Article
Dermatology
Veronika Slonkova, Anna Vasku, Vladimir Vasku
Summary: This study investigated the relationship between polymorphisms in major proinflammatory genes and chronic venous disease (CVD) risk. Significant associations were found between certain gene polymorphisms and CVD phenotypes, such as arterial hypertension, ischaemic heart disease, and diabetes mellitus.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Review
Dermatology
Piyush Kumar, Ismat Ara Khan, Anupam Das, Hiral Shah
Summary: Chronic venous disease (CVD), a common condition in dermatology outpatient department, can progress to chronic leg ulcer if left untreated. It affects patients' quality of life and work productivity. The clinical manifestations range from asymptomatic varicose veins to ulceration and scarring. Increased venous hypertension and chronic inflammation play key roles in the development of CVD.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2022)
Article
Multidisciplinary Sciences
Min Yi Wong, Chien-Wei Chen, Yuan-Hsi Tseng, Shao-Kui Zhou, Yu-Hui Lin, Yao-Kuang Huang, Bor-Shyh Lin
Summary: In this study, TRANCE-MRI was used as a novel tool to objectively evaluate venous diseases without using contrast media. The QFlow analysis of parameters such as volume, flow, and velocity of greater saphenous veins could distinguish between patients and healthy controls. The RBFNN model successfully classified the morbid and normal limbs.
SCIENTIFIC REPORTS
(2023)
Article
Surgery
Ahmet Daylan, Fatih Islamoglu
Summary: Cyanoacrylate ablation (CAA) and radiofrequency ablation (RFA) show similar effectiveness in treating great saphenous vein (GSV) insufficiency, with CAA being more suitable for most patients due to its minimally invasive and nonthermal nature.
JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS
(2022)
Article
Surgery
Odette Hart, Sarah Adeane, Thodur Vasudevan, Bert van der Werf, Manar Khashram
Summary: Transcutaneous oxygenation in the lower limb, as measured by HSI, changes depending on the clinical component of the CEAP classification in CVD. Standing deoxyhemoglobin levels increase as the CEAP clinical class increases, particularly in the gaiter region.
JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS
(2022)
Article
Surgery
Sandra Vicente-Jimenez, Beatriz Lopez-Valcarcel, Manual Maynar, Elia Perez-Fernandez, Pilar Carrasco, Gil Rodriguez-Caravaca, Jose M. Navarro, Silvia Del Riego, Luis De Benito, Juan Fontcuberta
Summary: The study compares the outcomes of SS, RFA, and CAA treatments at 3 years, showing that all three techniques are cost-effective with an incremental cost-effectiveness ratio <30,000/QALY, suggesting recommendations for their use.
JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS
(2022)
Review
Medicine, Research & Experimental
Eliete Bouskela, Marzia Lugli, Andrew Nicolaides
Summary: Chronic venous disease (CVD) is expected to become increasingly important due to population aging and the rising prevalence of obesity. Micronised purified flavonoid fraction (MPFF), the most commonly used and widely studied venoactive drug (VAD), has been shown to effectively reduce symptoms and improve clinical outcomes in patients with CVD. Animal models and initial clinical research indicate that MPFF has anti-inflammatory and venotonic effects.
ADVANCES IN THERAPY
(2022)
Review
Medicine, General & Internal
Sally S. J. Chan, Yiu Che Chan, Stewart R. Walsh, Tze Tec Chong, Edward T. C. Choke, Alok Tiwari, Tjun Yip Tang
Summary: The use of CAG in Asian CVI patients has shown feasibility and good outcomes, with Singapore adopting CAG treatment for CVI with significant success. The variations in venous anatomy among Asian populations present new challenges for the application of CAG.
ANNALS ACADEMY OF MEDICINE SINGAPORE
(2021)
Article
Medicine, General & Internal
Cezary Szary, Justyna Wilczko, Dominika Plucinska, Anna Pachuta, Marcin Napierala, Anna Bodziony, Michal Zawadzki, Jerzy Leszczynski, Zbigniew Galazka, Tomasz Grzela
Summary: The study compared retrospective data from women with venous disease who had received treatment and those who had not. It found that previously treated patients had more advanced disease progression, but there were no significant differences between the two groups in terms of other aspects. The findings suggest the need to revise the treatment strategy to consider abdominal and pelvic veins as potential sources of reflux in female subjects.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Anjani H. Turaga
Summary: A hybrid treatment approach, involving endovenous laser ablation (EVLA), phlebectomy, and foam sclerotherapy, was used to successfully manage bilateral varicose veins in a 50-year-old female patient. The treatment plan consisted of two sessions of EVLA followed by two phlebectomies, and then four sessions of foam sclerotherapy. The patient experienced significant symptom improvement and positive cosmetic outcomes as a result of the treatment.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Review
Dermatology
Anupam Das, Abheek Sil, Piyush Kumar, Shekhar Neema
Summary: Chronic venous disease (CVD) is a common condition caused by venous hypertension of the limbs, and it can be diagnosed and managed through various approaches.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2022)
Article
Medicine, General & Internal
Angel Asunsolo, Chaowen Chen, Miguel A. Ortega, Santiago Coca, Luisa N. Borrell, Juan De Leon-Luis, Natalio Garcia-Honduvilla, Melchor Alvarez-Mon, Julia Bujan
Summary: The study found an association between varicose veins in women's lower extremities and/or pelvis and intrapartum fetal compromise, suggesting that varicose veins may be a novel and important clinical risk factor for fetal well-being and health.
FRONTIERS IN MEDICINE
(2021)
Review
Surgery
Arthur J. M. Lim, Abduraheem H. Mohamed, Louise H. Hitchman, Ross Lathan, Bharadhwaj Ravindhran, Misha M. Sidapra, George Smith, Ian C. Chetter, Daniel Carradice
Summary: This systematic review and meta-analysis compared the outcomes of mechanochemical ablation (MOCA) and endovenous thermal ablation (EVTA). MOCA had a lower rate of anatomical occlusion after 1 year and 2-3 years, but there was no difference in procedural and postprocedural pain.
BRITISH JOURNAL OF SURGERY
(2023)
Article
Health Care Sciences & Services
Eva Jambon, Yann Le Bras, Gregoire Cazalas, Nicolas Grenier, Clement Marcelin
Summary: The study evaluated indirect criteria of pelvic venous insufficiency using a short tau inversion recovery (STIR) sequence and compared the findings with phlebographic results. The results showed a correlation between the grading of left ovarian vein reflux on phlebography and the diameter of periuterine varicosities on STIR sequence. Periuterine varicosities were found to have a high positive predictive value for left ovarian reflux.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Health Care Sciences & Services
Oscar Fraile-Martinez, Cielo Garcia-Montero, Miguel Angel Alvarez-Mon, Ana M. Gomez-Lahoz, Jorge Monserrat, Maria Llavero-Valero, Fernando Ruiz-Grande, Santiago Coca, Melchor Alvarez-Mon, Julia Bujan, Natalio Garcia-Honduvilla, Jose Saz, Miguel A. Ortega
Summary: Chronic venous disease is a medical condition characterized by various disorders in the venous system, with varicose veins being a common manifestation. Previous studies have identified structural and functional changes in the venous wall, and metabolic alterations appear to play a crucial role in the pathogenesis of the disease. This study found increased expression of specific genes and proteins related to glycolysis in patients with chronic venous disease, suggesting a metabolic shift in the venous tissue.
JOURNAL OF PERSONALIZED MEDICINE
(2022)