Article
Chemistry, Physical
Pier Paolo Poli, Lais Kawamata de Jesus, Ulisses Ribeiro Campos Dayube, Henrique Hadad, Caroline Loureiro, Fernando Yamamoto Chiba, Thayane Silveira Mata Furtado, Maisa Pereira Silva, Roberta Okamoto, Carlo Maiorana, Paulo Sergio Perri de Carvalho, Francisley Avila Souza
Summary: This study evaluates the effects of photobiomodulation therapy on the peri-implant bone healing of implants with different surface treatments. The results showed that PBM therapy had a significant positive effect on the machined surface implants.
Article
Biochemistry & Molecular Biology
Gagana Karkada, G. Arun Maiya, Praveen Arany, Mohandas Rao, Shalini Adiga, Shobha Ullas Kamath
Summary: The study aimed to investigate the effect of photobiomodulation therapy with a dosage of 4 J/cm(2) on diabetic neuropathic wound healing dynamics in Wistar rats and its relationship with oxidative stress markers. Results showed that photobiomodulation therapy improved wound healing speed and cellular responses, playing a positive role in the healing process of diabetic patients.
CELL BIOCHEMISTRY AND BIOPHYSICS
(2022)
Article
Multidisciplinary Sciences
Xiangli Zhang, Zhilong Wang, Hong Jiang, Huajing Zeng, Nan An, Bin Liu, Luyi Sun, Zengjie Fan
Summary: A self-powered enzyme-linked microneedle (MN) patch was designed and fabricated, consisting of glucose oxidase (GOx) and horseradish peroxidase (HRP) encapsulated in ZIF-8 nanoparticles within anode and cathode MN arrays. The enzymatic cascade reaction in the MN patch effectively reduced local hyperglycemia in diabetic wounds while generating stable microcurrents to promote rapid healing. Thus, the MN patch showed rapid, complete, and scar-preventative healing of diabetic wounds due to the synergistic actions of hypoglycemic, antibacterial, anti-inflammatory, and bioelectrical stimulation.
Article
Materials Science, Multidisciplinary
Marie-Leonor Touraton, Mickael Martin, Sylvain David, Nicolas Bernier, Nevine Rochat, Jeremy Moeyaert, Virginie Loup, Frederic Boeuf, Christophe Jany, Didier Dutartre, Thierry Baron
Summary: The study focused on metal organic chemical vapor deposition of AlGaAs on GaAs using selective epitaxial growth. It examined the growth and structural characteristics of AlGaAs layers on GaAs structures, and found that the selective growth of AlGaAs structures for red optical emission requires careful temperature tuning. The obtained layers are seen as excellent candidates for future red optical emitters directly integrated on a silicon wafer platform.
Review
Biochemistry & Molecular Biology
Vladyslav Vivcharenko, Marta Trzaskowska, Agata Przekora
Summary: Infections during wound healing are common complications in wound care that hinder the healing process and lead to non-healing wounds. Skin microbiota and the wound microenvironment contribute to the occurrence of skin infections, increasing morbidity and mortality rates. Effective treatment options, such as antimicrobial agents in wound dressings, have been found to reduce wound colonization and improve healing. This review paper discusses the impact of bacterial infections on wound healing phases and promising modifications of dressing materials, including antibiotics, nanoparticles, cationic organic agents, and plant-derived natural compounds, for antimicrobial wound dressings. The review article is based on scientific contributions from the PubMed database (supported with Google Scholar searching) over the past 5 years.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Analytical
Maksimas Anbinderis, Steponas Asmontas, Aurimas Cerskus, Jonas Gradauskas, Andzej Lucun, Aldis Silenas, Algirdas Suziedelis
Summary: The experimental studies on planar microwave diodes based on the n-AlxGa1-xAs layer grown on a semi-insulating GaAs substrate reveal their potential as reliable and inexpensive sensors of microwave radiation in the millimeter wavelength range. The detection properties of the diodes show a strong dependence on the AlAs mole fraction x, with significantly increased voltage responsivity at higher x values. Additionally, a model has been proposed to forecast the sensor's responsivity in other frequency ranges.
Article
Crystallography
Sonali Sharma, Mithra N. N. Hegde, Sindhu Ramesh
Summary: This study evaluated the compositional changes caused by different surface treatments on demineralized enamel. The results showed that using a 3.5 watts aluminum-gallium-arsenide laser and CPP-ACPF treatment could induce compositional changes in the organic and inorganic components of enamel tissues, similar to those of the control group. This suggests that aluminum-gallium-arsenide laser irradiation can enhance enamel remineralization.
Article
Nanoscience & Nanotechnology
Geun Won Gang, Jong Hoon Lee, Su Yeon Kim, Taehyeon Jeong, Kyung Bin Kim, Nguyen Thi Hong Men, Yu Ra Kim, Sang Jung Ahn, Chung Soo Kim, Young Heon Kim
Summary: In situ heating transmission electron microscopy was used to study the microstructural evolutions in self-catalyzed GaAs nanowires, showing morphological changes and atomic behavior at the interface. The process began at around 200 degrees C with formation and destruction of atomic layers, leading to Ga droplet depletion and rapid growth of zinc-blende GaAs structures above 300 degrees C. GaAs decomposition was observed at around 600 degrees C.
Review
Chemistry, Medicinal
Cristiano da Rosa, Ian Lucas Bueno, Ana Clara Martins Quaresma, Giovanna Barbarini Longato
Summary: Propolis, rich in phenolic compounds, has demonstrated antimicrobial, anti-inflammatory, analgesic, and angiogenesis promoter effects. Clinical studies have shown its potential as an alternative treatment for skin ulcers, but more research is needed to standardize its administration and concentration, as well as evaluate its safety and maximize therapeutic benefits.
Article
Engineering, Biomedical
Shin-Da Wu, Niann-Tzyy Dai, Chao-Yaug Liao, Lan-Ya Kang, Yu-Wen Tseng, Shan-hui Hsu
Summary: A bioprintable hydrogel has been developed for the treatment of chronic and irregular wounds. The hydrogel can be printed in both planar and curvilinear shapes, and has been shown to promote complete repair and regeneration in both types of wounds.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Multidisciplinary Sciences
So Yun Lee, Sangheon Jeon, Young Woo Kwon, Mina Kwon, Moon Sung Kang, Keum-Yong Seong, Tae-Eon Park, Seung Yun Yang, Dong-Wook Han, Suck Won Hong, Ki Su Kim
Summary: In this study, an adhesive hyaluronic acid-based gelatin nanofibrous membrane integrated with multiple light-emitting diode arrays was developed as a skin-attachable patch. Experimental results demonstrated that this medical device accelerated the wound healing process through the synergy of mimicking the extracellular matrix structure and LED irradiation.
Article
Chemistry, Physical
Yana Suchikova, Sergii Kovachov, Andriy Lazarenko, Ihor Bohdanov
Summary: This study reports the synthesis of heterostructure using a simple and inexpensive electrochemical deposition method. The result shows that nanocrystallites of the desert rose type were successfully synthesized on the surface of mono-GaAs. It is also discovered that the heterostructure has a soft transitional porous layer, ensuring good quality of nanostructures and adhesion to the crystal surface. Furthermore, the study indicates that GaAs can be an ideal substrate for growing the heterostructure.
APPLIED SURFACE SCIENCE ADVANCES
(2022)
Article
Nanoscience & Nanotechnology
Di Mei, Xiaolong Guo, Yirong Wang, Xiaofei Huang, Li Guo, Pengfei Zou, Delong Ge, Xinxin Wang, Wenhui Lee, Tongyi Sun, Zhiqin Gao, Yuanyuan Gao
Summary: The PGO-OH30 drug-delivery system, loaded with OH30, demonstrated good biocompatibility and excellent drug-delivery ability, accelerating wound healing and reducing the amount of S. aureus in infected wounds.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Optics
Gang Wang, Yiheng Liu, Xin Yan, Guilong Gao, Tao Wang, Lili Li, Yuetong Zhao, Jinbo Zhao, Kai He, Jinshou Tian
Summary: This study proposes a novel x-ray detection system that achieves a temporal resolution of 930 fs by utilizing photorefractive and four-wave mixing effects. The system consists of a signal-conversion system and a signal-acquisition system. The signal-conversion system is based on the photorefractive effect, converting x-ray evolution into the variation of infrared interference intensity. The signal-acquisition system includes a time-domain amplification system based on four-wave mixing and a high-resolution signal-recording system, providing a temporal resolution of 525 fs.
Article
Nutrition & Dietetics
Wenhao Hao, Huali Meng, Hui Li, Yan Zheng, Chunhong Song, Ziping Jiang, Xue Bai, Zhiyue Zhang, Lei Du, Pei Liu, Hao Wu
Summary: Diabetes impairs wound healing, but the local application of krill oil can accelerate diabetic wound healing by reversing inflammation, impaired collagen deposition, and suppressed neovascularization.
Article
Nutrition & Dietetics
Aline Rosignoli da Conceicao, Kelly A. Dias, Stephanie Michelin Santana Pereira, Luis Claudio Saraiva, Livya Alves Oliveira, Eliana Carla Gomes de Souza, Reggiani Vilela Goncalves, Sergio Luis Pinto da Matta, Antonio J. Natali, Hercia Stampini D. Martino, Ceres Mattos Della Lucia
Summary: The study showed that the combination of whey protein concentrate and curcumin can reduce blood glucose levels, oxidative damage, and inflammatory responses, which helps mitigate the effects of exhaustive physical exercise in swimming.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Veterinary Sciences
Barbara Cristina Felix Nogueira, Artur Kanadani Campos, Raul Santos Alves, Rita de Cassia Vieira Faria, Mariaurea Matias Sarandy, Fabyano Fonseca E. Silva, Reggiani Vilela Goncalves
Summary: This study analyzed the histopathological changes and oxidative profile responses of two breeds of horses infested with Amblyomma sculptum, finding a negative correlation between inflammatory response and tick infestation, as well as differences in antioxidant enzyme levels. The results suggest that animals with greater inflammatory response tend to have less tick infestation, and different levels of antioxidant enzymes may play a role in tissue damage and oxidative stress.
RESEARCH IN VETERINARY SCIENCE
(2021)
Article
Engineering, Biomedical
Iago Malta, Thamyris Moraes, Livia Elisei, Romulo Novaes, Giovane Galdino
Summary: The study explored the effects of ultrasound and photobiomodulation on osteoarthritis-induced nociception in mice, suggesting that chronic treatment with these modalities can decrease pain perception by inhibiting glial activation in the spinal cord, as well as reducing the release of TNF-alpha.
LASERS IN MEDICAL SCIENCE
(2022)
Review
Parasitology
Daniel S. S. Bastos, Adriana C. Silva, Romulo D. Novaes, Ana Claudia F. Souza, Eliziaria C. Santos, Reggiani Goncalves, Eduardo A. Marques-Da-Silva
Summary: This systematic review analyzed preclinical evidence on the effectiveness of drug combinations for treating visceral leishmaniasis (VL). The findings suggest that combination chemotherapy, particularly using classical drugs and new drugs, can lead to additive or synergistic effects in reducing parasite load and improving cure rates in VL.
Article
Biochemistry & Molecular Biology
Matheus Augusto Souza, Elda Goncalves-Santos, Reggiani Goncalves, Eliziaria C. Santos, Camila C. Campos, Marcos J. Marques, Raquel L. M. Souza, Romulo D. Novaes
Summary: The findings of this study indicate that doxycycline exacerbates lung granulomatous inflammation in a dose-dependent manner by promoting eosinophil infiltration and downregulating Th2 effectors, thereby reinforcing lipid and protein oxidative damage in chronic S. mansoni infection.
BIOMEDICAL JOURNAL
(2022)
Article
Parasitology
Diego F. Vilas-Boas, Raphaela R. G. Oliveira, Elda Goncalves-Santos, Luana S. Silva, Livia F. Diniz, Ana L. Mazzeti, Guilherme A. Brancaglion, Diogo T. Carvalho, Sergio Caldas, Romula D. Novaes, Ivo S. Caldas
Summary: The study demonstrates the protective effects of 4NB and Bz alone or in combination on acute myocarditis, reducing blood parasitism and inflammation.
Article
Nutrition & Dietetics
Andressa Ladeira Bernardes, Luis Fernando de Sousa Moraes, Bruna Cristina dos Santos Cruz, Lisiane Lopes da Conceicao, Leandro Licursi de Oliveira, Mariaurea Matias Sarandy, Reggiani Vilela Goncalves, Maria do Carmo Gouveia Peluzio
Summary: This study investigates the effects of supplementation with 5% and 10% dehydrated H. sabdariffa calyces (DHSC) on the development of pre-neoplastic lesions in mice. The results show that DHSC supplementation can reduce the formation of aberrant crypt foci (ACF) and have positive effects on liver enzyme activity and colon mucosa inflammation.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Anderson Castro Ribeiro, Robson Eugenio Silva, Patricia Braga Issa Justino, Eliziaria Cardoso Santos, Reggiani Vilela Goncalves, Romulo Dias Novaes
Summary: Hemodialysis patients are exposed to various risk factors, including malnutrition and cardio-metabolic issues. A longitudinal study found that while anthropometric and nutritional factors remained stable over time, biomarkers such as adipokines and cytokines showed high variability. Factors such as fat mass, creatinine, and urea were found to be predictive markers of this variability.
Article
Geriatrics & Gerontology
Margarida Pereira-Santos, Elda Goncalves-Santos, Matheus Augusto Souza, Ivo Santana Caldas, Graziela Domingues Almeida Lima, Reggiani Vilela Goncalves, Romulo Dias Novaes
Summary: Chronic pretreatment with rapamycin can attenuate immunosenescence in mice, contributing to prolonged parasite resistance and attenuated acute myocarditis in elderly hosts challenged by T. cruzi.
EXPERIMENTAL GERONTOLOGY
(2022)
Article
Pharmacology & Pharmacy
Cintia Oliveira Alves, Romulo Dias Novaes, Maria Tereza Carneiro Paschoal Bernardes, Reggiani Vilela Goncalves, Laila Pereira da Silva, Sandra Barbosa Neder Agostini, Gislaine Ribeiro Pereira, Flavia Chiva Carvalho
Summary: This study evaluated two MTX-loaded liquid crystals (C1CH and C1CHCE) as topical treatments for psoriasis. The results showed that these liquid crystals exhibited significant immunomodulatory effects and induced skin remodeling. They also reduced inflammation and regulated the activity of cytokines and enzymes associated with psoriasis.
JOURNAL OF PHARMACY AND PHARMACOLOGY
(2022)
Review
Medicine, Research & Experimental
Rodolfo C. Marcelino, Ronan M. Cardoso, Elisa L. B. C. Domingues, Reggiani Goncalves, Graziela D. A. Lima, Romulo D. Novaes
Summary: Plastic particle pollution can harm the reproductive system of mammals, leading to reduced fertility and reproductive organ diseases. This damage is caused by accumulation of plastic particles in the gonads, triggering oxidative and inflammatory reactions.
Review
Medicine, Research & Experimental
Thaiany Goulart De Souza-Silva, Isadora Azevedo Oliveira, Geovana Gabriele da Silva, Fabiana Cardoso Vilela Giusti, Romulo Dias Novaes, Hudsara Aparecida de Almeida Paula
Summary: This review systematically examines the effects of microplastics on the intestinal microbiota and morphofunctional changes of the intestinal mucosa in vivo. The findings suggest that microplastics may contribute to intestinal dysbiosis and structural changes in the intestinal mucosa.
Editorial Material
Cell Biology
Reggiani Vilela Goncalves, Mariaurea Matias Sarandy, Debora Esposito, Maria do Carmo Gouveia Peluzio
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2022)
Editorial Material
Cell Biology
Reggiani Vilela Goncalves, Mariella Bontempo Freitas, Debora Esposito
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2022)
