Designing Dendrimers for Drug Delivery and Imaging: Pharmacokinetic Considerations

Design, Synthesis, and Biological Evaluation of a Robust, Biodegradable Dendrimer

(2010) Derek G. van der Poll et al.   BIOCONJUGATE CHEMISTRY

Transport and biodistribution of dendrimers across human fetal membranes: Implications for intravaginal administration of dendrimer-drug conjugates

(2010) Anupa R. Menjoge et al.   BIOMATERIALS

Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications

(2010) Anupa R. Menjoge et al.   DRUG DISCOVERY TODAY

Synthesis, Biodistribution, and Microsingle Photon Emission Computed Tomography (SPECT) Imaging Study of Technetium-99m Labeled PEGylated Dendrimer Poly(amidoamine) (PAMAM)−Folic Acid Conjugates

(2010) Yuanqing Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Anionic Amino Acid Dendrimer−Trastuzumab Conjugates for Specific Internalization in HER2-Positive Cancer Cells

(2010) Takuya Miyano et al.   MOLECULAR PHARMACEUTICS

Regulatory perspective on the importance of ADME assessment of nanoscale material containing drugs

(2009) Banu S. Zolnik et al.   ADVANCED DRUG DELIVERY REVIEWS

γ-Glutamyl PAMAM Dendrimer as Versatile Precursor for Dendrimer-Based Targeting Devices

(2009) Tomoya Uehara et al.   BIOCONJUGATE CHEMISTRY

Unexpected In Vivo Anti-Inflammatory Activity Observed for Simple, Surface Functionalized Poly(amidoamine) Dendrimers

(2009) Abhay S. Chauhan et al.   BIOMACROMOLECULES

Poly(amidoamine) dendrimer–drug conjugates with disulfide linkages for intracellular drug delivery

(2009) Yunus E. Kurtoglu et al.   BIOMATERIALS

Partly PEGylated polyamidoamine dendrimer for tumor-selective targeting of doxorubicin: The effects of PEGylation degree and drug conjugation style

(2009) Saijie Zhu et al.   BIOMATERIALS

NFκB decoy delivery using dendritic poly(l-lysine) for treatment of endotoxin-induced hepatitis in mice

(2009) Yusuke Sugao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Preclinical and clinical studies of anticancer agent-incorporating polymer micelles

(2009) Yasuhiro Matsumura et al.   CANCER SCIENCE

PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats

(2009) Lisa M. Kaminskas et al.   JOURNAL OF CONTROLLED RELEASE

Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy

(2009) Adriana Casas et al.   JOURNAL OF CONTROLLED RELEASE

Partly-PEGylated Poly-L-lysine Dendrimers Have Reduced Plasma Stability and Circulation Times Compared With Fully PEGylated Dendrimers

(2009) L.M. Kaminskas et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Synthesis, Radiolabeling, and Bio-imaging of High-Generation Polyester Dendrimers

(2009) Matthew C. Parrott et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors

(2009) Hemant Sarin et al.   Journal of Translational Medicine

Pharmacokinetics and Tumor Disposition of PEGylated, Methotrexate Conjugated Poly-l-lysine Dendrimers

(2009) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

Synthesis andIn VivoAntitumor Efficacy of PEGylated Poly(l-lysine) Dendrimer−Camptothecin Conjugates

(2009) Megan E. Fox et al.   MOLECULAR PHARMACEUTICS

PEGylated PAMAM Dendrimer-Doxorubicin Conjugates: In Vitro Evaluation and In Vivo Tumor Accumulation

(2009) Saijie Zhu et al.   PHARMACEUTICAL RESEARCH

Biodegradable dendritic positron-emitting nanoprobes for the noninvasive imaging of angiogenesis

(2009) Adah Almutairi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic and diagnostic applications of dendrimers for cancer treatment☆

(2008) J WOLINSKY et al.   ADVANCED DRUG DELIVERY REVIEWS

Clinical toxicities of nanocarrier systems

(2008) Karina R. Vega-Villa et al.   ADVANCED DRUG DELIVERY REVIEWS

PEGylated Dendrimers with Core Functionality for Biological Applications

(2008) Steven J. Guillaudeu et al.   BIOCONJUGATE CHEMISTRY

The effect of surface functionality on cellular trafficking of dendrimers

(2008) Omathanu P. Perumal et al.   BIOMATERIALS

Molecular Targeting and Treatment of Composite EGFR and EGFRvIII-Positive Gliomas Using Boronated Monoclonal Antibodies

(2008) W. Yang et al.   CLINICAL CANCER RESEARCH

The effect of dendrimers on the pharmacodynamic and pharmacokinetic behaviors of non-covalently or covalently attached drugs

(2008) Yiyun Cheng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Generation-dependent encapsulation/electrostatic attachment of phenobarbital molecules by poly(amidoamine) dendrimers: Evidence from 2D-NOESY investigations

(2008) Yiyun Cheng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells

(2008) Hemant Sarin et al.   Journal of Translational Medicine

The Role of the Size and Number of Polyethylene Glycol Chains in the Biodistribution and Tumor Localization of Triazine Dendrimers

(2008) Jongdoo Lim et al.   MOLECULAR PHARMACEUTICS

The Impact of Molecular Weight and PEG Chain Length on the Systemic Pharmacokinetics of PEGylated Polyl-Lysine Dendrimers

(2008) Lisa M. Kaminskas et al.   MOLECULAR PHARMACEUTICS

Endocytosis Inhibitors Prevent Poly(amidoamine) Dendrimer Internalization and Permeability across Caco-2 Cells

(2008) Kelly M. Kitchens et al.   MOLECULAR PHARMACEUTICS

Enhanced Anti-Inflammation of Inhaled Dexamethasone Palmitate Using Mannosylated Liposomes in an Endotoxin-Induced Lung Inflammation Model

(2008) W. Wijagkanalan et al.   MOLECULAR PHARMACOLOGY

Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats

(2007) Wassana Wijagkanalan et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced Oral Bioavailability of Doxorubicin in a Dendrimer Drug Delivery System

(2007) Weilun Ke et al.   JOURNAL OF PHARMACEUTICAL SCIENCES