Preclinical Studies of YK-4-272, an Inhibitor of Class II Histone Deacetylases by Disruption of Nucleocytoplasmic Shuttling

Histone Deacetylase Cytoplasmic Trapping by a Novel Fluorescent HDAC Inhibitor

(2011) Y. Kong et al.   MOLECULAR CANCER THERAPEUTICS

Fluorescent Epigenetic Small Molecule Induces Expression of the Tumor Suppressor Ras-Association Domain Family 1A and Inhibits Human Prostate Xenograft

(2010) Kathryn D. Sheikh et al.   JOURNAL OF MEDICINAL CHEMISTRY

SB939, a Novel Potent and Orally Active Histone Deacetylase Inhibitor with High Tumor Exposure and Efficacy in Mouse Models of Colorectal Cancer

(2010) V. Novotny-Diermayr et al.   MOLECULAR CANCER THERAPEUTICS

Involvement of P-glycoprotein and Multidrug Resistance Associated Protein 1 on the Transepithelial Transport of a Mercaptoacetamide-Based Histone-Deacetylase Inhibitor in Caco-2 Cells

(2009) Zacharoula Konsoula et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Pharmacokinetics, disposition and lipid-modulating activity of 5-{2-[4-(3,4-difluorophenoxy)-phenyl]-ethylsulfamoyl}-2-methyl-benzoic acid, a potent and subtype-selective peroxisome proliferator-activated receptor α agonist in preclinical species and human

(2009) K.S. Frederick et al.   XENOBIOTICA

Design, Synthesis, Biological Evaluation and Pharmacokinetics of Bis(hydroxyphenyl) substituted Azoles, Thiophenes, Benzenes, and Aza-Benzenes as Potent and Selective Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1)

(2008) Emmanuel Bey et al.   JOURNAL OF MEDICINAL CHEMISTRY

In VitroMetabolic Stability and Intestinal Transport of P57AS3 (P57) fromHoodia gordoniiand its Interaction with Drug Metabolizing Enzymes

(2008) Vamsi Madgula et al.   PLANTA MEDICA

A modified fast (4 day) 96-well plate Caco-2 permeability assay

(2008) Masashi Uchida et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS