Journal
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
Volume 9, Issue 4, Pages 319-320Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.pdpdt.2012.06.005
Keywords
Photodynamic therapy; Nasopharyngeal carcinoma; Residual disease
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Local treatment of residual or recurrent nasopharyngeal carcinoma (NPC) is a challenge. Photodynamic therapy (PDT) is an established treatment modality for incurable head and neck carcinoma. Several studies reported induction of an immune response after PDT. We present a patient with residual T4N0M0 NPC who was treated with PDT for residual disease after initial treatment with neo-adjuvant chemotherapy and radiotherapy. Five years after PDT, the tumor did not progress and the patient is still in good condition. We discuss this remarkable Long-term response to PDT and speculate on possible mechanisms. (C) 2012 Elsevier B.V. All rights reserved.
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