Derivate isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/M cell cycle arrest and apoptosis

Chk1 and Wee1 control genotoxic-stress induced G2–M arrest in melanoma cells

(2015) Julio Vera et al.   CELLULAR SIGNALLING

The Effect of GADD45a on Furazolidone-Induced S-Phase Cell-Cycle Arrest in Human Hepatoma G2 Cells

(2015) Yu Sun et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Trifluridine Induces p53-Dependent Sustained G2 Phase Arrest with Its Massive Misincorporation into DNA and Few DNA Strand Breaks

(2015) K. Matsuoka et al.   MOLECULAR CANCER THERAPEUTICS

BRCA1 regulates transforming growth factor-β (TGF-β1) signaling through Gadd45a by enhancing the protein stability of Smad4

(2015) Dan Li et al.   Molecular Oncology

The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells

(2015) Carolina Simioni et al.   Oncotarget

MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression

(2015) Taewan Kim et al.   Oncotarget

Overexpression of the Transcription Factor MEF2D in Hepatocellular Carcinoma Sustains Malignant Character by Suppressing G2-M Transition Genes

(2014) L. Ma et al.   CANCER RESEARCH

Isocorydine Derivatives and Their Anticancer Activities

(2014) Mei Zhong et al.   MOLECULES

Growth arrest and DNA damage 45G down-regulation contributes to janus kinase/signal transducer and activator of transcription 3 activation and cellular senescence evasion in hepatocellular carcinoma

(2013) Li Zhang et al.   HEPATOLOGY

Ribonucleotide reductase M2B inhibits cell migration and spreading by early growth response protein 1-mediated phosphatase and tensin homolog/Akt1 pathway in hepatocellular carcinoma

(2013) Hua Tian et al.   HEPATOLOGY

GADD45 Proteins: Central Players in Tumorigenesis

(2012) R. E. Tamura et al.   CURRENT MOLECULAR MEDICINE

APRIL Binding to BCMA Activates a JNK2-FOXO3-GADD45 Pathway and Induces a G2/M Cell Growth Arrest in Liver Cells

(2012) G. Notas et al.   JOURNAL OF IMMUNOLOGY

Isocorydine Inhibits Cell Proliferation in Hepatocellular Carcinoma Cell Lines by Inducing G2/M Cell Cycle Arrest and Apoptosis

(2012) Hefen Sun et al.   PLoS One

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle

(2012) Shauna A Henley et al.   Cell Division

Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication

(2011) Asako Sakaue-Sawano et al.   BMC CELL BIOLOGY

Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin β1 signaling in human hepatocellular carcinoma

(2011) Hong Li et al.   HEPATOLOGY

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE