Long-term depression-inducing stimuli promote cleavage of the synaptic adhesion molecule NGL-3 through NMDA receptors, matrix metalloproteinases and presenilin/ -secretase

Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases

(2013) Y. S. Yim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix Metalloproteinase Dependent Cleavage of Cell Adhesion Molecules in the Pathogenesis of CNS Dysfunction with HIV and Methamphetamine

(2012) Katherine Conant et al.   CURRENT HIV RESEARCH

The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses

(2012) Dilja D Krueger et al.   CURRENT OPINION IN NEUROBIOLOGY

MMP9: A novel function in synaptic plasticity

(2012) Magdalena Dziembowska et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Matrix metalloproteinase-3 in the central nervous system: a look on the bright side

(2012) Inge Van Hove et al.   JOURNAL OF NEUROCHEMISTRY

Synaptic cell adhesion molecule-2 and collapsin response mediator protein-2 are novel members of the matrix metalloproteinase-9 degradome

(2012) Malgorzata Bajor et al.   JOURNAL OF NEUROCHEMISTRY

Interleukin-1 Receptor Accessory Protein Organizes Neuronal Synaptogenesis as a Cell Adhesion Molecule

(2012) T. Yoshida et al.   JOURNAL OF NEUROSCIENCE

The leucine-rich repeat superfamily of synaptic adhesion molecules: LRRTMs and Slitrks

(2012) Jaewon Ko   MOLECULES AND CELLS

Selective control of inhibitory synapse development by Slitrk3-PTPδ trans-synaptic interaction

(2012) Hideto Takahashi et al.   NATURE NEUROSCIENCE

Synaptic circuit remodelling by matrix metalloproteinases in health and disease

(2012) George W. Huntley   NATURE REVIEWS NEUROSCIENCE

Transsynaptic Signaling by Activity-Dependent Cleavage of Neuroligin-1

(2012) Rui T. Peixoto et al.   NEURON

Activity-Dependent Proteolytic Cleavage of Neuroligin-1

(2012) Kunimichi Suzuki et al.   NEURON

Synaptic Cell Adhesion

(2012) M. Missler et al.   Cold Spring Harbor Perspectives in Biology

Molecular signals of plasticity at the tetrapartite synapse

(2011) Alexander Dityatev et al.   CURRENT OPINION IN NEUROBIOLOGY

Molecular organization and plasticity of the cytomatrix at the active zone

(2011) Eckart D Gundelfinger et al.   CURRENT OPINION IN NEUROBIOLOGY

The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2

(2011) Pamela Valnegri et al.   HUMAN MOLECULAR GENETICS

Influence of matrix metalloproteinase MMP-9 on dendritic spine morphology

(2011) P. Michaluk et al.   JOURNAL OF CELL SCIENCE

Enhanced neuronal plasticity and elevated endogenous sAPPα levels in mice over-expressing MMP9

(2011) Apostolia Fragkouli et al.   JOURNAL OF NEUROCHEMISTRY

IL-1 Receptor Accessory Protein-Like 1 Associated with Mental Retardation and Autism Mediates Synapse Formation by Trans-Synaptic Interaction with Protein Tyrosine Phosphatase  

(2011) T. Yoshida et al.   JOURNAL OF NEUROSCIENCE

Functional dependence of neuroligin on a new non-PDZ intracellular domain

(2011) Seth L Shipman et al.   NATURE NEUROSCIENCE

High Frequencies of De Novo CNVs in Bipolar Disorder and Schizophrenia

(2011) Dheeraj Malhotra et al.   NEURON

Postsynaptic TrkC and Presynaptic PTPσ Function as a Bidirectional Excitatory Synaptic Organizing Complex

(2011) Hideto Takahashi et al.   NEURON

Presenilin/γ-Secretase Regulates Neurexin Processing at Synapses

(2011) Carlos A. Saura et al.   PLoS One

Trans-Synaptic Interaction of GluRδ2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum

(2010) Takeshi Uemura et al.   CELL

Synaptic organizing complexes

(2010) Tabrez J Siddiqui et al.   CURRENT OPINION IN NEUROBIOLOGY

Synapse formation and maintenance by C1q family proteins: a new class of secreted synapse organizers

(2010) Michisuke Yuzaki   EUROPEAN JOURNAL OF NEUROSCIENCE

Organization of central synapses by adhesion molecules

(2010) Alexandra Tallafuss et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Secreted factors as synaptic organizers

(2010) Erin M. Johnson-Venkatesh et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Converting juvenile into adult plasticity: a role for the brain’s extracellular matrix

(2010) Eckart D. Gundelfinger et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus

(2010) Regina Dahlhaus et al.   HIPPOCAMPUS

Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases

(2010) Nathalie Bot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trans-synaptic Adhesions between Netrin-G Ligand-3 (NGL-3) and Receptor Tyrosine Phosphatases LAR, Protein-tyrosine Phosphatase δ (PTPδ), and PTPσ via Specific Domains Regulate Excitatory Synapse Formation

(2010) Seok-Kyu Kwon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methamphetamine-associated cleavage of the synaptic adhesion molecule intercellular adhesion molecule-5

(2010) Katherine Conant et al.   JOURNAL OF NEUROCHEMISTRY

Metzincin Proteases and Their Inhibitors: Foes or Friends in Nervous System Physiology?

(2010) S. Rivera et al.   JOURNAL OF NEUROSCIENCE

LRRTMs and Neuroligins Bind Neurexins with a Differential Code to Cooperate in Glutamate Synapse Development

(2010) T. J. Siddiqui et al.   JOURNAL OF NEUROSCIENCE

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

(2010) Alexander Dityatev et al.   NATURE REVIEWS NEUROSCIENCE

Molecular Mechanisms of Synaptic Specificity in Developing Neural Circuits

(2010) Megan E. Williams et al.   NEURON

SynCAM 1 Adhesion Dynamically Regulates Synapse Number and Impacts Plasticity and Learning

(2010) Elissa M. Robbins et al.   NEURON

Matrix metalloproteinase-dependent shedding of intercellular adhesion molecule-5 occurs with long-term potentiation

(2010) K. Conant et al.   NEUROSCIENCE

Input-specific synaptic plasticity in the amygdala is regulated by neuroligin-1 via postsynaptic NMDA receptors

(2010) S.-Y. Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cbln1 Is a Ligand for an Orphan Glutamate Receptor  2, a Bidirectional Synapse Organizer

(2010) K. Matsuda et al.   SCIENCE

Contributions of Matrix Metalloproteinases to Neural Plasticity, Habituation, Associative Learning and Drug Addiction

(2010) John W. Wright et al.   NEURAL PLASTICITY

Habituation-induced neural plasticity in the hippocampus and prefrontal cortex mediated by MMP-3

(2009) John W. Wright et al.   BEHAVIOURAL BRAIN RESEARCH

Synapse development and plasticity: roles of ephrin/Eph receptor signaling

(2009) Kwok-On Lai et al.   CURRENT OPINION IN NEUROBIOLOGY

Matrix metalloproteinase-9 reversibly affects the time course of NMDA-induced currents in cultured rat hippocampal neurons

(2009) Tomasz Gorkiewicz et al.   HIPPOCAMPUS

Presenilin 1 Affects Focal Adhesion Site Formation and Cell Force Generation via c-Src Transcriptional and Posttranslational Regulation

(2009) Dieter Waschbüsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic activity prompts γ-secretase–mediated cleavage of EphA4 and dendritic spine formation

(2009) Eiji Inoue et al.   JOURNAL OF CELL BIOLOGY

Matrix Metalloproteinase-9 Controls NMDA Receptor Surface Diffusion through Integrin  1 Signaling

(2009) P. Michaluk et al.   JOURNAL OF NEUROSCIENCE

The NGL family of leucine-rich repeat-containing synaptic adhesion molecules

(2009) Jooyeon Woo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes

(2009) J Elia et al.   MOLECULAR PSYCHIATRY

Trans-synaptic adhesion between NGL-3 and LAR regulates the formation of excitatory synapses

(2009) Jooyeon Woo et al.   NATURE NEUROSCIENCE

Synaptogenic Proteins and Synaptic Organizers: “Many Hands Make Light Work”

(2009) Nils Brose   NEURON

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

An Unbiased Expression Screen for Synaptogenic Proteins Identifies the LRRTM Protein Family as Synaptic Organizers

(2009) Michael W. Linhoff et al.   NEURON

LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation

(2009) Joris de Wit et al.   NEURON

LRRTM2 Functions as a Neurexin Ligand in Promoting Excitatory Synapse Formation

(2009) Jaewon Ko et al.   NEURON

Modulation of synaptic transmission and plasticity by cell adhesion and repulsion molecules

(2009) Alexander Dityatev et al.   Neuron Glia Biology

γ-Secretase in biology and medicine

(2009) Michael S. Wolfe   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Molecular Mechanisms of Presynaptic Differentiation

(2008) Yishi Jin et al.   Annual Review of Cell and Developmental Biology

Cadherins and synaptic plasticity

(2008) Chin-Yin Tai et al.   CURRENT OPINION IN CELL BIOLOGY

Signaling by synaptogenic molecules

(2008) Thomas Biederer et al.   CURRENT OPINION IN NEUROBIOLOGY

MMP-7 cleaves the NR1 NMDA receptor subunit and modifies NMDA receptor function

(2008) Arek Szklarczyk et al.   FASEB JOURNAL

Ephrin-B2-induced Cleavage of EphB2 Receptor Is Mediated by Matrix Metalloproteinases to Trigger Cell Repulsion

(2008) Kai-Ti Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Important role of matrix metalloproteinase 9 in epileptogenesis

(2008) Grzegorz M. Wilczynski et al.   JOURNAL OF CELL BIOLOGY

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome

(2008) Barbara Schormair et al.   NATURE GENETICS

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

mGluR1/5-Dependent Long-Term Depression Requires the Regulated Ectodomain Cleavage of Neuronal Pentraxin NPR by TACE

(2008) Richard W. Cho et al.   NEURON

Activity-Dependent Shedding of the NMDA Receptor Glycine Binding Site by Matrix Metalloproteinase 3: A PUTATIVE Mechanism of Postsynaptic Plasticity

(2008) Thorsten Pauly et al.   PLoS One

Synapse elimination accompanies functional plasticity in hippocampal neurons

(2008) N. Bastrikova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular proteolysis by matrix metalloproteinase-9 drives dendritic spine enlargement and long-term potentiation coordinately

(2008) X.-b. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals

(2008) Juhyun Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic Profiling of γ-Secretase Substrates and Mapping of Substrate Requirements

(2008) Matthew L Hemming et al.   PLOS BIOLOGY

Synaptic adhesion molecules and PSD-95

(2007) Kihoon Han et al.   PROGRESS IN NEUROBIOLOGY

Hippocampal MMP-3 elevation is associated with passive avoidance conditioning

(2007) Mikel L. Olson et al.   REGULATORY PEPTIDES

MMPs in the central nervous system: Where the good guys go bad

(2007) S AGRAWAL et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY