Journal
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
Volume 184, Issue 7, Pages 1854-1865Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10426500802388318
Keywords
Bischalcones; microwave-irradiation; pyrazolines; ultrasound-irradiation
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Funding
- UGC, New Delhi
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N-1-acetyl-5-aryl-3-(substituted styryl) pyrazolines were synthesized by the cyclocondensation of 1,5-substituted diphenyl-1,4-pentadien-3-ones with hydrazine hydrate and a cyclizing agent such as acetic acid in ethanol. The title compounds were synthesized using conventional and solvent-free approaches, which involves mechanochemical mixing, microwave-irradiation, and ultrasound-irradiation methods in the presence of a solid support. The synthesized compounds have been characterized by elemental analyses and spectral data (IR, PMR, and FAB-mass). All the synthesized compounds have been evaluated for their antibacterial and antifungal activities. Some compounds have shown promising biological activity.
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