Classification of the Crystallization Behavior of Amorphous Active Pharmaceutical Ingredients in Aqueous Environments
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Classification of the Crystallization Behavior of Amorphous Active Pharmaceutical Ingredients in Aqueous Environments
Authors
Keywords
active pharmaceutical ingredient, amorphous, crystallization, polarized light microscopy, synchrotron radiation
Journal
PHARMACEUTICAL RESEARCH
Volume 31, Issue 4, Pages 969-982
Publisher
Springer Nature
Online
2013-11-23
DOI
10.1007/s11095-013-1216-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Liquid–Liquid Phase Separation in Highly Supersaturated Aqueous Solutions of Poorly Water-Soluble Drugs: Implications for Solubility Enhancing Formulations
- (2013) Grace A. Ilevbare et al. CRYSTAL GROWTH & DESIGN
- Evaluating the non-isothermal crystallization behavior of organic molecules from the undercooled melt state using rapid heat/cool calorimetry
- (2012) Jared A. Baird et al. CRYSTENGCOMM
- pH-Induced Precipitation Behavior of Weakly Basic Compounds: Determination of Extent and Duration of Supersaturation Using Potentiometric Titration and Correlation to Solid State Properties
- (2012) Yi-Ling Hsieh et al. PHARMACEUTICAL RESEARCH
- An ab initio polymer selection methodology to prevent crystallization in amorphous solid dispersions by application of crystal engineering principles
- (2011) Bernard Van Eerdenbrugh et al. CRYSTENGCOMM
- Solubility Advantage of Amorphous Pharmaceuticals, Part 3: Is Maximum Solubility Advantage Experimentally Attainable and Sustainable?
- (2011) Sharad B. Murdande et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Dissolution and Precipitation Behavior of Amorphous Solid Dispersions
- (2011) David E. Alonzo et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Solution-Mediated Phase Transformation: Significance During Dissolution and Implications for Bioavailability
- (2011) Kristyn Greco et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Excipient-Mediated Supersaturation Stabilization in Human Intestinal Fluids
- (2011) Jan Bevernage et al. MOLECULAR PHARMACEUTICS
- TowardIn SilicoPrediction of Glass-Forming Ability from Molecular Structure Alone: A Screening Tool in Early Drug Development
- (2011) Denny Mahlin et al. MOLECULAR PHARMACEUTICS
- Influence of Particle Size on the Ultraviolet Spectrum of Particulate-Containing Solutions: Implications for In-Situ Concentration Monitoring Using UV/Vis Fiber-Optic Probes
- (2011) Bernard Van Eerdenbrugh et al. PHARMACEUTICAL RESEARCH
- Using polymeric precipitation inhibitors to improve the absorption of poorly water-soluble drugs: A mechanistic basis for utility
- (2010) Dallas B. Warren et al. JOURNAL OF DRUG TARGETING
- A Classification System to Assess the Crystallization Tendency of Organic Molecules from Undercooled Melts
- (2010) Jared A. Baird et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Crystallization Tendency of Active Pharmaceutical Ingredients Following Rapid Solvent Evaporation—Classification and Comparison with Crystallization Tendency from Under cooled Melts
- (2010) Bernard Van Eerdenbrugh et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Small Scale Screening To Determine the Ability of Different Polymers To Inhibit Drug Crystallization upon Rapid Solvent Evaporation
- (2010) Bernard Van Eerdenbrugh et al. MOLECULAR PHARMACEUTICS
- Solubility Advantage of Amorphous Pharmaceuticals: II. Application of Quantitative Thermodynamic Relationships for Prediction of Solubility Enhancement in Structurally Diverse Insoluble Pharmaceuticals
- (2010) Sharad B. Murdande et al. PHARMACEUTICAL RESEARCH
- Understanding the Behavior of Amorphous Pharmaceutical Systems during Dissolution
- (2010) David E. Alonzo et al. PHARMACEUTICAL RESEARCH
- Downscaling Drug Nanosuspension Production: Processing Aspects and Physicochemical Characterization
- (2009) Bernard Van Eerdenbrugh et al. AAPS PHARMSCITECH
- Correlating thermodynamic and kinetic parameters with amorphous stability
- (2009) Kirsten A. Graeser et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Solubility advantage of amorphous pharmaceuticals: I. A thermodynamic analysis
- (2009) Sharad B. Murdande et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Why Do Organic Compounds Crystallise Well or Badly or Ever so Slowly? Why Is Crystallisation Nevertheless Such a Good Purification Technique?†
- (2009) Michael B. Hursthouse et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Top-down production of drug nanocrystals: Nanosuspension stabilization, miniaturization and transformation into solid products
- (2008) Bernard Van Eerdenbrugh et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started