Pharmacogenomics of phase II metabolizing enzymes and drug transporters: clinical implications

Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of Breast Cancer and Chemotherapy Failure

(2011) Yu Toyoda et al.   Anti-Cancer Agents in Medicinal Chemistry

OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies

(2011) Megan Roth et al.   BRITISH JOURNAL OF PHARMACOLOGY

Single nucleotide polymorphisms of ABCC5 and ABCG1 transporter genes correlate to irinotecan-associated gastrointestinal toxicity in colorectal cancer patients: A DMET microarray profiling study

(2011) Maria Teresa Di Martino et al.   CANCER BIOLOGY & THERAPY

Pharmacokinetic Impact of SLCO1A2 Polymorphisms on Imatinib Disposition in Patients With Chronic Myeloid Leukemia

(2011) Y Yamakawa et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genetic Polymorphisms of ATP-Binding Cassette Transporters ABCB1 and ABCC2 and their Impact on Drug Disposition

(2011) Vincent Haufroid   CURRENT DRUG TARGETS

Part 2: Pharmacogenetic Variability in Drug Transport and Phase I Anticancer Drug Metabolism

(2011) M. J. Deenen et al.   ONCOLOGIST

Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake

(2011) M. Niemi et al.   PHARMACOLOGICAL REVIEWS

The evolution of the OATP hepatic uptake transport protein family in DMPK sciences: from obscure liver transporters to key determinants of hepatobiliary clearance

(2011) Katherine S. Fenner et al.   XENOBIOTICA

Structure and Function of the Human Breast Cancer Resistance Protein (BCRP/ABCG2)

(2010) Zhanglin Ni et al.   CURRENT DRUG METABOLISM

New Pharmacogenomic Paradigm in Breast Cancer Treatment

(2010) Kenneth Offit et al.   JOURNAL OF CLINICAL ONCOLOGY

Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON–TIMI 38 trial: a pharmacogenetic analysis

(2010) Jessica L Mega et al.   LANCET

Characterization of 17-dihydroexemestane glucuronidation: potential role of the UGT2B17 deletion in exemestane pharmacogenetics

(2010) Dongxiao Sun et al.   Pharmacogenetics and Genomics

Irinotecan pharmacogenomics

(2010) Sharon Marsh et al.   PHARMACOGENOMICS

Pharmacogenomics of membrane transporters: past, present and future

(2010) Sook Wah Yee et al.   PHARMACOGENOMICS

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

(2010) C. D. Klaassen et al.   PHARMACOLOGICAL REVIEWS

Genetic Causes of Clopidogrel Nonresponsiveness: Which Ones Really Count?

(2010) Kathryn M Momary et al.   PHARMACOTHERAPY

Influence of drug-transporter polymorphisms on the pharmacokinetics of fexofenadine enantiomers

(2010) Yumiko Akamine et al.   XENOBIOTICA

Impact of OATP transporters on pharmacokinetics

(2009) A Kalliokoski et al.   BRITISH JOURNAL OF PHARMACOLOGY

Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer treated with irinotecan? An evidence-based review

(2009) Glenn E Palomaki et al.   GENETICS IN MEDICINE

Hepatic drug transporters, old and new: Pharmacogenomics, drug response, and clinical relevance

(2009) Marianne K. DeGorter et al.   HEPATOLOGY

Comprehensive Pharmacogenetic Analysis of Irinotecan Neutropenia and Pharmacokinetics

(2009) Federico Innocenti et al.   JOURNAL OF CLINICAL ONCOLOGY

Pharmacogenetics of Membrane Transporters: An Update on Current Approaches

(2009) Tristan M. Sissung et al.   MOLECULAR BIOTECHNOLOGY

Methods for analysis in pharmacogenomics: lessons from the Pharmacogenetics Research Network Analysis Group

(2009) Balaji S Srinivasan et al.   PHARMACOGENOMICS

Fulfilling the Promise of Personalized Medicine? Systematic Review and Field Synopsis of Pharmacogenetic Studies

(2009) Michael V. Holmes et al.   PLoS One

Substrates and Inhibitors of Human Multidrug Resistance Associated Proteins and the Implications in Drug Development

(2008) Shu-Feng Zhou et al.   CURRENT MEDICINAL CHEMISTRY

Organic Cation Transporters and their Pharmacokinetic and Pharmacodynamic Consequences

(2008) Min-Koo Choi et al.   Drug Metabolism and Pharmacokinetics

Cytochrome P-450 Polymorphisms and Response to Clopidogrel

(2008) Jessica L. Mega et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic Determinants of Response to Clopidogrel and Cardiovascular Events

(2008) Tabassome Simon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Physiology, structure, and regulation of the cloned organic anion transporters

(2008) C. Srimaroeng et al.   XENOBIOTICA