Balancing benefit and risk of medicines: a systematic review and classification of available methodologies

A Benefit-risk Model to Facilitate DMC-sponsor Communication and Decision Making

(2015) Andreas Sashegyi   DRUG INFORMATION JOURNAL

Quantitative Benefit-Risk Analysis for Evaluating Drug Therapies

(2013) Ralph L. Kodell et al.   Journal of Biopharmaceutical Statistics

A Decision-Analysis Tool for Benefit-Risk Assessment of Nonprescription Drugs

(2013) Eric P. Brass et al.   JOURNAL OF CLINICAL PHARMACOLOGY

A framework for organizing and selecting quantitative approaches for benefit-harm assessment

(2012) Milo A Puhan et al.   BMC Medical Research Methodology

Risk-Benefit Analysis of Seafood Consumption: A Review

(2012) Rosalee S. Hellberg et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

ADDIS: A decision support system for evidence-based medicine

(2012) Gert van Valkenhoef et al.   DECISION SUPPORT SYSTEMS

Improving the Decision-Making Process for Nonprescription Drugs: A Framework for Benefit–Risk Assessment

(2011) E P Brass et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

State of the art in benefit–risk analysis: Food microbiology

(2011) S.H. Magnússon et al.   FOOD AND CHEMICAL TOXICOLOGY

Multicriteria benefit–risk assessment using network meta-analysis

(2011) Gert van Valkenhoef et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Population Impact Analysis: a framework for assessing the population impact of a risk or intervention

(2011) A. Verma et al.   JOURNAL OF PUBLIC HEALTH

Statistical aspects in comparative benefit-risk assessment: challenges and opportunities for pharmaceutical statisticians

(2011) George Quartey et al.   PHARMACEUTICAL STATISTICS

A stochastic multicriteria model for evidence-based decision making in drug benefit-risk analysis

(2011) Tommi Tervonen et al.   STATISTICS IN MEDICINE

Application of the BRAT Framework to Case Studies: Observations and Insights

(2010) B S Levitan et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Development of a Framework for Enhancing the Transparency, Reproducibility and Communication of the Benefit–Risk Balance of Medicines

(2010) P M Coplan et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Bayesian networks

(2010) Adnan Darwiche   COMMUNICATIONS OF THE ACM

Benefit–risk assessment: the use of clinical utility index

(2010) Daniele Ouellet   Expert Opinion On Drug Safety

BRAFO tiered approach for benefit–risk assessment of foods

(2010) Jeljer Hoekstra et al.   FOOD AND CHEMICAL TOXICOLOGY

A quantitative evaluation of the regulatory assessment of the benefits and risks of rofecoxib relative to naproxen: an application of the incremental net-benefit framework

(2010) Larry D. Lynd et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

A Review of Quantitative Risk–Benefit Methodologies for Assessing Drug Safety and Efficacy—Report of the ISPOR Risk–Benefit Management Working Group

(2010) Jeff J. Guo et al.   VALUE IN HEALTH

An Effective Process for Making Decisions About Major Operating Room Purchases

(2010) Carol Pennington et al.   AORN JOURNAL

The Use of Clinical Utility Assessments in Early Clinical Development

(2009) Anis A. Khan et al.   AAPS Journal

Relative vs. absolute measures of benefit and risk: what’s the difference?

(2009) L. Citrome   ACTA PSYCHIATRICA SCANDINAVICA

—CMR International Institute for Regulatory Science Workshop on Measuring Benefit and Balancing Risk 19–20 June 2008 Washington, DC

(2009) S Walker et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Net efficacy adjusted for risk: further developments

(2009) J Boada et al.   Expert Opinion On Drug Safety

Using the Incremental Net Benefit Framework for Quantitative Benefit–Risk Analysis in Regulatory Decision-Making—A Case Study of Alosetron in Irritable Bowel Syndrome

(2009) Larry D. Lynd et al.   VALUE IN HEALTH

The Use of a Clinical Utility Index to Compare Insomnia Compounds: A Quantitative Basis for Benefit–Risk Assessment

(2008) D Ouellet et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

What is the harm-benefit ratio of Cox-2 inhibitors?

(2008) T P van Staa et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Quantitative risk-benefit analysis of natalizumab

(2008) J. P. Thompson et al.   NEUROLOGY

Net Efficacy Adjusted for Risk (NEAR): A Simple Procedure for Measuring Risk:Benefit Balance

(2008) José N. Boada et al.   PLoS One

Are Adult Patients More Tolerant of Treatment Risks Than Parents of Juvenile Patients?

(2008) F. Reed Johnson et al.   RISK ANALYSIS