Investigating the mechanistic basis of biomechanical input controlling skeletal development: exploring the interplay with Wnt signalling at the joint

Precise spatial restriction of BMP signaling in developing joints is perturbed upon loss of embryo movement

(2018) Pratik Narendra Pratap Singh et al.   DEVELOPMENT

Wnt signalling is a bi-directional vulnerability of cancer cells

(2016) David J. Duffy et al.   Oncotarget

Joint Development Involves a Continuous Influx of Gdf5-Positive Cells

(2016) Yulia Shwartz et al.   Cell Reports

Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation

(2015) A. Ray et al.   DEVELOPMENT

SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling

(2015) Kenji Kato et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone Homeostasis and Repair: Forced Into Shape

(2015) Alesha B. Castillo et al.   Current Rheumatology Reports

The importance of foetal movement for co-ordinated cartilage and bone development in utero

(2015) C. A. Shea et al.   Bone & Joint Research

Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways

(2014) Rebecca A Rolfe et al.   BMC GENOMICS

c-Jun is required for the specification of joint cell fates

(2013) A. Kan et al.   GENES & DEVELOPMENT

Improved Method forEx Ovo-Cultivation of Developing Chicken Embryos for Human Stem Cell Xenografts

(2013) Timo Schomann et al.   Stem Cells International

Mechanical Regulation of Skeletal Development

(2013) Rebecca Rolfe et al.   Current Osteoporosis Reports

Regeneration of the elbow joint in the developing chick embryo recapitulates development

(2012) B. Duygu Özpolat et al.   DEVELOPMENTAL BIOLOGY

Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development

(2012) Renée van Amerongen et al.   DEVELOPMENTAL BIOLOGY

Differential deployment of paralogous Wnt genes in the mouse and chick embryo during development

(2012) Audrey Martin et al.   EVOLUTION & DEVELOPMENT

Wntless functions in mature osteoblasts to regulate bone mass

(2012) Z. Zhong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biophysical stimuli induced by passive movements compensate for lack of skeletal muscle during embryonic skeletogenesis

(2011) Niamh C. Nowlan et al.   Biomechanics and Modeling in Mechanobiology

A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse

(2011) Anna Ferrer-Vaquer et al.   BMC DEVELOPMENTAL BIOLOGY

Mechanical Influences on Morphogenesis of the Knee Joint Revealed through Morphological, Molecular and Computational Analysis of Immobilised Embryos

(2011) Karen A. Roddy et al.   PLoS One

Dynamic patterns of mechanical stimulation co-localise with growth and cell proliferation during morphogenesis in the avian embryonic knee joint

(2010) Karen A. Roddy et al.   JOURNAL OF BIOMECHANICS

Developing bones are differentially affected by compromised skeletal muscle formation

(2009) Niamh C. Nowlan et al.   BONE

Muscle Contraction Is Necessary to Maintain Joint Progenitor Cell Fate

(2009) Joy Kahn et al.   DEVELOPMENTAL CELL

Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation

(2009) Florian Witte et al.   GENE EXPRESSION PATTERNS

3D representation of the developing chick knee joint: a novel approach integrating multiple components

(2009) Karen A. Roddy et al.   JOURNAL OF ANATOMY

Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation

(2008) S.-W. Cha et al.   DEVELOPMENT

A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis

(2008) Eiki Koyama et al.   DEVELOPMENTAL BIOLOGY

3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19)

(2008) Kristen Summerhurst et al.   GENE EXPRESSION PATTERNS

Identification of Mechanosensitive Genes during Embryonic Bone Formation

(2008) Niamh C. Nowlan et al.   PLoS Computational Biology

A dynamic pattern of mechanical stimulation promotes ossification in avian embryonic long bones

(2007) Niamh C. Nowlan et al.   JOURNAL OF BIOMECHANICS