Pharmacogenomic biomarkers: validation needed for both the molecular genetic mechanism and clinical effect

Pharmacogenomics of the RNA World: Structural RNA Polymorphisms in Drug Therapy

(2011) W Sadee et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Nicotinic α5 receptor subunit mRNA expression is associated with distant 5′ upstream polymorphisms

(2010) Ryan M Smith et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Intronic Polymorphisms Affecting Alternative Splicing of Human Dopamine D2 Receptor Are Associated with Cocaine Abuse

(2010) Robert A Moyer et al.   NEUROPSYCHOPHARMACOLOGY

RNA and Disease

(2009) Thomas A. Cooper et al.   CELL

Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing

(2009) Graham A. Heap et al.   HUMAN MOLECULAR GENETICS

Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression

(2009) Neil Risch et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Global patterns of cis variation in human cells revealed by high-density allelic expression analysis

(2009) Bing Ge et al.   NATURE GENETICS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measuring cis-acting regulatory variants genome-wide: new insights into expression genetics and disease susceptibility

(2009) Wolfgang Sadee   Genome Medicine

Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement

(2008) D. Wang et al.   BLOOD

Promoter Polymorphisms in ACE (Angiotensin I–Converting Enzyme) Associated With Clinical Outcomes in Hypertension

(2008) AD Johnson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues

(2008) Andrew D. Johnson et al.   Pharmacogenetics and Genomics