Separate to operate: control of centrosome positioning and separation

Multiple Mechanisms Contribute to Centriole Separation in C. elegans

(2013) Gabriela Cabral et al.   CURRENT BIOLOGY

Kinesin-12 Differentially Affects Spindle Assembly Depending on Its Microtubule Substrate

(2013) Emma G. Sturgill et al.   CURRENT BIOLOGY

Cohesin cleavage is insufficient for centriole disengagement in Drosophila

(2013) Raquel A. Oliveira et al.   CURRENT BIOLOGY

EGF-Induced Centrosome Separation Promotes Mitotic Progression and Cell Survival

(2013) Balca R. Mardin et al.   DEVELOPMENTAL CELL

Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly

(2013) Yu-Chih Lin et al.   EMBO JOURNAL

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

(2013) F.-X. Yu et al.   GENES & DEVELOPMENT

G protein–coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor–promoted centrosomal separation

(2013) Christopher H. So et al.   MOLECULAR BIOLOGY OF THE CELL

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells

(2013) Marie-Laure Fogeron et al.   Nature Communications

LRRC45 Is a Centrosome Linker Component Required for Centrosome Cohesion

(2013) Runsheng He et al.   Cell Reports

Chromokinesins: localization-dependent functions and regulation during cell division

(2012) David Vanneste et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

It Takes KASH to Hitch to the SUN

(2012) Brian Burke   CELL

Structural insights into SUN-KASH complexes across the nuclear envelope

(2012) Wenjia Wang et al.   CELL RESEARCH

A kinesin-mediated mechanism that couples centrosomes to nuclei

(2012) Irina Tikhonenko et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Kendrin Is a Novel Substrate for Separase Involved in the Licensing of Centriole Duplication

(2012) Kazuhiko Matsuo et al.   CURRENT BIOLOGY

The Centrosome: A Target for Cancer Therapy

(2012) M. Mazzorana et al.   CURRENT CANCER DRUG TARGETS

Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation

(2012) Jonne A Raaijmakers et al.   EMBO JOURNAL

Phase II Study of the MEK1/MEK2 Inhibitor Trametinib in Patients With MetastaticBRAF-Mutant Cutaneous Melanoma Previously Treated With or Without a BRAF Inhibitor

(2012) Kevin B. Kim et al.   JOURNAL OF CLINICAL ONCOLOGY

Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations

(2012) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Functional Antagonism between Eg5 and Dynein in Spindle Bipolarization Is Not Compatible with a Simple Push-Pull Model

(2012) Stefan Florian et al.   Cell Reports

Rules of engagement: centrosome-nuclear connections in a closed mitotic system

(2012) M. Leo et al.   Biology Open

The Spatial Arrangement of Chromosomes during Prometaphase Facilitates Spindle Assembly

(2011) Valentin Magidson et al.   CELL

Plk1 Controls the Nek2A-PP1γ Antagonism in Centrosome Disjunction

(2011) Balca R. Mardin et al.   CURRENT BIOLOGY

KASH and SUN proteins

(2011) Daniel A. Starr   CURRENT BIOLOGY

Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1

(2011) Ewan Smith et al.   EMBO JOURNAL

Nek9 is a Plk1-activated kinase that controls early centrosome separation through Nek6/7 and Eg5

(2011) M Teresa Bertran et al.   EMBO JOURNAL

DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond

(2011) Péter Rapali et al.   FEBS Journal

DYNLL/LC8 Protein Controls Signal Transduction through the Nek9/Nek6 Signaling Module by Regulating Nek6 Binding to Nek9

(2011) Laura Regué et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The conversion of centrioles to centrosomes: essential coupling of duplication with segregation

(2011) Won-Jing Wang et al.   JOURNAL OF CELL BIOLOGY

Disconnecting the Golgi ribbon from the centrosome prevents directional cell migration and ciliogenesis

(2011) Lidia Hurtado et al.   JOURNAL OF CELL BIOLOGY

A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase

(2011) Stéphanie Bolhy et al.   JOURNAL OF CELL BIOLOGY

Timing of centrosome separation is important for accurate chromosome segregation

(2011) William T. Silkworth et al.   MOLECULAR BIOLOGY OF THE CELL

Cleavage of cohesin rings coordinates the separation of centrioles and chromatids

(2011) Laura Schöckel et al.   NATURE CELL BIOLOGY

Dual pathway spindle assembly increases both the speed and the fidelity of mitosis

(2011) K. Kaseda et al.   Biology Open

CDK5RAP2 Regulates Centriole Engagement and Cohesion in Mice

(2010) Jose A. Barrera et al.   DEVELOPMENTAL CELL

Mechanisms of Centrosome Separation and Bipolar Spindle Assembly

(2010) Marvin E. Tanenbaum et al.   DEVELOPMENTAL CELL

Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction

(2010) Balca R. Mardin et al.   NATURE CELL BIOLOGY

Mitotic functions of kinesin-5

(2010) Nick P. Ferenz et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulate Centrosome and Nuclear Positioning during Mitotic Entry

(2010) Daniël Splinter et al.   PLOS BIOLOGY

SUN-domain and KASH-domain proteins during development, meiosis and disease

(2009) A. Fridkin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Kif15 Cooperates with Eg5 to Promote Bipolar Spindle Assembly

(2009) Marvin E. Tanenbaum et al.   CURRENT BIOLOGY

The SUN Rises on Meiotic Chromosome Dynamics

(2009) Yasushi Hiraoka et al.   DEVELOPMENTAL CELL

Polo Kinase and Separase Regulate the Mitotic Licensing of Centriole Duplication in Human Cells

(2009) Meng-Fu Bryan Tsou et al.   DEVELOPMENTAL CELL

Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly

(2009) Alberto Toso et al.   JOURNAL OF CELL BIOLOGY

Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections

(2009) David Razafsky et al.   JOURNAL OF CELL BIOLOGY

Centrosomal Aki1 and cohesin function in separase-regulated centriole disengagement

(2009) Akito Nakamura et al.   JOURNAL OF CELL BIOLOGY

Asymmetric centrosome inheritance maintains neural progenitors in the neocortex

(2009) Xiaoqun Wang et al.   NATURE

SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice

(2009) Xiaochang Zhang et al.   NEURON

sSgo1, a Major Splice Variant of Sgo1, Functions in Centriole Cohesion Where It Is Regulated by Plk1

(2008) Xiaoxing Wang et al.   DEVELOPMENTAL CELL

sSgo1, a Guardian of Centriole Cohesion

(2008) William Y. Tsang et al.   DEVELOPMENTAL CELL

Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly

(2008) Marvin E Tanenbaum et al.   EMBO JOURNAL

A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization

(2008) Kyeongmi Kim et al.   EXPERIMENTAL CELL RESEARCH

Cohesin Associates with Spindle Poles in a Mitosis-specific Manner and Functions in Spindle Assembly in Vertebrate Cells

(2008) Xiangduo Kong et al.   MOLECULAR BIOLOGY OF THE CELL

Cohesin subunit SMC1 associates with mitotic microtubules at the spindle pole

(2008) R. W. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian NDR protein kinases: From regulation to a role in centrosome duplication

(2007) Alexander Hergovich et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS