Endocannabinoids via CB1 receptors act as neurogenic niche cues during cortical development

Cannabinoid Receptors CB1and CB2Form Functional Heteromers in Brain

(2012) Lucía Callén et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G Protein-regulated Inducer of Neurite Outgrowth (GRIN) Modulates Sprouty Protein Repression of Mitogen-activated Protein Kinase (MAPK) Activation by Growth Factor Stimulation

(2012) Tracy Anh Hwangpo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cracking Down on Inhibition: Selective Removal of GABAergic Interneurons from Hippocampal Networks

(2012) F. Antonucci et al.   JOURNAL OF NEUROSCIENCE

Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids

(2012) E. Puighermanal et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Functional diversity on synaptic plasticity mediated by endocannabinoids

(2012) R. Cachope   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Receptor Heteromerization Expands the Repertoire of Cannabinoid Signaling in Rodent Neurons

(2012) Raphael Rozenfeld et al.   PLoS One

Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways

(2011) O Gomez et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoid CB1 receptors transactivate multiple receptor tyrosine kinases and regulate serine/threonine kinases to activate ERK in neuronal cells

(2011) George D Dalton et al.   BRITISH JOURNAL OF PHARMACOLOGY

Rheb1 Is Required for mTORC1 and Myelination in Postnatal Brain Development

(2011) Jia Zou et al.   DEVELOPMENTAL CELL

CB2Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling

(2011) Javier Palazuelos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Concerted Action of CB1 Cannabinoid Receptor and Deleted in Colorectal Cancer in Axon Guidance

(2011) A. Argaw et al.   JOURNAL OF NEUROSCIENCE

Loss of COUP-TFI Alters the Balance between Caudal Ganglionic Eminence- and Medial Ganglionic Eminence-Derived Cortical Interneurons and Results in Resistance to Epilepsy

(2011) S. Lodato et al.   JOURNAL OF NEUROSCIENCE

Diacylglycerol Lipase-  and -  Control Neurite Outgrowth in Neuro-2a Cells through Distinct Molecular Mechanisms

(2011) K.-M. Jung et al.   MOLECULAR PHARMACOLOGY

Mutations in ABHD12 Cause the Neurodegenerative Disease PHARC: An Inborn Error of Endocannabinoid Metabolism

(2010) Torunn Fiskerstrand et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery?

(2010) Tricia H Smith et al.   BRITISH JOURNAL OF PHARMACOLOGY

Requirement of cannabinoid CB1 receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections

(2010) Chia-Shan Wu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The constitutive production of the endocannabinoid 2-arachidonoylglycerol participates in oligodendrocyte differentiation

(2010) Oscar Gomez et al.   GLIA

CB1Cannabinoid Receptors Increase Neuronal Precursor Proliferation through AKT/Glycogen Synthase Kinase-3β/β-Catenin Signaling

(2010) Stefania Trazzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Subcellular Recruitment of Monoacylglycerol Lipase Generates Spatial Specificity of 2-Arachidonoyl Glycerol Signaling during Axonal Pathfinding

(2010) E. Keimpema et al.   JOURNAL OF NEUROSCIENCE

Selective Reduction of Cholecystokinin-Positive Basket Cell Innervation in a Model of Temporal Lobe Epilepsy

(2010) M. S. Wyeth et al.   JOURNAL OF NEUROSCIENCE

Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice

(2010) Y. Gao et al.   JOURNAL OF NEUROSCIENCE

CB1 and CB2 cannabinoid receptor expression during development and in epileptogenic developmental pathologies

(2010) E. Zurolo et al.   NEUROSCIENCE

Endocannabinoid Signaling and Long-Term Synaptic Plasticity

(2009) Boris D. Heifets et al.   Annual Review of Physiology

Origin, Early Commitment, Migratory Routes, and Destination of Cannabinoid Type 1 Receptor-Containing Interneurons

(2009) Yury M. Morozov et al.   CEREBRAL CORTEX

Intermediate Neuronal Progenitors (Basal Progenitors) Produce Pyramidal–Projection Neurons for All Layers of Cerebral Cortex

(2009) Tom Kowalczyk et al.   CEREBRAL CORTEX

Neurobiological consequences of maternal cannabis on human fetal development and its neuropsychiatric outcome

(2009) Didier Jutras-Aswad et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

The endocannabinoid system and the regulation of neural development: potential implications in psychiatric disorders

(2009) Ismael Galve-Roperh et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Cannabis use in pregnancy and early life and its consequences: animal models

(2009) Miriam Schneider   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Cannabis and psychosis/schizophrenia: human studies

(2009) Deepak Cyril D’Souza et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Cannabinoid 1 Receptor and Interleukin-6 Receptor Together Induce Integration of Protein Kinase and Transcription Factor Signaling to Trigger Neurite Outgrowth

(2009) Yana Zorina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

(2009) María Salazar et al.   JOURNAL OF CLINICAL INVESTIGATION

Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling

(2009) Emma Puighermanal et al.   NATURE NEUROSCIENCE

Epileptogenesis in the immature brain: emerging mechanisms

(2009) Sanjay N. Rakhade et al.   Nature Reviews Neurology

Endocannabinoid Signaling Is Required for Development and Critical Period Plasticity of the Whisker Map in Somatosensory Cortex

(2009) Lu Li et al.   NEURON

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Reduced Cortical Cannabinoid 1 Receptor Messenger RNA and Protein Expression in Schizophrenia

(2008) Stephen M. Eggan et al.   ARCHIVES OF GENERAL PSYCHIATRY

Divergent Effects of Genetic Variation in Endocannabinoid Signaling on Human Threat- and Reward-Related Brain Function

(2008) Ahmad R. Hariri et al.   BIOLOGICAL PSYCHIATRY

A cannabinoid analogue of Δ9-tetrahydrocannabinol disrupts neural development in chick

(2008) Delphine Psychoyos et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Mechanisms of Control of Neuron Survival by the Endocannabinoid System

(2008) Ismael Galve-Roperh et al.   CURRENT PHARMACEUTICAL DESIGN

The type 1 cannabinoid receptor is highly expressed in embryonic cortical projection neurons and negatively regulates neurite growthin vitro

(2008) Tania Vitalis et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Glutamatergic dysfunction in schizophrenia: From basic neuroscience to clinical psychopharmacology

(2008) Rodrigo D. Paz et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1knockout mice

(2008) Ester Aso et al.   JOURNAL OF NEUROCHEMISTRY

Downregulation of the CB1 Cannabinoid Receptor and Related Molecular Elements of the Endocannabinoid System in Epileptic Human Hippocampus

(2008) A. Ludanyi et al.   JOURNAL OF NEUROSCIENCE

Aspects of endocannabinoid signaling in periimplantation biology

(2008) Xiaofei Sun et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The endocannabinoid system modulates a transient TNF pathway that induces neural stem cell proliferation

(2008) Ana Rubio-Araiz et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner

(2008) Maria Beatriz Goncalves et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation

(2008) Sheona Watson et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Failure of neuronal homeostasis results in common neuropsychiatric phenotypes

(2008) Melissa B. Ramocki et al.   NATURE

Soothing the seizures of children

(2008) Beat Lutz et al.   NATURE MEDICINE

Dcx reexpression reduces subcortical band heterotopia and seizure threshold in an animal model of neuronal migration disorder

(2008) Jean-Bernard Manent et al.   NATURE MEDICINE

Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

(2008) István Katona et al.   NATURE MEDICINE

Malformations of Cortical Development

(2008) Trudy Pang et al.   NEUROLOGIST

Brain Neuronal CB2 Cannabinoid Receptors in Drug Abuse and Depression: From Mice to Human Subjects

(2008) Emmanuel S. Onaivi et al.   PLoS One

Epilepsy in Dcx Knockout Mice Associated with Discrete Lamination Defects and Enhanced Excitability in the Hippocampus

(2008) Marika Nosten-Bertrand et al.   PLoS One

Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning

(2008) J. Mulder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior

(2008) M. Bergami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth

(2008) K. D. Bromberg et al.   SCIENCE

Concise Review: Pax6 Transcription Factor Contributes to both Embryonic and Adult Neurogenesis as a Multifunctional Regulator

(2008) Noriko Osumi et al.   STEM CELLS

Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions

(2007) Z. De March et al.   NEUROSCIENCE