Genetic variants associated with methotrexate efficacy and toxicity in early rheumatoid arthritis: results from the treatment of early aggressive rheumatoid arthritis trial

A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: The Treatment of Early Aggressive Rheumatoid Arthritis trial

(2012) Larry W. Moreland et al.   ARTHRITIS AND RHEUMATISM

Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma

(2011) Barbara Faganel Kotnik et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis

(2011) Thierry Dervieux et al.   Pharmacogenetics and Genomics

Predictors of response to methotrexate in early DMARD naive rheumatoid arthritis: results from the initial open-label phase of the SWEFOT trial

(2010) S. Saevarsdottir et al.   ANNALS OF THE RHEUMATIC DISEASES

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

(2010) J. S. Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Association screening of common and rare genetic variants by penalized regression

(2010) H. Zhou et al.   BIOINFORMATICS

Predictors of Clinical Response and Radiographic Progression in Patients with Rheumatoid Arthritis Treated with Methotrexate Monotherapy

(2010) J. DROUIN et al.   JOURNAL OF RHEUMATOLOGY

Methotrexate catabolism to 7-hydroxymethotrexate in rheumatoid arthritis alters drug efficacy and retention and is reduced by folic acid supplementation

(2009) Joseph E. Baggott et al.   ARTHRITIS AND RHEUMATISM

Genome-wide association analysis by lasso penalized logistic regression

(2009) Tong Tong Wu et al.   BIOINFORMATICS

Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects

(2009) Lisa R. Treviño et al.   JOURNAL OF CLINICAL ONCOLOGY

Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians

(2009) Shruti Sharma et al.   Pharmacogenetics and Genomics

American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis

(2008) Kenneth G. Saag et al.   ARTHRITIS AND RHEUMATISM

Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism

(2008) Petra Bohanec Grabar et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY