Toxicogenetics: population-based testing of drug and chemical safety in mouse models

Detection, Validation, and Downstream Analysis of Allelic Variation in Gene Expression

(2009) D. C. Ciobanu et al.   GENETICS

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

(2009) A. H. Harrill et al.   GENOME RESEARCH

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Molecular networks as sensors and drivers of common human diseases

(2009) Eric E. Schadt   NATURE

A network view of disease and compound screening

(2009) Eric E. Schadt et al.   NATURE REVIEWS DRUG DISCOVERY

Genomewide Association Studies — Illuminating Biologic Pathways

(2009) Joel N. Hirschhorn   NEW ENGLAND JOURNAL OF MEDICINE

Genomewide Association Studies and Human Disease

(2009) John Hardy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacogenomics of adverse drug reactions: practical applications and perspectives

(2009) Laurent Becquemont   PHARMACOGENOMICS

Systems biology in pharmacogenomic research: the way to personalized prescribing?

(2009) Ellen S Koster et al.   PHARMACOGENOMICS

Drug-induced liver injury: insights from genetic studies

(2009) Raúl J Andrade et al.   PHARMACOGENOMICS

Pharmacogenomic Discovery Using Cell-Based Models

(2009) M. Welsh et al.   PHARMACOLOGICAL REVIEWS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Population-Based Discovery of Toxicogenomics Biomarkers for Hepatotoxicity Using a Laboratory Strain Diversity Panel

(2009) Alison H. Harrill et al.   TOXICOLOGICAL SCIENCES

Accurate Discovery of Expression Quantitative Trait Loci Under Confounding From Spurious and Genuine Regulatory Hotspots

(2008) H. M. Kang et al.   GENETICS

Naive Application of Permutation Testing Leads to Inflated Type I Error Rates

(2008) G. A. Churchill et al.   GENETICS

Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants

(2008) K. L. Mohlke et al.   HUMAN MOLECULAR GENETICS

An imputed genotype resource for the laboratory mouse

(2008) Jin P. Szatkiewicz et al.   MAMMALIAN GENOME

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

(2008) Elissa J. Chesler et al.   MAMMALIAN GENOME

Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: Current and developing technologies

(2008) B CHORLEY et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Progress and prospects in rat genetics: a community view

(2008) Timothy J Aitman et al.   NATURE GENETICS

Multiple Genetic Loci for Bone Mineral Density and Fractures

(2008) Unnur Styrkarsdottir et al.   NEW ENGLAND JOURNAL OF MEDICINE

HLA-B*5701 Screening for Hypersensitivity to Abacavir

(2008) Simon Mallal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mouse Phenome Database

(2008) S. C. Grubb et al.   NUCLEIC ACIDS RESEARCH

Genome-wide approaches to identify pharmacogenetic contributions to adverse drug reactions

(2008) M R Nelson et al.   PHARMACOGENOMICS JOURNAL

Mapping the Genetic Architecture of Gene Expression in Human Liver

(2008) Eric E Schadt et al.   PLOS BIOLOGY

Genetical Genomics: Spotlight on QTL Hotspots

(2008) Rainer Breitling et al.   PLoS Genetics

Genetic determinants of drug response in heart failure

(2008) Brian D. Lowes et al.   Current Cardiology Reports

Reciprocal Congenic Lines of Mice Capture theAliq1Effect on Acute Lung Injury Survival Time

(2007) Daniel R. Prows et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pathway analysis tools and toxicogenomics reference databases for risk assessment

(2007) Brigitte Ganter et al.   PHARMACOGENOMICS