The PAR network: redundancy and robustness in a symmetry-breaking system

PAR-2, LGL-1 and the CDC-42 GAP CHIN-1 act in distinct pathways to maintain polarity in the C. elegans embryo

(2013) A. Beatty et al.   DEVELOPMENT

Designing Synthetic Regulatory Networks Capable of Self-Organizing Cell Polarization

(2012) Angela H. Chau et al.   CELL

Centrosomes Can Initiate a Polarity Axis from Any Position within One-Cell C. elegans Embryos

(2012) Dominika Bienkowska et al.   CURRENT BIOLOGY

Anterior PAR proteins function during cytokinesis and maintain DYN-1 at the cleavage furrow inCaenorhabditis elegans

(2012) Kelly J. Pittman et al.   Cytoskeleton

The TAO kinase KIN-18 regulates contractility and establishment of polarity in the C. elegans embryo

(2012) Fabio M. Spiga et al.   DEVELOPMENTAL BIOLOGY

A Genome-Wide RNAi Screen for Enhancers of par Mutants Reveals New Contributors to Early Embryonic Polarity in Caenorhabditis elegans

(2012) D. G. Morton et al.   GENETICS

RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4

(2012) Yu Chung Tse et al.   MOLECULAR BIOLOGY OF THE CELL

RAB-5 Controls the Cortical Organization and Dynamics of PAR Proteins to Maintain C. elegans Early Embryonic Polarity

(2012) Vincent Hyenne et al.   PLoS One

Cell Polarity: Quantitative Modeling as a Tool in Cell Biology

(2012) A. Mogilner et al.   SCIENCE

Cell polarity: mechanochemical patterning

(2012) Nathan W. Goehring et al.   TRENDS IN CELL BIOLOGY

Deubiquitylation Machinery Is Required for Embryonic Polarity in Caenorhabditis elegans

(2012) Richard J. McCloskey et al.   PLoS Genetics

PAR-3 Oligomerization May Provide an Actin-Independent Mechanism to Maintain Distinct Par Protein Domains in the Early Caenorhabditis elegans Embryo

(2011) Adriana T. Dawes et al.   BIOPHYSICAL JOURNAL

Regulation of the MEX-5 Gradient by a Spatially Segregated Kinase/Phosphatase Cycle

(2011) Erik E. Griffin et al.   CELL

PAR-4/LKB1 Mobilizes Nonmuscle Myosin through Anillin to Regulate C. elegans Embryonic Polarization and Cytokinesis

(2011) Nicolas T. Chartier et al.   CURRENT BIOLOGY

Symmetry breaking and the establishment of cell polarity in budding yeast

(2011) Jayme M Johnson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The branched actin nucleator Arp2/3 promotes nuclear migrations and cell polarity in the C. elegans zygote

(2011) Huajiang Xiong et al.   DEVELOPMENTAL BIOLOGY

PAR proteins diffuse freely across the anterior–posterior boundary in polarizedC. elegansembryos

(2011) Nathan W. Goehring et al.   JOURNAL OF CELL BIOLOGY

Microtubules induce self-organization of polarized PAR domains in Caenorhabditis elegans zygotes

(2011) Fumio Motegi et al.   NATURE CELL BIOLOGY

Polarization of PAR Proteins by Advective Triggering of a Pattern-Forming System

(2011) N. W. Goehring et al.   SCIENCE

Cell Polarity in Eggs and Epithelia: Parallels and Diversity

(2010) Daniel St Johnston et al.   CELL

Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids

(2010) Katarina Moravcevic et al.   CELL

LGL Can Partition the Cortex of One-Cell Caenorhabditis elegans Embryos into Two Domains

(2010) Carsten Hoege et al.   CURRENT BIOLOGY

Membrane Targeting of Bazooka/PAR-3 Is Mediated by Direct Binding to Phosphoinositide Lipids

(2010) Michael P. Krahn et al.   CURRENT BIOLOGY

Cortical domain correction repositions the polarity boundary to match the cytokinesis furrow in C. elegans embryos

(2010) C. Schenk et al.   DEVELOPMENT

The C. elegans homolog of Drosophila Lethal giant larvae functions redundantly with PAR-2 to maintain polarity in the early embryo

(2010) A. Beatty et al.   DEVELOPMENT

Symmetry breaking and polarization of the C. elegans zygote by the polarity protein PAR-2

(2010) S. Zonies et al.   DEVELOPMENT

Different domains of C. elegans PAR-3 are required at different times in development

(2010) Bingsi Li et al.   DEVELOPMENTAL BIOLOGY

The PAM-1 aminopeptidase regulates centrosome positioning to ensure anterior–posterior axis specification in one-cell C. elegans embryos

(2010) Samantha M. Fortin et al.   DEVELOPMENTAL BIOLOGY

Binding to PKC-3, but not to PAR-3 or to a conventional PDZ domain ligand, is required for PAR-6 function in C. elegans

(2010) Jin Li et al.   DEVELOPMENTAL BIOLOGY

Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows

(2010) Mirjam Mayer et al.   NATURE

Reaction-Diffusion Model as a Framework for Understanding Biological Pattern Formation

(2010) S. Kondo et al.   SCIENCE

Dynamin Participates in the Maintenance of Anterior Polarity in the Caenorhabditis elegans Embryo

(2009) Yuji Nakayama et al.   DEVELOPMENTAL CELL

CGEF-1 and CHIN-1 Regulate CDC-42 Activity during Asymmetric Division in the Caenorhabditis elegans Embryo

(2009) Kraig T. Kumfer et al.   MOLECULAR BIOLOGY OF THE CELL

Symmetry Breaking in the Life Cycle of the Budding Yeast

(2009) B. D. Slaughter et al.   Cold Spring Harbor Perspectives in Biology

Modeling the Establishment of PAR Protein Polarity in the One-Cell C. elegans Embryo

(2008) Filipe Tostevin et al.   BIOPHYSICAL JOURNAL

Characterization of Protein Dynamics in Asymmetric Cell Division by Scanning Fluorescence Correlation Spectroscopy

(2008) Zdeněk Petrášek et al.   BIOPHYSICAL JOURNAL

PAR-6 levels are regulated by NOS-3 in a CUL-2 dependent manner in Caenorhabditiselegans

(2008) A. Pacquelet et al.   DEVELOPMENTAL BIOLOGY

The art and design of genetic screens: RNA interference

(2008) Michael Boutros et al.   NATURE REVIEWS GENETICS