Polymorphisms, hypertension and thiazide diuretics

Interaction of ACE and CYP11B2 Genes on Blood Pressure Response to Hydrochlorothiazide in Han Chinese Hypertensive Patients

(2011) Yun Li et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Genetic variation in renin predicts the effects of thiazide diuretics

(2011) Chin-Chou Huang et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Heterogeneity in antihypertensive treatment discontinuation between drugs belonging to the same class

(2011) Giuseppe Mancia et al.   JOURNAL OF HYPERTENSION

Association of Intergenic Polymorphism of Organic Anion Transporter 1 and 3 Genes With Hypertension and Blood Pressure Response to Hydrochlorothiazide

(2010) Y.-F. Han et al.   AMERICAN JOURNAL OF HYPERTENSION

Genetics of primary hypertension: The clinical impact of adducin polymorphisms

(2010) Lorena Citterio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Microalbuminuria Is a Predictor of Chronic Renal Insufficiency in Patients without Diabetes and with Hypertension: The MAGIC Study

(2010) F. Viazzi et al.   Clinical Journal of the American Society of Nephrology

Endogenous ouabain and the renin–angiotensin–aldosterone system: distinct effects on Na handling and blood pressure in human hypertension

(2010) Paolo Manunta et al.   JOURNAL OF HYPERTENSION

The Hypertensive Heart

(2010) Subha V. Raman   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

 -Adducin Stimulates the Thiazide-sensitive NaCl Cotransporter

(2010) H. Dimke et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lack of association between polymorphisms in STK39, a putative thiazide response gene, and blood pressure response to hydrochlorothiazide

(2010) Julio D. Duarte et al.   Pharmacogenetics and Genomics

Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients

(2010) Maximilian T. Lobmeyer et al.   Pharmacogenetics and Genomics

Pharmacogenomics of antihypertensive drugs: past, present and future

(2010) Julie A Johnson   PHARMACOGENOMICS

Adducin- and Ouabain-Related Gene Variants Predict the Antihypertensive Activity of Rostafuroxin, Part 1: Experimental Studies

(2010) M. Ferrandi et al.   Science Translational Medicine

Adducin- and Ouabain-Related Gene Variants Predict the Antihypertensive Activity of Rostafuroxin, Part 2: Clinical Studies

(2010) C. Lanzani et al.   Science Translational Medicine

Pharmacogenomics of antihypertensive drugs: Rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study

(2009) Julie A. Johnson et al.   AMERICAN HEART JOURNAL

Upregulation of Na+ and Ca2+ transporters in arterial smooth muscle from ouabain-induced hypertensive rats

(2009) Maria V. Pulina et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Has pharmacogenetics brought us closer to ‘personalized medicine’ for initial drug treatment of hypertension?

(2009) Donna K Arnett et al.   CURRENT OPINION IN CARDIOLOGY

A Functional Variant of NEDD4L Is Associated With Hypertension, Antihypertensive Response, and Orthostatic Hypotension

(2009) Fang Luo et al.   HYPERTENSION

Left ventricular geometry and endogenous ouabain in a Flemish population

(2009) Tatiana Kuznetsova et al.   JOURNAL OF HYPERTENSION

The Year in Hypertension

(2009) Bryan Williams   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

The Hypertension Paradox — More Uncontrolled Disease despite Improved Therapy

(2009) Aram V. Chobanian   NEW ENGLAND JOURNAL OF MEDICINE

Renin–Angiotensin System and α-Adducin Gene Polymorphisms and Their Relation to Responses to Antihypertensive Drugs: Results From the GENRES Study

(2008) Timo Suonsyrjä et al.   AMERICAN JOURNAL OF HYPERTENSION

Genomic Association Analysis Suggests Chromosome 12 Locus Influencing Antihypertensive Response to Thiazide Diuretic

(2008) Stephen T. Turner et al.   HYPERTENSION

Physiological Interaction Between α-Adducin and WNK1-NEDD4L Pathways on Sodium-Related Blood Pressure Regulation

(2008) Paolo Manunta et al.   HYPERTENSION

Effects of genetic variation in adducin on left ventricular diastolic function as assessed by tissue Doppler imaging in a Flemish population

(2008) Tatiana Kuznetsova et al.   JOURNAL OF HYPERTENSION

Interaction between the Gly460Trp α-adducin gene variant and diuretics on the risk of myocardial infarction

(2008) Diane BMA van Wieren-de Wijer et al.   JOURNAL OF HYPERTENSION

Endogenous ouabain in cardiovascular function and disease

(2008) Paolo Manunta et al.   JOURNAL OF HYPERTENSION

Variations in DNA elucidate molecular networks that cause disease

(2008) Yanqing Chen et al.   NATURE

Targeting and tinkering with interaction networks

(2008) Robert B Russell et al.   Nature Chemical Biology

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology

Whole-genome association study identifies STK39 as a hypertension susceptibility gene

(2008) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA