Off-Target Cannabinoid Effects Mediated by GPR55

The Endocannabinoid System and Pain

(2012) Josee Guindon et al.   CNS & Neurological Disorders-Drug Targets

Identification of the GPR55 Agonist Binding Site Using a Novel Set of High-Potency GPR55 Selective Ligands

(2011) Evangelia Kotsikorou et al.   BIOCHEMISTRY

GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils

(2011) Nariman A B Balenga et al.   CELL RESEARCH

The L- -Lysophosphatidylinositol/GPR55 System and Its Potential Role in Human Obesity

(2011) J. M. Moreno-Navarrete et al.   DIABETES

Modulation of l-α-Lysophosphatidylinositol/GPR55 Mitogen-activated Protein Kinase (MAPK) Signaling by Cannabinoids

(2011) Sharon Anavi-Goffer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans

(2011) Silvana Y Romero-Zerbo et al.   JOURNAL OF ENDOCRINOLOGY

Endocannabinoid content in fetal bovine sera — Unexpected effects on mononuclear cells and osteoclastogenesis

(2011) Janine Marazzi et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Pharmacology of GPR55 in Yeast and Identification of GSK494581A as a Mixed-Activity Glycine Transporter Subtype 1 Inhibitor and GPR55 Agonist

(2011) A. J. Brown et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor

(2011) Li Huang et al.   LABORATORY INVESTIGATION

Minireview: Recent Developments in the Physiology and Pathology of the Lysophosphatidylinositol-Sensitive Receptor GPR55

(2011) Christopher M. Henstridge et al.   MOLECULAR ENDOCRINOLOGY

The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55

(2011) Niklas Schuelert et al.   NEUROSCIENCE LETTERS

Lysophosphatidylinositol Causes Neurite Retraction via GPR55, G13 and RhoA in PC12 Cells

(2011) Yutaro Obara et al.   PLoS One

Is lipid signaling through cannabinoid 2 receptors part of a protective system?

(2011) P. Pacher et al.   PROGRESS IN LIPID RESEARCH

N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

(2010) Douglas McHugh et al.   BMC NEUROSCIENCE

Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and ‘cannabinoid-like’ receptors in small arteries

(2010) CJ Daly et al.   BRITISH JOURNAL OF PHARMACOLOGY

GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells

(2010) Alexander Bondarenko et al.   BRITISH JOURNAL OF PHARMACOLOGY

A role for L-α-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells

(2010) Lesley A Ford et al.   BRITISH JOURNAL OF PHARMACOLOGY

GPR55 ligands promote receptor coupling to multiple signalling pathways

(2010) Christopher M Henstridge et al.   BRITISH JOURNAL OF PHARMACOLOGY

CB2: a cannabinoid receptor with an identity crisis

(2010) Brady K Atwood et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lipid bilayer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55

(2010) Evangelia Kotsikorou et al.   CHEMISTRY AND PHYSICS OF LIPIDS

GPR55, a Lysophosphatidylinositol Receptor with Cannabinoid Sensitivity?

(2010) Tapio Nevalainen et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Requirement of cannabinoid CB1 receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections

(2010) Chia-Shan Wu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Rimonabant, a cannabinoid CB1 receptor antagonist, attenuates mechanical allodynia and counteracts oxidative stress and nerve growth factor deficit in diabetic mice

(2010) Francesca Comelli et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas

(2010) Nephi Stella   GLIA

Cannabinoids and the immune system: An overview

(2010) Radu Tanasescu et al.   IMMUNOBIOLOGY

The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment

(2010) Rudolf Schicho et al.   INFLAMMATORY BOWEL DISEASES

A Lipid Pathway for Ligand Binding Is Necessary for a Cannabinoid G Protein-coupled Receptor

(2010) Dow P. Hurst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential effects of lysophospholipids on exocytosis in rat PC12 cells

(2010) May-Thu Ma et al.   JOURNAL OF NEURAL TRANSMISSION

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition

(2010) María M Caffarel et al.   Molecular Cancer

Endocannabinoids Potentiate Synaptic Transmission through Stimulation of Astrocytes

(2010) Marta Navarrete et al.   NEURON

The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK

(2010) C Andradas et al.   ONCOGENE

The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation

(2010) R Piñeiro et al.   ONCOGENE

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

Pharmacological characterization of GPR55, a putative cannabinoid receptor

(2010) Haleli Sharir et al.   PHARMACOLOGY & THERAPEUTICS

Functional polymorphism in the GPR55 gene is associated with anorexia nervosa

(2010) Hiroki Ishiguro et al.   SYNAPSE

Differential changes in GPR55 during microglial cell activation

(2009) Maciej Pietr et al.   FEBS LETTERS

Lipid G Protein-coupled Receptor Ligand Identification Using β-Arrestin PathHunter™ Assay

(2009) Hong Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atypical Responsiveness of the Orphan Receptor GPR55 to Cannabinoid Ligands

(2009) Ankur Kapur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer

(2009) Z. Qamri et al.   MOLECULAR CANCER THERAPEUTICS

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

(2009) L. S. Whyte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The enigmatic pharmacology of GPR55

(2009) Ruth A. Ross   TRENDS IN PHARMACOLOGICAL SCIENCES

Loss of Cannabinoid Receptor 1 Accelerates Intestinal Tumor Growth

(2008) D. Wang et al.   CANCER RESEARCH

Cannabinoids for Cancer Treatment: Progress and Promise

(2008) S. Sarfaraz et al.   CANCER RESEARCH

Ligand-Binding Architecture of Human CB2 Cannabinoid Receptor: Evidence for Receptor Subtype-Specific Binding Motif and Modeling GPCR Activation

(2008) Ying Pei et al.   CHEMISTRY & BIOLOGY

Wiring and firing neuronal networks: endocannabinoids take center stage

(2008) Tibor Harkany et al.   CURRENT OPINION IN NEUROBIOLOGY

The GPR55 ligand l-α-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

(2008) Christopher M. Henstridge et al.   FASEB JOURNAL

Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression

(2008) M. Waldeck-Weiermair et al.   JOURNAL OF CELL SCIENCE

Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

(2008) István Katona et al.   NATURE MEDICINE

The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

(2008) Penny C. Staton et al.   PAIN

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

(2008) J. E. Lauckner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel cannabinoid receptors

(2007) A J Brown   BRITISH JOURNAL OF PHARMACOLOGY

The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects

(2007) D G Johns et al.   BRITISH JOURNAL OF PHARMACOLOGY

The orphan receptor GPR55 is a novel cannabinoid receptor

(2007) E Ryberg et al.   BRITISH JOURNAL OF PHARMACOLOGY