Irradiation induces glioblastoma cell senescence and senescence-associated secretory phenotype

Radiation-induced cellular senescence results from a slippage of long-term G2arrested cells into G1phase

(2013) Caiyong Ye et al.   CELL CYCLE

Optimization of tumor xenograft dissociation for the profiling of cell surface markers and nutrient transporters

(2013) Vincent Petit et al.   LABORATORY INVESTIGATION

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

(2013) Juan Carlos Acosta et al.   NATURE CELL BIOLOGY

Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats

(2013) Shie-Chau Liu et al.   NEURO-ONCOLOGY

Glioblastoma cancer stem cells: Role of the microenvironment and therapeutic targeting

(2012) Luca Persano et al.   BIOCHEMICAL PHARMACOLOGY

CXCL1/GROα increases cell migration and invasion of prostate cancer by decreasing fibulin-1 expression through NF-κB/HDAC1 epigenetic regulation

(2012) Po-Lin Kuo et al.   CARCINOGENESIS

Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end?

(2012) Shota Tanaka et al.   Nature Reviews Clinical Oncology

Secretome analysis of ionizing radiation-induced senescent cancer cells reveals that secreted RKIP plays a critical role in neighboring cell migration

(2012) Na-Kyung Han et al.   PROTEOMICS

Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity

(2011) Y. Chien et al.   GENES & DEVELOPMENT

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

In vitro and In vivo Radiation Sensitization of Human Tumor Cells by a Novel Checkpoint Kinase Inhibitor, AZD7762

(2010) J. B. Mitchell et al.   CLINICAL CANCER RESEARCH

Survival of Patients with Newly Diagnosed Glioblastoma Treated with Radiation and Temozolomide in Research Studies in the United States

(2010) S. A. Grossman et al.   CLINICAL CANCER RESEARCH

NF-κB and STAT3 signaling in glioma: targets for future therapies

(2010) George P Atkinson et al.   Expert Review of Neurotherapeutics

Chemokine (C-C Motif) Ligand 2 Engages CCR2+Stromal Cells of Monocytic Origin to Promote Breast Cancer Metastasis to Lung and Bone

(2009) Xin Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

New advances that enable identification of glioblastoma recurrence

(2009) Isaac Yang et al.   Nature Reviews Clinical Oncology

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY