOURNAL OF ORAL REHABILITATION
(2022)
Article
Chemistry, Multidisciplinary
Florian Kurt Paternoster, Wolfgang Seiberl
Summary: This study compared the agreement in estimated mVO(2) values among five commonly used approaches based on the same set of CW-NIRS data. Significant differences were found between the approaches, with only TSI vs. Hbmean and Hbdiff vs. HHb yielding comparable results. Therefore, the different approaches to estimate mVO(2) cannot be used interchangeably.
APPLIED SCIENCES-BASEL
(2022)
Article
Nutrition & Dietetics
Jerome Salles, Christelle Guillet, Olivier Le Bacquer, Carmen Malnero-Fernandez, Christophe Giraudet, Veronique Patrac, Alexandre Berry, Philippe Denis, Corinne Pouyet, Marine Gueugneau, Yves Boirie, Heidi Jacobs, Stephane Walrand
Summary: Old rats were found to use pea protein with the same efficiency as casein or whey proteins, with similar effects on body composition, tissue weight, skeletal muscle protein synthesis and degradation. This suggests that using plant-based proteins could help older individuals diversify their protein sources and meet nutritional intake recommendations more easily.
Review
Endocrinology & Metabolism
Miguel Perez-Rodriguez, Jesus R. Huertas, Jose M. Villalba, Rafael A. Casuso
Summary: This study conducted a meta-analysis to investigate the effects of calorie restriction and bariatric surgery on human skeletal muscle mitochondria. The results showed that calorie restriction leads to a decrease in maximal mitochondrial state 3 respiration, while bariatric surgery does not affect mitochondrial respiration and content.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2023)
Article
Cell Biology
Mohammad Shamsul Ola
Summary: This study examined ROS generation and antioxidant enzyme activities in diabetic rat retinas under various conditions, highlighting a potential decrease in ROS generation and glucose oxidation rate in the short-term hyperglycemic state. However, an increase in ROS formation was observed in diabetic retinas compared to controls in vivo, indicating non-mitochondrial sources may play a significant role in ROS generation in diabetic retinas.
Article
Biochemistry & Molecular Biology
Mark R. Viggars, Hazel Sutherland, Christopher P. Cardozo, Jonathan C. Jarvis
Summary: Transcriptional assessments of identical nerve-stimulated resistance exercise in mice and rats reveal concordant and discordant gene regulation and pathways related to muscle growth.
Article
Environmental Sciences
Jialu Bao, Yan Zhang, Ran Wen, Linchao Zhang, Xiaodan Wang
Summary: This study investigated the effects of low level MCZ exposure on mouse ovaries. The results showed that MCZ exposure led to damaged ovarian structure and increased apoptosis in mice, which may be achieved by affecting the function of mitochondrial respiratory chain and inducing oxidative stress.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Geriatrics & Gerontology
Francesca M. Alves, Kai Kysenius, Marissa K. Caldow, Justin P. Hardee, Jin D. Chung, Jennifer Trieu, Dominic J. Hare, Peter J. Crouch, Scott Ayton, Ashley Bush, Gordon S. Lynch, Rene Koopman
Summary: Muscle tissues from dystrophic mice showed increased iron levels and dysregulated iron-related proteins associated with the pathology. Muscle iron levels were manipulated by iron chelation and iron-enriched feed, with chelation reducing fibrosis and reactive oxygen species but suppressing certain proteins, while iron supplementation increased specific proteins without altering other aspects of pathology.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Physiology
Christiano Alves, Laurie Goodyear, Patricia Brum
Summary: This study found that factors secreted by LLC cells induce metabolic stress in muscle cells and cause cancer cachexia in mice. However, a selected clonal LLC cell line that failed to induce metabolic stress in muscle cells also promoted weaker catabolism in mice.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Optics
Piotr Rola, Szymon Wlodarczak, Maciej Lesiak, Adrian Doroszko, Adrian Wlodarczak
Summary: This paper presents the current understanding of the mechanisms of action of LLLT on cells and suggests that a better understanding of the molecular processes occurring within the cell after laser irradiation may introduce new clinical applications of LLLT and enhance its safety profile.
Article
Cell Biology
Keitaro Yamanouchi, Yukie Tanaka, Masanari Ikeda, Shizuka Kato, Ryosuke Okino, Hiroki Nishi, Fumihiko Hakuno, Shin-Ichiro Takahashi, James Chambers, Takashi Matsuwaki, Kazuyuki Uchida
Summary: In the DMD rat, the tongue muscle is less advanced in terms of muscular dystrophy compared to the masseter muscle. The masseter muscle in the DMD rats showed progressive dystrophic changes, accompanied by increased transcription of p16 and p19. On the other hand, the tongue muscle in the DMD rats showed macroglossia due to hypertrophy of myofibers.
Article
Environmental Sciences
Lijuan Xiong, Bin Zhou, Jamie L. Young, Kupper Wintergerst, Lu Cai
Summary: Cadmium exposure can induce testicular damage through ferroptosis, possibly due to iron accumulation and decreased expression of Nrf2, HO-1, SOD2, and SLC7A11.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Food Science & Technology
Melisa Lamri, Antonella della Malva, Djamel Djenane, Marzia Albenzio, Mohammed Gagaoua
Summary: Proteomics plays a significant role in meat research, especially in understanding the changes in proteins during post-mortem. In this study, the proteome of goat Semitendinosus muscle was analyzed at different post-mortem times to uncover the dynamic changes. The analysis revealed the involvement of various pathways, such as binding, transport, calcium homeostasis, muscle contraction, and metabolism. The study also highlighted the importance of energy production, mitochondrial metabolism, and ribosomal proteins in determining meat quality.
Article
Cell Biology
Kiara Gaeberlein, Sarah K. Schroeder, Indrajit Nanda, Claus Steinlein, Thomas Haaf, Eva M. Buhl, Patrick Sauvant, Vincent Sapin, Armand Abergel, Ralf Weiskirchen
Summary: The rat hepatic stellate cell line PAV-1, established two decades ago, is a cellular model for studying hepatic retinoic acid metabolism. Despite being able to store retinyl esters and synthesize retinoic acid, this cell line has been overlooked. Genetically characterized established cell lines, like PAV-1, are valuable for biomedical research as working with in vivo models becomes more complicated.
Article
Dentistry, Oral Surgery & Medicine
Rafaela Scariot, Leonardo Brunet, Bernardo Olsson, Marcelo Palinkas, Simone Cecilio Hallak Regalo, Nelson Luis Barbosa Rebellato, Joao Armando Brancher, Carolina Paes Torres, Kranya Victoria Diaz-Serrano, Erika Calvano Kuchler, Joao Cesar Zielak
Summary: Polymorphisms in DRD2, ANKK1, and COMT are associated with bruxism phenotypes, providing evidence for the relationship between these genes and the phenotypes of tooth grinding and clenching in children.
CRANIO-THE JOURNAL OF CRANIOMANDIBULAR & SLEEP PRACTICE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Fernanda Cristina Toloi Rufato, Luiz Gustavo de Sousa, Priscilla Hakime Scalize, Rossano Gimenes, Isabela Hallak Regalo, Adalberto Luiz Rosa, Marcio Mateus Beloti, Fabiola Singaretti de Oliveira, Karina Fittipaldi Bombonato-Prado, Simone Cecilio Hallak Regalo, Selma Siessere
Summary: The utilization of texturized P (VDF-TrFE)/BT, regardless of the association with photobiomodulation therapy, enhanced bone repair in an experimental model of osteoporosis. However, the combination of photobiomodulation therapy with PTFE can increase the expression of bone cell genes.
CLINICAL ORAL INVESTIGATIONS
(2022)
Review
Dentistry, Oral Surgery & Medicine
Maria Helena Dantas Abreu, Anayza Priscila Lourenco da Silva, Renata Veiga Andersen Cavalcanti, Simone Cecilio Hallak Regalo, Selma Siessere, Flavio Magno Goncalves, Cristiano Miranda de Araujo, Karinna Verissimo Meira Taveira
Summary: This study aimed to determine the prevalence of chewing difficulty in older people in long-term care. The meta-analysis found that approximately one in three older people in long-term care have difficulty in chewing. The results also indicated that sample size was an important factor in explaining the heterogeneity.
Article
Dentistry, Oral Surgery & Medicine
Yerko Leighton, Luis Carpio, Benjamin Weber, Fernando Jose Dias, Eduardo Borie
Summary: The clinical behavior of single extra-short 4-mm implants placed in the posterior mandible was evaluated during a 3-year follow-up. The survival rate of implants was 100% without any biologic complications, while one prosthetic complication was observed.
JOURNAL OF PROSTHETIC DENTISTRY
(2022)
Article
Neurosciences
Guilherme Gallo Costa Gomes, Marcelo Palinkas, Gabriel Padua da Silva, Camila Roza Goncalves, Robson Felipe Tosta Lopes, Edson Donizetti Verri, Saulo Cesar Vallin Fabrin, Evandro Marianetti Fioco, Selma Siessere, Simone Cecilio Hallak Regalo
Summary: The study evaluated the stomatognathic system of patients after hemorrhagic stroke, finding significant reductions in bite force on both affected and unaffected sides, as well as significant differences in temporal muscle thickness at mandibular rest.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2022)
Article
Polymer Science
Josefa Alarcon Apablaza, Maria Florencia Lezcano, Karina Godoy Sanchez, Gonzalo H. Oporto, Fernando Jose Dias
Summary: This scoping review summarizes the adequate quantitative/morphometric parameters of polymeric nerve guide conduits (NGCs) that provide a supportive environment for nerve regeneration. Optimal morphometric characteristics, such as wall thickness, fiber size, pore size, and porosity, are identified to enhance nerve regeneration and reduce the need for experimental studies.
Review
Polymer Science
Alex Lopez Marquez, Ivan Emilio Gareis, Fernando Jose Dias, Christoph Gerhard, Maria Florencia Lezcano
Summary: This review analyzes the effect of controlling fiber surface topography on cell-scaffold interactions in electrospun scaffolds based on in vitro studies. The results indicate that nanopores and roughness on fiber surfaces improve cell proliferation and adhesion. However, the quality of evidence varies for different cell-scaffold interactions and morphological attributes, calling for further research.
Review
Polymer Science
Alex Lopez Marquez, Ivan Emilio Gareis, Fernando Jose Dias, Christoph Gerhard, Maria Florencia Lezcano
Summary: Electrospun scaffolds are an important research direction in tissue engineering as they can imitate the hierarchical structures of the extracellular matrix. This article discusses the issues with commonly used methods for characterizing electrospun scaffolds and proposes more suitable imaging and physical measurement methods. The results show that imaging methods have the most benefits, with limitations only in terms of cost and expertise. By using more accurate characterization methods, researchers can gain a better understanding of the characteristics of electrospun scaffolds.
Review
Biology
Maria Florencia Lezcano, Giannina Alvarez, Priscila Chuhuaicura, Karina Godoy, Josefa Alarcon, Francisca Acevedo, Ivan Gareis, Fernando Jose Dias
Summary: Polyhydroxybutyrate (PHB) scaffolds show promising potential in promoting peripheral nerve regeneration, and the incorporation of additives appears to enhance nerve regeneration. However, standardized experimentation on animals is currently lacking in the reviewed studies, making it necessary to follow guidelines, improve study design, and enhance research quality.
Article
Multidisciplinary Sciences
Milena Rodrigues Carvalho, Simone Cecilio Hallak Regalo, Selma Siessere, Ligia Maria Napolitano Goncalves, Francisco Wanderley Garcia de Paula-Silva, Fernanda Vicioni-Marques, Paulo Nelson-Filho, Paulo Batista de Vasconcelos, Fabricio Kitazono de Carvalho, Alexandra Mussolino de Queiroz
Summary: Molar-incisor hypomineralization (MIH) is a dental enamel defect that affects first molars and incisor teeth, causing challenges in dental care. This study evaluated the functionality of the stomatognathic system in children with and without MIH and found that those with MIH have impaired muscle activity and functionality compared to the control group.
Article
Chemistry, Multidisciplinary
Maria Florencia Lezcano, Fernando Dias, Nicole Farfan-Beltran, Maria Cristina Manzanares-Cespedes, Camila Cerda, Ramon Fuentes
Summary: This study proposed and established a method to synchronize 3D Electromagnetic Articulography (3D-EMA) with Surface Electromyography (SEMG) based on the standard components of this equipment. The results showed that this method can effectively analyze mandibular movements and electromyographic activity, providing insights for the analysis of masticatory activity and its complexity in different clinical situations.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemistry & Molecular Biology
Glauce Crivelaro Nascimento, Gabrielle Jacob, Bruna Araujo Milan, Gabrielli Leal-Luiz, Bruno Lima Malzone, Airam Nicole Vivanco-Estela, Daniela Escobar-Espinal, Fernando Jose Dias, Elaine Del-Bel
Summary: The pathophysiologic mechanisms of the lateral pterygoid muscles (LPMs) and the trigeminal system related to Parkinson's Disease (PD)-induced orofacial manifestations were investigated. The study found that hemiparkinsonism increased slow skeletal myosin fibers in the LPMs, while in dyskinetic rats, these fibers decreased in the contralateral side of the lesion. Activation of the spinal trigeminal nucleus may be associated with orofacial sensorial impairment in Parkinsonian rats, while a fatigue profile on LPMs is suggested in L-DOPA-induced dyskinesia when the motor and facial nucleus are activated.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Karini Carvalho Costa, Camila Helena Ferreira Cuelho, Sonia Aparecida Figueiredo, Fernanda Maria Pinto Vilela, Maria Jose Vieira Fonseca
Summary: This study developed a topical formulation containing the purified fraction of I. edulis extract and investigated its skin penetration. In vitro and in vivo studies showed that the formulation had photoprotective and photochemopreventive potential. The purified fraction, rich in phenolic compounds, when incorporated in the formulation, can prevent UV-induced skin damage due to its antioxidant and anti-inflammatory properties.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2023)
Article
Anatomy & Morphology
Camila Venegas, Alain Arias, Fernando J. Dias, Ivonne Garay, Pablo Navarro, Ramon Fuentes
Summary: This study morphometrically characterized the mandible of rats using CBCT and identified differences between the left and right sides. The findings provide important references for research involving the rat mandible, such as studies on anesthetic techniques, orofacial pain, bone growth, and dental or periodontal tissue pathophysiology. The rat mandible serves as a valuable and feasible animal model.
INTERNATIONAL JOURNAL OF MORPHOLOGY
(2022)
