Improved Oral Bioavailability of BCS Class 2 Compounds by Self Nano-Emulsifying Drug Delivery Systems (SNEDDS): The Underlying Mechanisms for Amiodarone and Talinolol
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Title
Improved Oral Bioavailability of BCS Class 2 Compounds by Self Nano-Emulsifying Drug Delivery Systems (SNEDDS): The Underlying Mechanisms for Amiodarone and Talinolol
Authors
Keywords
first pass metabolism, intestinal absorption, intestinal solubilization, intra-enterocyte metabolism, lipophilic drugs, P-gp efflux, self emulsifying drug delivery systems
Journal
PHARMACEUTICAL RESEARCH
Volume 30, Issue 12, Pages 3029-3044
Publisher
Springer Nature
Online
2013-05-18
DOI
10.1007/s11095-013-1063-y
References
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