Molecular Indicators of Surface and Bulk Instability of Hot Melt Extruded Amorphous Solid Dispersions
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular Indicators of Surface and Bulk Instability of Hot Melt Extruded Amorphous Solid Dispersions
Authors
Keywords
amorphous molecular dispersions, hot melt extrusion, molecular mobility, physical stability, surface crystallization
Journal
PHARMACEUTICAL RESEARCH
Volume 32, Issue 4, Pages 1210-1228
Publisher
Springer Nature
Online
2014-10-01
DOI
10.1007/s11095-014-1527-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The effect of processing on the surface physical stability of amorphous solid dispersions
- (2014) Ziyi Yang et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Molecular Implications of Drug–Polymer Solubility in Understanding the Destabilization of Solid Dispersions by Milling
- (2014) Ziyi Yang et al. MOLECULAR PHARMACEUTICS
- Stabilisation of amorphous drugs under high humidity using pharmaceutical thin films
- (2013) Yuen Chuen Ng et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Early Stage Phase Separation in Pharmaceutical Solid Dispersion Thin Films under High Humidity: Improved Spatial Understanding Using Probe-Based Thermal and Spectroscopic Nanocharacterization Methods
- (2013) Sheng Qi et al. MOLECULAR PHARMACEUTICS
- Dissolution enhancement of poorly water-soluble APIs processed by hot-melt extrusion using hydrophilic polymers
- (2012) M. Maniruzzaman et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Application of mixtures of polymeric carriers for dissolution enhancement of fenofibrate using hot-melt extrusion
- (2012) Adela Kalivoda et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A New Protocol To Determine the Solubility of Drugs into Polymer Matrixes
- (2012) Aurélien Mahieu et al. MOLECULAR PHARMACEUTICS
- Investigation of preparation methods on surface/bulk structural relaxation and glass fragility of amorphous solid dispersions
- (2011) Peng Ke et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Crystallization Tendency of Active Pharmaceutical Ingredients Following Rapid Solvent Evaporation—Classification and Comparison with Crystallization Tendency from Under cooled Melts
- (2010) Bernard Van Eerdenbrugh et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Drug–Polymer Solubility and Miscibility: Stability Consideration and Practical Challenges in Amorphous Solid Dispersion Development
- (2010) Feng Qian et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Characterisation and Prediction of Phase Separation in Hot-Melt Extruded Solid Dispersions: A Thermal, Microscopic and NMR Relaxometry Study
- (2010) Sheng Qi et al. PHARMACEUTICAL RESEARCH
- Local Mobility in Amorphous Pharmaceuticals—Characterization and Implications on Stability
- (2009) Sisir Bhattacharya et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Effect of Molecular Weight, Temperature, and Additives on the Moisture Sorption Properties of Polyethylene Glycol
- (2009) Jared A. Baird et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Effect of Polymer Hygroscopicity on the Phase Behavior of Amorphous Solid Dispersions in the Presence of Moisture
- (2009) Alfred C. F. Rumondor et al. MOLECULAR PHARMACEUTICS
- Thermodynamics, Molecular Mobility and Crystallization Kinetics of Amorphous Griseofulvin
- (2008) Deliang Zhou et al. MOLECULAR PHARMACEUTICS
- Estimation of Drug–Polymer Miscibility and Solubility in Amorphous Solid Dispersions Using Experimentally Determined Interaction Parameters
- (2008) Patrick J. Marsac et al. PHARMACEUTICAL RESEARCH
- An investigation into the effects of thermal history on the crystallisation behaviour of amorphous paracetamol
- (2007) Sheng Qi et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Characterisation of solid dispersions of paracetamol and EUDRAGIT® E prepared by hot-melt extrusion using thermal, microthermal and spectroscopic analysis
- (2007) Sheng Qi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now