Random Mutagenesis of β-Tubulin Defines a Set of Dispersed Mutations That Confer Paclitaxel Resistance

Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations

(2011) Max A Tischfield et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have  I-Tubulin Mutations and Altered Expression of  II- and  III-Tubulin Isotypes

(2011) A. Kanakkanthara et al.   MOLECULAR CANCER THERAPEUTICS

Discovery and Characterization of the Laulimalide-Microtubule Binding Mode by Mass Shift Perturbation Mapping

(2010) Melissa J. Bennett et al.   CHEMISTRY & BIOLOGY

Tumoral and tissue-specific expression of the major human β-tubulin isotypes

(2010) Luis J. Leandro-García et al.   Cytoskeleton

Mutations in the neuronal β-tubulin subunit TUBB3 result in malformation of cortical development and neuronal migration defects

(2010) Karine Poirier et al.   HUMAN MOLECULAR GENETICS

Inhibition of Cell Migration and Cell Division Correlates with Distinct Effects of Microtubule Inhibiting Drugs

(2010) Hailing Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Mutations That Confer Paclitaxel Resistance

(2010) S. Yin et al.   MOLECULAR CANCER THERAPEUTICS

Paclitaxel-Dependent Cell Lines Reveal a Novel Drug Activity

(2010) A. Ganguly et al.   MOLECULAR CANCER THERAPEUTICS

Microtubule-binding agents: a dynamic field of cancer therapeutics

(2010) Charles Dumontet et al.   NATURE REVIEWS DRUG DISCOVERY

Cancer Cells Acquire Mitotic Drug Resistance Properties Through Beta I-Tubulin Mutations and Alterations in the Expression of Beta-Tubulin Isotypes

(2010) Chun Hei Antonio Cheung et al.   PLoS One

A mutation in β-tubulin and a sustained dependence on androgen receptor signalling in a newly established docetaxel-resistant prostate cancer cell line

(2009) Takahito Hara et al.   CELL BIOLOGY INTERNATIONAL

Molecular Basis for Class V β-Tubulin Effects on Microtubule Assembly and Paclitaxel Resistance

(2009) Rajat Bhattacharya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in the β-tubulin gene TUBB2B result in asymmetrical polymicrogyria

(2009) Xavier Hubert Jaglin et al.   NATURE GENETICS

Molecular Mechanisms of Patupilone Resistance

(2008) S. Mozzetti et al.   CANCER RESEARCH

Microtubule dynamics as a target in oncology

(2008) April L. Risinger et al.   CANCER TREATMENT REVIEWS

A Unique Mode of Microtubule Stabilization Induced by Peloruside A

(2008) J. Torin Huzil et al.   JOURNAL OF MOLECULAR BIOLOGY

Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions

(2008) Tracy Y.E. Liaw et al.   MOLECULAR CANCER THERAPEUTICS