Characterization of Intestinal and Hepatic CYP3A-Mediated Metabolism of Midazolam in Children Using a Physiological Population Pharmacokinetic Modelling Approach

Jugular and Portal Vein Volume, Middle Cerebral Vein Velocity, and Intracranial Pressure in Dry Immersion

(2017) Philippe Arbeille et al.   Aerospace Medicine and Human Performance

Inflammation and Organ Failure Severely Affect Midazolam Clearance in Critically Ill Children

(2016) Nienke J. Vet et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Literature Review of Gastrointestinal Physiology in the Elderly, in Pediatric Patients, and in Patients with Gastrointestinal Diseases

(2016) Jane P.F. Bai et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A mechanistic approach to understanding oral drug absorption in pediatrics: an overview of fundamentals

(2014) Nir Debotton et al.   DRUG DISCOVERY TODAY

Assessing circadian rhythms during prolonged midazolam infusion in the pediatric intensive care unit (PICU) children

(2014) Agnieszka Bienert et al.   Pharmacological Reports

A Workflow Example of PBPK Modeling to Support Pediatric Research and Development: Case Study with Lorazepam

(2013) A. R. Maharaj et al.   AAPS Journal

A Semiphysiological Population Pharmacokinetic Model for Dynamic Inhibition of Liver and Gut Wall Cytochrome P450 3A by Voriconazole

(2013) Sebastian Frechen et al.   CLINICAL PHARMACOKINETICS

Ontogeny of oral drug absorption processes in children

(2012) Miriam G Mooij et al.   Expert Opinion on Drug Metabolism & Toxicology

Acute kidney injury reduces the hepatic metabolism of midazolam in critically ill patients

(2011) C. J. Kirwan et al.   INTENSIVE CARE MEDICINE

How important is intestinal cytochrome P450 3A metabolism?

(2009) Antonius E. van Herwaarden et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions

(2008) Simon N. Muchohi et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: The npde add-on package for R

(2008) Emmanuelle Comets et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE