Association of genetic variation in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein genes with the gastrointestinal side effects and lower BMI in metformin-treated type 2 diabetes patients

Mechanisms for membrane transport of metformin in human intestinal epithelial Caco-2 cells

(2011) Asuka Horie et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

A Common 5′-UTR Variant in MATE2-K Is Associated With Poor Response to Metformin

(2011) J H Choi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Mammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics

(2011) Katja Damme et al.   DRUG METABOLISM REVIEWS

The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c

(2011) Mette M.H. Christensen et al.   Pharmacogenetics and Genomics

Proton Pump Inhibitors Inhibit Metformin Uptake by Organic Cation Transporters (OCTs)

(2011) Anne T. Nies et al.   PLoS One

Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program

(2010) K. A. Jablonski et al.   DIABETES

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

(2010) Kaixin Zhou et al.   NATURE GENETICS

Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions

(2010) G Ahlin et al.   PHARMACOGENOMICS JOURNAL

Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI

(2009) Ineta Kalnina et al.   BMC Medical Genetics

Contribution of Organic Cation Transporter 2 (OCT2) to Cisplatin-Induced Nephrotoxicity

(2009) K K Filipski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin

(2009) M V Tzvetkov et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genetic Variation in the Multidrug and Toxin Extrusion 1 Transporter Protein Influences the Glucose-Lowering Effect of Metformin in Patients With Diabetes: A Preliminary Study

(2009) M. L. Becker et al.   DIABETES

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

(2009) Anne T. Nies et al.   HEPATOLOGY

Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response

(2009) Matthijs L. Becker et al.   Pharmacogenetics and Genomics

Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus

(2009) M L Becker et al.   PHARMACOGENOMICS JOURNAL

Structural Requirements for Drug Inhibition of the Liver Specific Human Organic Cation Transport Protein 1

(2008) Gustav Ahlin et al.   JOURNAL OF MEDICINAL CHEMISTRY

10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes

(2008) Rury R. Holman et al.   NEW ENGLAND JOURNAL OF MEDICINE